Publications
Full publication list at Google Scholar.

Dual-Mode Bio-CM²: Multimodal Computational Miniature Mesoscope for Fluorescence and Label-Free Imaging
Dual-Mode Bio-CM2: Multimodal Computational Miniature Mesoscope for Fluorescence and Label-Free Imaging
Qilin Deng, Guorong Hu, Bradley C. Rauscher, Marcelo Villafuerte, Bethany Weinberg, Zhixiong Chen, Hui Feng, Anna Devor, Martin Thunemann, and Lei Tian
bioRxiv, 2026.09.08.750281 (2026). Preprint.

Point Spread Function Engineering Using Implicit Neural Representations
Point Spread Function Engineering Using Implicit Neural Representations
Suet Ying Chan, Mitchell Gilmore, Qilin Deng, Guorong Hu, Joseph Greene, Ruipeng Guo, and Lei Tian
arXiv:2608.20277 (2026). Preprint.

Bio-CM²: Distributed computational optics for cortex-wide cellular imaging
Bio-CM2: Distributed computational optics for cortex-wide cellular imaging
Guorong Hu, Qilin Deng, Tianrui Qi, Zhixiong Chen, Bradley C. Rauscher, Nathan Chai, Daria Bogatova, Bethany Weinberg, Jesse Smith, Ian G. Davison, Martin Thunemann, Anna Devor, and Lei Tian
bioRxiv, 2026.07.27.740823 (2026). Preprint.

DeepFilters: Scattering-Aware Pupil Engineering with Learned Digital Filter Reconstruction for Extended Depth of Field Microscopy
DeepFilters: Scattering-Aware Pupil Engineering with Learned Digital Filter Reconstruction for Extended Depth of Field Microscopy
Joseph L. Greene, Suet Ying Chan, Qilin Deng, Jeffrey Alido, Alexandra Lion, Guorong Hu, Ruipeng Guo, Tongyu Li, Kivilcim Kiliç, Ian Davison, and Lei Tian
arXiv:2605.13619 (2026). Preprint.
Versatile high-speed volumetric imaging from microscopic to macroscopic scale by self-adaptive oblique plane microscopy
Versatile high-speed volumetric imaging from microscopic to macroscopic scale by self-adaptive oblique plane microscopy
Dominique Meyer, Grant Kroeschell, Xiankun Lu, Linh Hoang, Haochen Wang, Shuying Li, Yu Kang T Xu, Lei Tian, Jeff S Mumm, Dwight E Bergles, and Ji Yi
bioRxiv, 2025.12.16.694458 (2026). Preprint.

Physics-informed neural network for mapping vascular and tissue dynamics using laser speckle contrast imaging
Physics-informed neural network for mapping vascular and tissue dynamics using laser speckle contrast imaging
Shuying Li, Rockwell Tang, Bingxue Liu, Victoria Krepulec, Will Donovan, David Boas, Xiaojun Cheng, and Lei Tian
Neurophotonics, Vol. 13, Issue 3, 035012, 2026.

Dual-wavelength Fourier Ptychographic Topography
Dual-wavelength Fourier Ptychographic Topography
Yi Shen, Tongyu Li, Hao Wang, Jinyong Kim, Hojun Lee, Wookrae Kim, Jonghyeok Park, Junho Shin, Seungbeom Park and Lei TianIEEE Transactions on Computational Imaging 2026.

Coordinate-conditioned Deconvolution for Scalable Spatially Varying High-Throughput Imaging
Coordinate-conditioned Deconvolution for Scalable Spatially Varying High-Throughput Imaging
Qianwan Yang; Zhixiong Chen; Jiaqi Zhang; Ruipeng Guo; Guorong Hu; Lei Tian
IEEE Transactions on Computational Imaging 2026.

An end-to-end hybrid deep-learning approach for single-shot wavefront sensing and correction
An end-to-end hybrid deep-learning approach for single-shot wavefront sensing and correction
Sina Moayed Baharlou, Muhammad Waleed Khalid, Guli Gulinihali, Jeongho Ha, Liyi Hsu, Samantha C. Lewis, Lei Tian, Yeshaiahu Fainman, Alexander V. Sergienko, and Abdoulaye Ndao
Nature Communications 17, 6340 (2026).

Dual-channel event microscopy for ultrafast biological imaging
Dual-channel event microscopy for ultrafast biological imaging
R. Guo, X. Pan, Q. Deng, A. Ahmed, Q. Yang, J. Greene, T. Li, S.Y. Chan, Z. Chen, G. Hu, H. Feng, & L. Tian
Proc. Natl. Acad. Sci. (PNAS) 123 (17) e2531386123

Mid-infrared photothermal relaxation intensity diffraction tomography for video-rate volumetric chemical imaging
Mid-infrared photothermal relaxation intensity diffraction tomography for video-rate volumetric chemical imaging
Danchen Jia, Dashan Dong, Tongyu Li, Haonan Zong, Jiabei Zhu, Xinyan Teng, Lei Tian, and Ji-Xin Cheng
Optics Express 34, 16440–16453 (2026).
Transfer-function approach to substrate-enhanced diffraction tomography
Transfer-function approach to substrate-enhanced diffraction tomography
Tongyu Li, Yi Shen, Dashan Dong, Danchen Jia, Jianpeng Ao, Ji-Xin Cheng, and Lei Tian
Optica, 2026.
⭑ Github Project

The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions
The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions
B. C. Rauscher, N. Fomin-Thunemann, S. Kura, P. R. Doran, P. D. Perez, K. Kılıç, E. A. Martin, D. Balog, N. X. Chai, F. A. Froio, P. F. Bloniasz, K. E. Herrema, R. P. Tang, S. G. Knudstrup, A. Garcia, J. X. Jiang, J. P. Gavornik, M. London, D. Kleinfeld, M. E. Hasselmo, L. D. Lewis, S. Sakadzic, L. Tian, G. Mishne, E. P. Stephen, M. Thunemann, D. A. Boas, and A. Devor
Nature Neuroscience 29, 1203–1211 (2026).

Reflection-mode Multi-slice Fourier Ptychographic Tomography
Reflection-mode Multi-slice Fourier Ptychographic Tomography
J Zhu, T Li, H Wang, Y Shen, G Hu, L Tian
IEEE Transactions on Computational Imaging, 2026
⭑ Github Project

Roadmap on deep learning for microscopy
Roadmap on deep learning for microscopy
Giovanni Volpe, Carolina Wählby, Lei Tian, et al.
JPhys. Photonics 8(1), 012501 (2026). Review / Roadmap.

Whitened Score Diffusion: A Structured Prior for Imaging Inverse Problems
Whitened Score Diffusion: A Structured Prior for Imaging Inverse Problems
J Alido, T Li, Y Sun, L Tian
NeurIPS 2025.
⭑ Github Project

In vivo fundus imaging and computational refocusing with a diffuser-based fundus camera
In vivo fundus imaging and computational refocusing with a diffuser-based fundus camera
Corey Simmerer, Marisa Morakis, Lei Tian, Lia Gomez-Perez, T. Y. Alvin Liu, and Nicholas J. Durr
Biophotonics Discovery 2(4), 042306 (2025).

Age-informed, attention-based weakly supervised learning for neuropathological image assessment
Age-informed, attention-based weakly supervised learning for neuropathological image assessment
Shuying Li, Maxwell Malamut, Ann McKee, Jonathan D Cherry, Lei Tian
Brain Informatics 12 (1), 27

Self-supervised elimination of non-independent noise in hyperspectral imaging
Self-supervised elimination of non-independent noise in hyperspectral imaging
G Ding, C Liu, J Yin, X Teng, Y Tan, H He, H Lin, L Tian, JX Cheng
Newton 1 (6)

Ultrafast tomograms in a flash
Ultrafast tomograms in a flash
Lei Tian
Science Advances 11(33), eaea2494 (2025). Focus / Commentary.