Epidemiology: Burden, Risks, and Outcomes of HIV Treatment and Prevention

Since 2008, our group has used large clinical HIV treatment databases to understand the impact of South Africa’s National HIV Treatment Program with a focus on retention in HIV care (including both on treatment and linkage to care). We have done extensive work in analyzing the impact of changes to South Africa’s treatment program. We use the tools of epidemiology to understand the burden of HIV and related conditions, assess transmission and treatment failure risks, estimate outcomes of treatment and prevention interventions, and provide the effectiveness component of cost-effectiveness analysis. We have also innovated in the areas of study design, analytic methods and in record linkage.

Follow the links below for more information about the projects, publications, and investigators involved.

Other publications and documents

Govender K, Long L, Miot J. Progress towards unique patient identification and case-based surveillance within the Southern African development community. Health Informatics Journal. 2023;29(1). doi:10.1177/14604582221139058

Zaniewski E, et al. Trends in CD4 and viral load testing 2005 to 2018: multi-cohort study of people living with HIV in Southern Africa. J Int AIDS Soc 2020;23:e25546.

Bor J, Fischer C, Modi M, Richman B, Kinker C, King R, Calabrese SK, Mokhele I, Sineke T,  Zuma T, Rosen S, Bärnighausen T, Mayer KH, Onoya D. Changing knowledge and attitudes towards HIV treatment-as-prevention and “undetectable = untransmittable”: a systematic review. AIDS & Behaviour 2021.

Onoya D, Sineke T, King R, Mokhele I, Sharma S, Dukashe M, et al. (2023) Designing effective U = U communication strategies considering the needs of PLHIV, their partners, and healthcare worker constraints in South African clinics. PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920.