Interactive Datasets
1) Werder et al. The American Journal of Human Genetics. 2023 doi:10.1016/j.ajhg.2023.08.017.
See the effect of ADGRG6 knockdown on gene expression in iPSC-derived AT2s! SPRING or Shiny App from Figure 3 (scRNAseq of BU3NGST-CRISPRi iAT2s in 3D +/- ADGRG6 knockdown)
2) Kaserman et al. Cell Reports. 2022 41, 111775.
a) Click here to interact with bulk RNA sequencing from syngeneic, CRISPR-edited PiZZ6 ZZ vs MZ vs MM iHeps from Figure 2
b) Click here to interact with metabolomics from syngeneic, CRISPR-edited PiZZ6 ZZ vs MZ vs MM iHeps from Figure 3
c) Click here to interact with scRNAseq data (shiny app of scRNAseq of PiZZ6-ZZ vs PiZZ1-ZZ vs MZ vs MM iHeps) from Figure 5
d) Click here to interact with scRNAseq data (SPRING of scRNAseq of PiZZ6-ZZ vs PiZZ1-ZZ vs MZ vs MM iHeps) from Figure 5
3) Werder et al. Sci Adv. 2022 Jul 15;15;8(28):eabo6566.
Click here to see the effect of DSP knockdown on gene expression in iPSC-derived AT2s! SPRING from Figure 4 (scRNAseq of BU3NGST-CRISPRi iAT2s in 3D +/- DSP knockdown)
4) Abo et al. JCI Insight. 2022 Mar 22;7(6):e155589.
Click here to see the effect of ALI culture or cigarette smoke exposure on your favorite gene in iPSC-derived AT2s! SPRING from Figure 4 (scRNA-seq of SPC2 iAT2s in 3D, 2D, ALI, and smoke-exposed ALI cultures).