Selected Publications

  1. Abo et al. Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium. JCI Insight. 2022;7(6):e155589. PMID: 35315362.

    Click for pdf: Abo et al. JCI Insight 2022.

  2. Werder RB et al. Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient iPSC-hepatocytes. Molecular Therapy. Nov 3 2021. PMID: 34217893.

    Click for pdf: Werder et al. Mol Ther 2021

  3. Heckman RM et al. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Molecular Cell. Dec 17 2020. PMID: 33259812.

    Click for pdf: Heckman et al. Mol Cell 2021.

  4. Huang J et al. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. Dec 3 2020. PMID: 32979316.

    Click for pdf: Huang et al. Cell Stem Cell 2020

  5. Kaserman JE et al. A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells. Stem Cell Reports. Jul 14 2020. PMID: 32619491.

    Click for pdf: Kaserman et al. Stem Cell Reports 2020

  6. Kaserman JE et al. Protocol for Directed Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) to a Hepatic Lineage. Methods Mol. Biol. 2017. PMID: 28752455.
  7. Payne JG et. al. Multilineage Transduction of Resident Lung Cells in vivo by AAV2/8 for α1-Antitrypsin Gene Therapy Molecular Therapy, Methods & Clinical Development. Jun 29 2016. PMID: 27408904

    Click for pdf: Payne et al. Mol Ther Methods Clin Dev 2016

  8. Wilson AA et. al. Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells Stem Cell Reports. Apr 2nd 2015. PMCID: PMC4437473

    Click for pdf: Wilson et al. Stem Cell Reports 2015

  9. Wilson AA et. al. Lentiviral Delivery of RNAi for In Vivo Lineage-Specific Modulation of Gene Expression in Mouse Lung Macrophages Molecular Therapy. Feb 2013. PMCID: PMC3616534

    Click for pdf: Wilson et al. Molecular Therapy 2013

  10. Wilson AA et. al. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. Journal of Clinical Investigation. Jan 2010.PMID: 20038801

    Click for pdf: Wilson et al. J Clin Invest 2010

  11. Wilson AA et. al. Sustained Expression of α1-Antitrypsin after Transplantation of Manipulated Hematopoietic Stem Cells American Journal of Respiratory Cell Molecular Biology. Aug 2008. PMID: 18323534

    Click for pdf: Am. J. Respir. Cell Mol. Biol. 2008 Wilson