Many years ago we began working on an unknown protein named KIAA1787, now known as NEURL4. Here we report our studies on its role as a mitochondrial ADP-ribosyltransferase and a new member of the ARTD family: https://www.biorxiv.org/content/10.1101/2020.12.28.424513v1. We are very excited about this finding and look forward to hearing comments and feedback.
Want to learn how we optimized the chromatin immunoprecipitation protocol for efficient ChIP from mouse brown adipose tissue? We hope this visual protocol can be helpful. Please reach out if you have questions! https://www.jove.com/video/58682/chromatin-immunoprecipitation-of-murine-brown-adipose-tissue
We are very proud of our latest story now finally out today in Molecular Cell!! Read here how GPS2 regulates Mitochondrial Retrograde Signaling in Mammalian Cells: http://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30096-0 A big thank to everyone who has worked hard across the country to make this happen!
Watch Valentina and Carly discussing our most recent findings about the role of GPS2 in the insulin signaling pathway at http://www.molecularmetabolism.com/60s_metabolist.php
Congratulations to Claudia and all her collaborators! Their work characterizing GPS2 knock-out in B cells is now in press at JBC: http://www.jbc.org/cgi/content/long/M116.755132v1
Congratulations to Carly and all her co-authors for the exciting discovery of a novel player in the insulin signaling pathway now in press at Molecular Metabolism (http://dx.doi.org/10.1016/j.molmet.2016.10.007). Dissecting the phenotype of GPS2 adipo-specific KO mice has been a long and painful process but the hard work has paid off! Not only a few more tiles have been added to […]
Congratulations to Jiawen, Dafne and Holly for their paper on the regulation of GPS2 stability now accepted for publication in JBC: http://www.jbc.org/content/early/2015/06/12/jbc.M115.637660.abstract
Dafne’s paper on GPS2 and PPARgamma is now online: http://www.cell.com/cell-reports/abstract/S2211-1247(14)00435-5 Congratulations to everyone for a great work!