Cloud of words most represented in our abstracts  as of May 2020.

Lab Publications

Chan S., Smith E., Gao Y., Kwan J., Blum B.C., Tilston-Lunel A.M., Turcinovic I., Varelas X., Cardamone M.C., Monti S., E,mili A., Perissi V. Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling. Frontiers Cell and Developmental Biology, 07 January 2021 |https://doi.org/10.3389/fcell.2020.608044

English J, Son JM, Cardamone MD, Lee C, Perissi V. Decoding the rosetta stone of mitonuclear communication. Pharmacological Research.  Nov;161:105161, 2020

Cardamone M.D., Orofino J., Labadorf A., Perissi V.. Chromatin Immunoprecipitation of Murine Brown Adipose Tissue. J Vis Exp. Nov 21;(141), 2018

Cardamone M.D., Tanasa B*., Cederquist C.T.*, Huang J., Mahdaviani K., Li W., Rosenfeld M.G., Liesa M., Perissi V.  Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Molecular Cell, 69(5):757-772, 2018

Lentucci C., Belkina A.*, Cederquist C.T.*, Chan M., Johnson H.E., Prasad S., Lopacinski A., Nikolajczyk B.S., Monti S., Snyder-Cappione J., Tanasa B., Cardamone M.D., Perissi V.  Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. Journal of Biological Chemistry, 292(7):2754-2772, 2017

Cederquist C.T., Lentucci C., Martinez-Calejman C., Hayashi V., Orofino J., Guertin D., Fried S.K., Lee M.J., Cardamone M.D., Perissi V. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Molecular Metabolism6(1):125-137, 2016.

Huang J*, Cardamone M.D.*, Johnson H.E., Neault M., Chan M., Floyd E.Z., Mallette F.A., Perissi V. Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation. Journal of Biological Chemistry290(31):19044-54, 2015

Cardamone M.D., Tanasa B., Chan M., Cederquist C.T., Andricovich J., Rosenfeld M.G., Perissi V. GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ. Cell Reports 8(1):163-76, 2014

Cardamone M.D., Krones A., Tanasa B., Taylor H., Ricci L., Ohgi K.A., Glass C.K., Rosenfeld M.G. & Perissi V.  A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.  Molecular Cell, 46 (1): 91-104, 2012

 

 

 

Collaborations

Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Molecular Cell  Jan 7;81(1):212, 2021

Jones J.E.C., Rabhi N., Orofino J., Gamini R., Perissi V., Vernochet C., Farmer S.R. The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet. Scientific Reports Feb 11;10(1):2380, 2020

Lima T.I., Guimarães D.S.P.S.F., Oliveira A.G., Araujo H., Sponton C.H.G., Souza-Pinto N.C., Saito Â., Figueira A.C.M., Palameta S., Bajgelman M.C., Calixto A., Pinto S., Mori M.A., Orofino J., Perissi V., Mottis A., Auwerx J., Silveira L.R. Opposing action of NCoR1 and PGC-1α in mitochondrial redox homeostasis. Free Radic Biol Med. Nov 1;143:203-208, 2019

Vincent A.E., Rosa H.S., Pabis K., Lawless C., Chen C., Grünewald A., Rygiel K.A., Rocha M.C., Reeve A.K., Falkous G., Perissi V., White K., Davey T., Petrof B.J., Sayer A.A., Cooper C., Deehan D., Taylor R.W., Turnbull D.M., Picard M. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Annals of Neurology Aug;84(2):289-301, 2018

Mahdaviani K., Benador I.Y., Su S., Gharakhanian R.A., Stiles L., Trudeau K.M., Cardamone M., Enríquez-Zarralanga V., Ritou E,. Aprahamian T., Oliveira M.F., Corkey B.E., Perissi V., Liesa M., Shirihai O.S. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.  EMBO Reports, 18(7):1123-1138, 2017.

 

Other Relevant Publications

Scafoglio C., Smolka M., Zhou H., Perissi V., Rosenfeld MG. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. PLOS One 8 (5): e59986, 2013

Perissi V., Jepsen K., Glass C.K. and Rosenfeld M.G. Deconstructing repression: evolving models of co-repressor action. Nature Reviews Genetics, 11(2): 109-23, 2010

Perissi V., Scafoglio C., Zhang J., Ohgi K.A., Rose D.W., Glass C.K. & Rosenfeld M.G. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints.  Molecular Cell, 29 (6), 755-66, 2008

Perissi V. and Rosenfeld M.G. Controlling nuclear receptors: the circular logic of cofactor cycles.  Nature Reviews Molecular Cell Biology, 6 (7), 542-554, 2005

Perissi V., Aggarwal A., Glass C.K., Rose D.W. & Rosenfeld M.G. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.  Cell, 116(4): 511-26, 2004

Li X., Perissi V., Liu F., Rose D.W., Rosenfeld M.G. Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science, 16(5584):1180-3, 2002

Wen Y.D., Perissi V., Staszewski L.M., Yang W.M., Krones A., Glass C.K., Rosenfeld M.G., Seto E. The histone deacetylase-3 complex contains nuclear receptor corepressors. PNAS, 97(13), 7202-7207, 2000

Perissi V., Menini N., Cottone E., Capello D., Sacco M., Montaldo F., De Bortoli M. AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen. Oncogene, 19 (2), 280-288, 2000

Perissi V., Staszewski L.M., McInerney E.M., Kurokawa R., Krones A., Rose D.W., Lambert M.H., Milburn M.V., Glass C.K. & Rosenfeld M.G.  Molecular determinants of nuclear receptor-corepressor interaction.  Genes&Development, 13 (24), 3198-3208, 1999

Perissi V., Dasen J.S., Kurokawa R., Wang Z., Korzus E., Rose D.W., Glass C.K., Rosenfeld M.G. Factor-specific modulation of CREB-binding protein acetyltransferase activity. PNAS, 96(7), 3652-3657, 1999