Research
Adaptive ultrasound beamformingImproved ultrasound images are obtained by suppression of incoherent clutter and noise. Read more… |
High contrast voltage imagingGenetically encoded voltage indicators (GEVIs) are imaged at kilohertz rates by targeted-illumination and confocal microscopy. Read more… |
Deblurring by pixel reassignmentGeneral algorithm for image sharpening is based on pixel reassignment. Read more… |
Imaging at trillion frames per secondSingle-shot non-synchronous array photography (SNAP) is performed with time-to-angle multiplexing. Read more… |
Ultrafast laser scanningA passive scan multiplier unit enables a galvanometer to perform high throughput ultrafast laser scanning beyond the inertia limit. Read more… |
Laser speckle contrast imagingMultifocus laser speckle contrast imaging (LSCI) reveals mixed blood-flow dynamics in the brain. Read more… |
Ultrasound phase-contrast imagingDifferential phase contrast using the memory effect enables a standard US imaging device to reveal subsurface speed-of-sound variations in real time. Read more… |
Widefield multifocus imagingHigh-contrast multifocus microscopy is performed with a single camera and versatile z-splitter prism. Read more… |
Retroillumination corneal imagingWidefield corneal imaging is performed by oblique retroillumination microscopy. Read more… |
Reverberation multiphoton microscopyQuasi-simultaneous multiplane imaging is performed using temporal multiplexing with a reverberation loop. Read more… |
Multi-Z confocal microscopySimultaneous multiplane imaging is performed over large fields of view at rates up to a kilohertz. Read more… |
Compressive flow cytometryHigh-throughput flow cytometry is performed with matched-filter compressive imaging. Read more… |
Transcranial retinal imagingTranscranial retinal imaging is a method for transilluminating the ocular fundus (i.e. the back of the eye). Read more…
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Extended-depth-of-field microscopyComputational and physical variations of extended-depth-of-field (EDOF) imaging lead to increased contrast. Read more…
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Oblique back-illumination microscopyOBM provides DIC-like phase contrast in arbitrarily thick tissue. The technique is simple, fast, and can be implemented in camera- or scanning-based configurations. Read more… |
Active illumination microscopyAIM significantly increases the dynamic range and enhances the weak-signal sensitivity of a scanning fluorescence microscope, without loss of information. Read more… |
Imaging through complex mediaVariants of adaptive optics are used to improve imaging through an aberrating screen or to control spectral decorrelation through a scattering medium. Read more… |
Imaging through a single optical fiberSelf-luminous objects are imaged through a single optical fiber using spread-spectral encoding. The method contains no moving parts and is insensitive to fiber bending. Read more… |
Partitioned aperture wavefront imagingSingle-shot, quantitative phase imaging using a specially constructed lens. Our technique is achromatic, polarization independent, and light-efficient. Read more… |
HiLo microscopyHiLo microscopy enables a standard widefield fluorescence or reflectance microscope to provide optical sectioning by using two images acquired with uniform and non-uniform (or “structured”) illumination. Read more… |
Differential aberration imagingDAI enables multiphoton contrast enhancement by near-instantaneously acquiring non-aberrated and aberrated images. Read more… |
Dynamic speckle illumination microscopyDSI microscopy enables a standard widefield fluorescence microscope to provide optical sectioning by using randomly changing speckle illumination. Read more… |
Autoconfocal microscopyAutoconfocal microscopy (ACM) enables a two-photon excited fluorescence microscope to produce simultaneous phase contrast by using a virtual pinhole in the transmission direction. Read more… |
Graded field microscopyGraded field microscopy reveals phase gradients in a sample by combining oblique illumination with oblique detection. The resulting image resembles DIC. Read more… |
Nonlinear microscopyNonlinear optical microscopy provides contrast based on a nonlinear interaction of light and matter. Examples include two-photon excited fluorescence (TPEF) and second harmonic generation (SHG) microscopy. Read more… |