Sex-Specific Differences in Plasma Lipid Profiles are Associated with GWI

Prior research indicates that chemical exposures from the Gulf War impact lipid homeostasis, as well as contribute to inflammatory and metabolic dysfunction. Having seen lipid sex-specific differences in animal models, researchers sought to examine human plasma lipids. Distinct differences were found in the lipid profiles of males versus females with GWI. 

Brain-Immune Interactions as Basis for GWI

30 years later, the mechanisms underlying GWI remain unclear. The Gulf War Illness Consortium (GWIC) is a collaborative, interdisciplinary research program working to identify the basis of GWI. The Consortium ran this project out of three-sites, Boston, Houston, and Miami, looking to better understand the alterations to brain and immune function in those with GWI. […]

Neuroimaging Markers for Studying Gulf War Illness

In a sample population of veterans from the Gulf War Illness Consortium (GWIC), multiple different neuroimaging techniques were applied to look for diagnostic biomarkers. Statistical analyses compared T1-weighted magnetic resonance imaging (T1W-MRI), diffusion tensor imaging (DTI), and novel neurite density imaging (NDI). Results supported previous findings that NDI is most effective in distinguishing characteristics of […]

Plasma Autoantibodies as a Diagnostic Tool for GWI

This study, featured on the cover of this issue of the Brain Sciences journal, puts forth groundbreaking implications for diagnosing Gulf War Illness (GWI). Adding to the frustration of GWI, is the fact that to date, there isn’t an objective tool for diagnosis. Findings of this research revealed significant elevation in Central Nervous System (CNS) […]