Hagedorn Lab

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  • Zebrafish embryo with orange macrophages and purple blood vessels

  • Neurons (red), nuclei (blue) and vessels (green) in zebrafish

  • Our laboratory space on the BUMC campus

  • Green erythrocytes (red blood cells) circulating through blood vessels (red color) in zebrafish

  • The Evans Biomedical Research Center (our home) on the BUMC campus

  • Endothelial cells growing on a glass bead

  • Boston and Cambridge at night

  • Multicolored blood vessels in zebrafish

  • Longfellow Bridge over the Charles River

  • Blood stem cells in their niche

  • Hagedorn Lab Members

Welcome to the Hagedorn Lab!

Our research objective is to understand the basic cellular and molecular mechanisms that regulate the movement of cells into and out of distinct tissues and organs. Our long-term goal is to be able to therapeutically control cell migration within specific tissues – to inhibit it in some contexts (e.g., cancer metastasis) and promote it in others (e.g., cellular therapies). We use the zebrafish (Danio rerio) as a uniquely powerful model organism and work closely with clinical and biomedical researchers across the BU/BUMC campuses to translate our basic findings in the fish towards clinical therapies for treating human diseases.

We are a diverse team of researchers from different countries and from different parts of the U.S. Our lab culture is defined by the unique perspectives and experiences that we each bring with us. We aim to create a safe space for all members to learn, grow and succeed in their life goals, and we are committed to promoting diversity, equity, and inclusion in the sciences. Acknowledging that we all have a role to play, the members of the Hagedorn Lab are dedicated to welcoming and celebrating individuals of all races, ethnicities, social backgrounds, religion, gender, sex, age, disability, sexual orientation, veteran status and national origin.

Click here to learn more about our anti-racism efforts: https://www.bumc.bu.edu/hematology/hematology-oncology-diversity-and-inclusion/

Members of our group gain research experience and receive extensive training that prepares them for graduate/medical school and careers in industry, medicine and academic research. Send an email to hagedorn@bu.edu if you are interested in joining our growing team!

We are grateful to the National Institutes of Health and to the Section of Hematology and Medical Oncology at BUMC for funding our research.