Utilizing a mouse model of GWI, researchers examined the potential of β-adrenergic (beta-adrenergic) receptor inhibitor and anti-inflammatory drug, propranolol, as a treatment for GWI. Findings indicate that anti-neuroinflammatory drugs, such as proranolol, show promising potential in treating the underlying neuroimmune issues associated with GWI.
Mouse or rat models of Gulf War Illness are commonly used prior to human experimentation. Abstracts of some recent studies utilizing a mouse model of GWI are linked below. Prolonged Antibiotic Use Worsens Neuroinflammation and Increases the Risk of Neurodegeneration via Elevated Expression of Systemic IL-6 in Gulf War Illness Symptom Persistence Murine Model Nexinhib […]
Utilizing a mouse model of GWI, this study examines the impact of obesity on GWI-related gastrointestinal (GI) inflammation through microbial analysis. The research also addresses the gut-brain connection, and how GI and neuronal inflammation provide increased risk of cognitive deficiencies.