Publications

2017

48. Ceccaldi P, Schuchmann K, Müller V, Elliott SJ, “The hydrogen dependent CO2 reductase: the first completely CO tolerant FeFe-hydrogenase,” Energy and Environmental Science , 2017, 10, 503-508. [DOI]

2016

47. Maiocco SJ, Arcinas A, Landgraf B, Lee K-H, Booker SJ, Elliott SJ, “Transformations of the FeS clusters of the methylthiotransferases MiaB and RimO, detected by direct electrochemistry,” Biochemistry, 2016, 55(39), 5531-5536. [DOI]

46. Dowling D, Miles Z, Köhrer C, Maiocco SJ, Elliott SJ, Bandarian V, Drennan, CL. “Molecular basis of Cobalamin-dependent RNA modification”, Nucleic Acids Research, 2016, 44(20):9965-9976. [DOI]

45. Blaszczyk AJ, Silakov A, Zhang B, Maiocco SJ, Lanz ND, Kelly WL, Elliott SJ, Krebs C, Booker SJ. “Spectroscopic and Electrochemical Characterization of the Iron-Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase”, J. Am. Chem. Soc. 2016, 138(10), 3416-3426. [DOI]

44. Li B and Elliott SJ. “The catalytic bias of 2-oxoacid:ferredoxin oxidoreductase in CO2 evolution and reduction through a ferredoxin-mediated electrochemical assay,” Electrochimica Acta, 2016, 199, 349-356. [DOI]

2015

43.  Frato KE, Walsh KW, Elliott SJ. “Functionally distinct bacterial cytochrome c peroxidases proceed through a common (electro)catalytic intermediate,” Biochemistry, 2015, 55(1),125-132. [DOI]

42. Wei Y, Li B, Prakash D, Ferry J, Elliott SJ, Stubbe J. “A ferredoxin disulfide reductase delivers electrons to the Methanosarcina barkeri class III ribonucleotide reductase,” Biochemistry, 2015, 54(47), 7019-7028. [DOI]

41. Stein N, Love D, Judd ET, Elliott SJ, Bennett B, Pacheco AA. “Correlations between the Electronic Properties of Shewanella oneidensis Cytochrome c Nitrite Reductase and Its Structure: Effects of Heme Oxidation State and Active Site Ligation,” Biochemistry, 2015, 54(24): 3749-58. [DOI]

40. Maiocco SJ, Grove TL, Booker SJ, Elliott SJ. “Electrochemical Resolution of the [4Fe-4S] Centers of the AdoMet Radical Enzyme BtrN: Evidence of Proton Coupling and an Unusual, Low- Potential Auxiliary Cluster,” J. Am. Chem. Soc. , 2015, 127(37): 8664-8667. [DOI]

39. Bewley KD, Dey M, Mitra S, Chobot SE, Drennan CL and Elliott SJ. “Rheostat re-wired: tuning reduction potentials of disulfide bonds independently of Cys pKas”, PLOS-One, 2015. [DOI]

38. Levin BD, Walsh KA, Sullivan KK, Bren KL, Elliott SJ, “Methionine Ligand Lability of Homologous Monoheme Cytochromes c”, Inorganic Chemistry, 2015, 54 (1):38-46. [DOI]

2014

37. Hu W, Song H, Sae Her A, Bak DW, Naowarojna N, Elliott SJ, Qin L, Chen X, Liu P,
“Bioinformatic and Biochemical Characterizations of C-S Bond Formation and Cleavage Enzymes in the Fungus Neurospora crassa Ergothioneine Biosynthetic  Pathway,” Organic Letter, 2014, 16(20): 5382-5385. [DOI]

36. Judd ET,  Stein N, Pacheco AA, Elliott SJ, “Hydrogen Bonding Networks Tune Proton-Coupled
Redox Steps During the Enzymatic Six-electron Conversion of Nitrite to Ammonia,” Biochemistry, 2014, 53 (35): 5638-5646. [DOI]

35. Funk MA, Judd ET, Marsh ENG, Elliott SJ, Drennan CL, “Structures of benzylsuccinate synthase
elucidate roles of accessory subunits in glycyl radical enzyme activation and activity,” Proc. Natl. Acad. Sci. , 2014, 111(28): 10161-10166. [DOI]

34. Bak DW and Elliott SJ, “Alternative FeS cluster ligands: tuning redox potentials and chemistry,” Current Opinions in Chemical Biology, 2014, 19: 50-58. [DOI]

2013

33. Bak DW and Elliott SJ, “Conserved hydrogen bond networks tune FeS cluster binding and structural stability,” Biochemistry, 2013, 52(27): 4687-4696. [PDF]

32. Duncan GGM, Marritt SJ, Firer-Sherwood MA, Shi L, Richardson DJ, Evans SD, Elliott SJ,
Butt JN, Jeuken LJC. “Protein-Protein Interaction Regulates the Direction of Catalysis and Electron Transfer in a Redox Enzyme Complex,” J. Am. Chem. Soc., 2013,135 (28):10550-10556. [DOI]

31. Bewley KD, Ellis KE, Firer-Sherwood MA, Elliott SJ. “Multi-heme proteins: Nature’s electronic multi-purpose tool,” Biochimica et Biophysica Acta – Bioenergetics, 2013, 1827 (8-9): 938-94. [DOI]

2012

30. Judd ET, Youngblut M, Pacecho AA, Elliott SJ. “Direct electrochemistry of Shewanella oneidensis cytochrome c nitrite reductase: evidence for interactions across the dimeric interface,” Biochemistry, 2012, 51 (51):10175-85. [PDF]

29. Ellis KE, Frato KE, Elliott SJ. “Impact of Quarternary Structure upon Bacterial Cytochrome c Peroxidases: does homodimerization matter?” Biochemistry, 2012, 51(50): 10008-10016. [PDF]

28. Hamill MJ, Jost M, Wong C, Bene NC*, Drennan CL, Elliott SJ. “Electrochemical characterization of Escherichia coli adaptive response protein AidB”, International Journal of Molecular Sciences, 2012, 13(12), 16899-16915. [DOI]

27. Bewley KD, Firer-Sherwood MA, Mock JY*, Ando N, Drennan CL, Elliott SJ. “Mind the gap: diversity and reactivity of multiheme cytochromes of the MtrA/DmsE family,” Transactions of the Biochemical Society, 2012, 40(6), 1268-1273. [DOI]

26. Goldman PJ, Ryan KS, Hamill MJ, Howard-Jones AR, Walsh CT, Elliott SJ, Drennan CL. “Unusual Role for a Mobile Flavin in a StaC-like Indolocarbazole Biosynthetic Enzyme,” Chemistry & Biology, 2012, 19(7), 855-865. [DOI]

25. Seidel J, Hoffmann M, Ellis KE, Seidel A, Spatzal T, Gerhardt S, Elliott SJ, Einsle O. “MacA is a Second Cytochrome c Peroxidase of Geobacter sulfurreducens”, Biochemistry, 2012, 50(21), 4513-20. [PDF]

24. Youngblut M, Judd EJ, Srajer V, Sayyed B, Groelzer T, Elliott SJ, Schmidt M, Pacheco AA. “Laue crystal structure of Shewanella oneidensis cytochrome c nitrite reductase from a high-yield expression system”, Journal of Biological Inorganic Chemistry, 2012, 17(4), 674-662. [PDF]

23. Pulcu GS,  Frato KE, Gupta R, Hsu H.-R., Levine GA, Hendrich MP, Elliott SJ. “The Cytochrome c Peroxidase from Shewanella oneidensis Requires Reductive Activation,” Biochemistry, 2012, 52: 974-985. [ PDF ]

2011

22. Hamill, M.J.; Jost, M.; Wong, C.Y.; Elliott, S.J.; Drennan, C.L. “Flavin Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB,” Biochemistry, 2011, 51: 10159-10169. [ PDF ]

21. Levin, B.D.; Can, M.; Bren, K.L.; Elliott, S.J. “Methionine Lability in Bacterial Monoheme Cytochromes c: an electrochemical study,” Journal of Physical Chemistry – B, 2011, 11718-11726. [ PDF ]

20. Firer-Sherwood, M.A.; Ando, N.; Drennan, C.L.; Elliott, S.J. “Solution-based Structural
Analysis of the Decaheme Cytochrome MtrA, by Small Angle X-Ray Scattering and Analytical Ultracentrifugation,” J. Phys. Chem.  – B, 2011, 11208-1114. [PDF]

19. Ellis, K.E.; Seidel, J.; Einsle, O.; Elliott, S.J. “Geobacter sulfurreducens Cytochrome c Peroxidases: electrochemical classification of catalytic mechanisms,” Biochemistry, 2011, 51: 4513-4520. [PDF]

18. Firer-Sherwood, M.A.; Bewley, K.D.; Mock, J.Y.; Elliott, S.J. “Tools for Resolving Complexity in the Electron Transfer Networks of Multiheme Cytochromes” Metallomics, 2011, 3:344-348. [PDF]

2010

17. Cong, H.; Becker, C.F.; Elliott, S.J.; Grinstaff, M.W.; Porco, J.A. “Silver Nanoparticle-Catalyzed Diels-Alder Cycloadditions of 2’-Hydroxychalcones”. J. Am. Chem. Soc. 2010, 132:7514-7518. [PDF]

2009

16. Bak, D.W.; Zuris, J.A.; Paddock, M.; Jennings, P.A.; Elliott, S.J.  “Redox Characterization of the FeS Protein MitoNEET and impact of thiazolidinedione drug binding.” Biochemistry 2009, 48(43):10193-5. [PDF]

15.  Mitra, S.; Elliott, S.J. “Oxidative Disassembly of the [2Fe-2S] Cluster of Human Glutaredoxin 2 and Redox Regulation in the Mitochrondria.” Biochemistry 2009, 48(18):3813-3815. [PDF]

14. Becker, C.F.; Watmough, N.J.; Elliott, S.J. “Electrochemical Evidence for Multiple Peroxidatic Heme States of the Diheme Cytochrome c Peroxidase of Pseudomonas aeruginosa.Biochemistry 2009, 48(1):87-95.[PDF]

2008

13. Hamill, M.J.; Chobot, S.E.; Hernandez, H.H.; Drennan, C.L.; Elliott, S.J. m”Direct Electrochemical Analyses of a Thermophilic Thioredoxin Reductase: interplay between conformational change and redox chemistry.” Biochemistry 2008, 47(37):9738-9746. [PDF]

12. Hernandez, H.H.; Jaquez, O.; Hamill, M.J.; Elliott, S.J.; Drennan, C.L.  “Thioredoxin reductase from Thermoplasma acidophilum: a new twist on redox regulation” Biochemistry 2008, 47(37):9728-9737. [PDF]

11. Firer-Sherwood, M.; Pulcu, G.S.; Elliott, S.J. “Electrochemical interrogations of the Mtr cytochromes from Shewanella: opening a potential window.” J. Biol. Inorg. Chem. 2008, 13(6):849-854. [PDF]

10. Ye, T.; Kaur, R.; Senguen, F.T.; Michel, L.V.; Bren, K.L.; Elliott, S.J.  “Methionine ligand lability of type I cytochromes c: detection of ligand loss using protein film voltammetry.” J. Am. Chem. Soc. 2008 130(21):6682-3. [PDF]

2007

9. Michel, L.V.; Ye, T.; Bowman, S.E.; Levin, B.D.; Hahn, M.A.; Russell, B.S.; Elliott, S.J.; Bren, K.L.
“Heme attachment motif mobility tunes cytochrome c redox potential.” Biochemistry 2007 46(42), 11753-60. [PDF]

8.  Ryan, K.S.; Howard-Jones, A.R.; Hamill, M.J.; Elliott, S.J.; Walsh, C.T.; Drennan, C.L.
“Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC.” Proc. Natl. Acad. Sci. USA 2007 104(39), 15311-6. [PDF]

7. Chobot, S.E.; Hernandez, H.H.; Drennan, C.L.; Elliott, S.J.  “Direct Electrochemical Characterization of Archaeal Thioredoxins.” Angew. Chemie 2007, 46(22), 4145-7.

6. Pulcu, G.S.; Elmore, B.L.; Arciero, D.M.; Hooper, A.B.; Elliott, S.J. “Direct electrochemistry of tetraheme cytochrome c-554 from Nitrosomonas europaea: Redox cooperativity and conformational gating” J. Am. Chem. Soc. 2007, 129(7),1838-9. [PDF]

5. Bradley, A.L; Arciero, D.M.; Hooper, A.B.; Elliott, S.J.
“Protonation and inhibition of Cytochrome c Peroxidase from Nitrosomonas europaea“. J. Inorg. Biochem. 2007, 101(1), 1733-39. [PDF]

2006

4. Tarasev, M.; Pinto, A.; Kim, D.; Elliott, S.J.; Ballou, D.P.  “The ‘bridging’ aspartate 178 in phthalate dioxygenase facilitates interactions between the Rieske center and the iron (II)-mononuclear
center”. Biochemistry 2006, 45(34): 10208-16. [PDF]

2005

3. Ye, T.; Kaur, R.; Wen, X.; Bren, K.L. Elliott, S.J. “Redox properties of wild-type and heme-binding loop mutants of bacterial cytochromes c measured by direct electrochemistry”. Inorg. Chem. 2005, 44(24): 8999-9006. [PDF]

2. di Bernardo, D.; Thompson, M.J.; Gardner, T.S.; Chobot, S.E.*; Eastwood, E.L.; Wojtovich,
A.P.; Elliott, S.J.; Schaus, S.E.; Collins, J.J.  “Chemogenomic Profiling on a Genome-wide Scale Using Reverse-Engineered Gene Networks”. Nature-Biotechnology, 2005, 23(3), 377-83.

2004

1. Bradley, A.L.; Chobot, S.E.; Arciero, D.M.; Hooper, A.B.; Elliott, S.J..
“A Distinctive Electrocatalytic Response from the Cytochrome c Peroxidase of Nitrosomonas europaea“. J. Biol. Chem. 2004, 279(14): 13297-13300. [ PDF]