Welcome to the Neurovascular Imaging Laboratory!
We are an imaging lab. We specialize in imaging neuronal, glial, vascular, and metabolic activity in brains of living and behaving experimental animals. We also use stem-cell-derived human neuronal networks. We focus on obtaining high resolution, sensitivity and specificity optical measurements and combine optical imaging with electrophysiological recordings and functional Magnetic Resonance Imaging (fMRI). Our imaging tools help us understand how brain works and goes awry in disease.
Our research is supported by the National Institutes of Health (NIH) including the BRAIN Initiative. We collaborate with many researchers around the globe to advance the NIH agenda to produce “science in pursuit of fundamental knowledge about the nature and behavior of living systems” that would be eventually applied to extend healthy life and to reduce illness and disability.
One of our major research areas is mechanistic underpinning of noninvasive human brain imaging signals. We investigate how specific patterns of microscopic brain activity (and their pathological departures) translate into noninvasive macroscopic observables obtained with fMRI and electro/magnetoencephalography (EEG/MEG). The overarching goal is to develop a single estimation framework for inference of neuronal network activity from multimodal human fMRI/MEG imaging data.