Publications

2021 – 2025

Chasse AY, Bandyadka S, Wertheimer M, Serizier SB, McCall K (2024) Professional phagocytes are recruited for the clearance of obsolete nonprofessional phagocytes in the Drosophila ovary, Frontiers in Immunology, doi: 10.3389/fimmu.2024.1389674.

Bandyadka S, Lebo DPV, Mondragon A, Serizier SB, Peterson JS, Chasse AY, Jenkins VK, Calikyan A, Kwan J, Ortega AJ, Campbell JD, Emili A, McCall K (2024) Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis, bioRxiv, doi: 10.1101/2024.03.12.584558

Liu G*, Bandyadka S*, McCall K (2024) Protocol to analyze 3D neurodegenerative vacuoles in Drosophila melanogaster, STAR Protocols 5: 103017, doi: 10.1016/j.xpro.2024.103017 (*co-first authors).

Dixon C, McCall K (2023) Characterization of female reproductive disturbances post-traumatic injury in Drosophila melanogaster, microPublication Biology, doi: 10.17912/micropub.biology.000883.

Elguero JE*, Liu G*, Tiemeyer K, Bandyadka S, Gandevia H, Duro L, Yan Z, McCall K (2023) Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling, iScience 12: 108052, doi:10.1016/j.isci.2023.108052 (*co-first authors) .

Serizier SB, Peterson JS, McCall K (2022) Non-autonomous cell death induced by the Draper phagocytosis receptor requires signaling through the JNK and SRC pathways, Journal of Cell Science, 135: jcs250134. Selected as a “Research Highlight” J Cell Sci (2022) 135 (20): e135_e2001.

Lebo DPV, McCall K. (2021) Murder on the Ovarian Express: A Tale of Non-Autonomous Cell Death in the Drosophila Ovary, Cells 10(6):1454, doi: 10.3390/cells10061454.

Lebo DPV, Chirn A, Taylor JD, Levan A, Doerre Torres V, Agreda E, Serizier SB, Lord AK, Jenkins VK, McCall K (2021) An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance, G3: Genes, Genomes, Genetics 11(2):jkaa066, doi: 10.1093/g3journal/jkaa066.

2016 – 2020

Yalonetskaya A, Mondragon AA, Hintze ZJ, Holmes S , McCall K (2020) Nuclear degradation dynamics in a non-apoptotic programmed cell death, Cell Death and Differentiation 27:711-724.

Mondragon AA, Yalonetskaya A, Ortega AJ, Zhang Y, Naranjo O, Elguero J, Chung WS, McCall K (2019) Lysosomal machinery drives extracellular acidification to direct non-apoptotic cell death, Cell Reports 27:11-19.

Yalonetskaya A*,Mondragon AA*, Elguero J*, McCall K (2018) I Spy in the Developing Fly a Multitude of Ways to Die, J. Dev. Biol. 6: E26, doi: 10.3390/jdb6040026 (*co-first authors).

Santoso, C.S., Meehan, T.L., Peterson, J.S., Cedano, T.M., Turlo, C.V. and McCall, K (2018) The ABC transporter Eato promotes cell clearance in the Drosophila melanogaster ovary, G3: Genes, Genomes, Genetics 8:833-843.

Serizier, S.B. and McCall, K. (2017) Scrambled eggs: apoptotic cell clearance by non-professional phagocytes in the Drosophila ovary, Frontiers in Immunology, doi: 10.3389/fimmu.2017.01642.

Timmons, A.K., Mondragon, A.A., Meehan, T.L. and McCall, K. (2017) Control of non-apoptotic nurse cell death by engulfment genes in Drosophila, Fly 11:104-111.

Meehan, T.L., Joudi , T.F., Timmons, A.K., Taylor, J.D., Habib, C., Peterson, J.S., Emmanuel, S., Franc, N.C. and McCall K. (2016) Components of the engulfment machinery have distinct roles in corpse processing, PLoS ONE 11: e0158217.

Meehan, T.L., Serizier, S.B., Kleinsorge, S.E. and McCall, K. (2016) Analysis of phagocytosis in the Drosophila ovary, in Oogenesis, Methods in Molecular Biology series vol. 1457, Humana Press, I. Nezis (ed.), pp. 79-95.

Timmons, A.K., Mondragon, A.A., Schenkel, C.E., Taylor, J.D., Moynihan, K.E., Etchegaray, J.I., Meehan, T.L. and McCall, K. (2016) Phagocytosis genes non- autonomously promote developmental cell death in the Drosophila ovary, Proceedings of the National Academy of Sciences USA 113(9):E1246-55.

Etchegaray, J.I., Elguero, E.J., Tran, J., Sinatra, V., Feany, M.B. and McCall, K. (2016) Defective phagocytic corpse processing results in neurodegeneration and can be rescued by TORC1 activation, Journal of Neuroscience 36:3170-83.

2011 – 2015

Meehan, T.L., Kleinsorge, S., Timmons, A.K., Taylor, J., and McCall, K. (2015) Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary, Disease Models and Mechanisms 8: 1603-14.

Peterson, J.S., Timmons, A.K., Mondragon, A.A., and McCall, K. (2015) The end of the beginning: cell death in the germline. Current Topics in Cell and Developmental Biology 114:93-119.

Meehan, T.L., Yalonetskaya, A., Joudi, T. and McCall, K. (2015) Detection of cell death and phagocytosis in the Drosophila ovary, in Drosophila Oogenesis, Methods and Protocols, Methods in Molecular Biology series vol. 1328, Humana Press, D. Bratu and G. McNeil, eds., pp. 191-206.

Perkins, L.A., Holderbaum, L., Tao, R., Hu, Y., Sopko, R., McCall, K., Yang-Zhou, D., Flockhart, I., Binari, R., Shim, H.S., Miller, A., Housden, A., Foos, M., Randkelv, S., Kelley, C., Namgyal, P., Villalta, C., Liu, L.P., Jiang, X., Huan-Huan, Q., Xia, W., Fujiyama, A., Toyoda, A., Ayers, K., Blum, A., Czech, B., Neumuller, R., Yan, D., Cavallaro, A., Hibbard, K., Hall, D., Cooley, L., Hannon, G.J., Lehmann, R,, Parks, A., Mohr, S.E., Ueda, R., Kondo, S., Ni, J.Q., Perrimon, N. (2015) The Transgenic RNAi Project at Harvard Medical School: Resources and Validation, Genetics 201:843-52.

Kongton, K., McCall, K., and Phongdara, A. (2014) Identification of gamma-interferon-inducible lysosomal thiol reductase (GILT) homologues in the fruit fly Drosophila melanogaster, Developmental & Comparative Immunology 44:389-96.

Peterson, J.S. and McCall, K. (2013) Combined inhibition of autophagy and caspases fails to inhibit developmental nurse cell death in the Drosophila ovary, PLoS One 8(9):e76046.

Jenkins, V.J., Timmons, A. K. and McCall, K. (2013) Diversity of cell death pathways: insight from the Drosophila ovary, Trends in Cell Biology, 23:567-74.

McCall, K. and Klein, C., eds. (2013) Necrosis Methods and Protocols, Methods in Molecular Biology vol. 1004, Humana Press.

Timmons, A.K., Meehan, T.L., Gartmond, T.D. and McCall, K. (2013) Use of Necrotic Markers in the Drosophila ovary, in Necrosis Methods and Protocols, Methods in Molecular Biology vol. 1004, Humana Press, McCall, K. and Klein, C., eds., pp. 215-228.

Etchegaray, J.I.*, Timmons, A.*, Klein, A.P., Pritchett, T.L., Welch, E., Meehan, T.L., Li, C. and McCall, K. (2012) Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells, Development 139:4029-4039 (*co-first authors).

Pritchett, T.L. and McCall, K. (2012) Role of the insulin/Tor signaling network in starvation induced programmed cell death during Drosophila oogenesis, Cell Death and Differentiation 19: 1069-79.

Wonglapsuwan, M., Chotigeat, W., Timmons, A. and McCall, K. (2011) Conserved role for Rpl10A in oogenesis progression in the banana prawn Fenneropenaeus merguiensis and Drosophila melanogaster, General and Comparative Endocrinology 173: 356–363.

Tanner, E.A. and McCall, K. (2011) Mitochondrial regulation of cell death in the Drosophila ovary, Autophagy 7:793-4.

Tanner, E.A., Blute, T.A., Brachmann, C.B. and McCall, K. (2011) Bcl-2 proteins and autophagy regulate mitochondrial dynamics during programmed cell death in the Drosophila ovary, Development 138: 327-338. Highlighted article “In This Issue.”

2006 – 2010

McCall, K. (2010) Genetic control of necrosis – another type of programmed cell death, Current Opinion in Cell Biology 22:882-888.

Bakhrat, A.*, Pritchett, T.*, McCall, K. and Abdu, U. (2010) Drosophila Chk2 and p53 proteins induce stage-specific cell death independently during oogenesis, Apoptosis 15:1425-1434 (*co-first authors).

Pritchett, T.L., Tanner, E.A. and McCall, K. (2009) Cracking open cell death in the Drosophila ovary, Apoptosis 14:969-79.

McCall, K., Pritchett, T.L. and Peterson, J.S. (2009) Detection of cell death in Drosophila. Methods in Molecular Biology, Apoptosis Methods and Protocols (P. Erhardt, ed.), 559:343-56.

Bass, B.P., Tanner, E.A., Mateos San Martín, D., Blute, T., Kinser, R.D., Dolph, P.J. and McCall, K. (2009) Cell-autonomous requirement for DNaseII in non-apoptotic cell death, Cell Death and Differentiation 16:1362-71.

Hou, Y.C., Chittaranjan, S., Gonzalez, S., McCall, K. and Gorski, S. (2008) Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila oogenesis, Journal of Cell Biology 182: 1127-1139.

Peterson, J.S. , Bass, B.P., Jue, D., Rodriguez, A., Abrams, J.M. and McCall, K. (2007) Non-canonical cell death pathways function in Drosophila oogenesis, Genesis 45:396-404.

Baum J.S., Arama, E., Steller, H. and McCall, K. (2007) The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis, Cell Death and Differentiation 14:1508-1517.

Bass, B. P., Cullen, K. and McCall, K. (2007) The axon guidance gene lola is required for programmed cell death in the Drosophila ovary, Developmental Biology 304:771-85.

2000 – 2005

Baum, J.S., St. George, J. P. and McCall, K. (2005) Programmed cell death in the germline, Seminars in Cell and Developmental Biology 16:245-59.

McCall, K. (2005) Programmed cell death in development, Seminars in Cell and Developmental Biology 16:213.

McCall, K. (2004) Eggs over easy: cell death in the Drosophila ovary, Developmental Biology 274: 3-14.

McCall, K. and Peterson, J.S. (2004) Detection of apoptosis in Drosophila, Methods in Molecular Biology, vol. 282: Apoptosis Methods and Protocols (H. Brady, ed.), pp. 191-206.

McCall, K., Baum, J.S., Cullen, K. and Peterson, J.S. (2004) Visualizing Apoptosis, Methods in Molecular Biology, vol. 247: Drosophila Cytogenetics Protocols (D. Henderson, ed.) Humana Press, Totowa, NJ, pp.431-442.

Cullen, K. and McCall, K. (2004) Role of cell death in patterning the Drosophila antennal arista, Developmental Biology 275:82-92.

Laundrie, B.*, Peterson, J.S.*, Baum, J.S.*, Chang, J., Fileppo, D., Thompson, S.R. and McCall, K. (2003) Germline cell death is inhibited by P-element insertions disrupting the dcp-1/pita nested gene pair in Drosophila, Genetics 165: 1881-1888. (*co-first authors)

Peterson, J.S. , Barkett, M. and McCall, K. (2003) Stage-specific regulation of caspase activity in Drosophila oogenesis, Developmental Biology 260: 113-123.

Goyal, L., McCall, K., Agapite, J., Hartwieg, E. and Steller, H. (2000) Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function, EMBO Journal 19: 589-597.

pre-2000

Bergmann, A., Agapite, J., McCall, K. and Steller, H. (1998) The Drosophila gene hid is a direct molecular target of ras-dependent survival signaling, Cell 95: 331-341.

McCall, K. and Steller, H. (1998) Requirement for DCP-1 caspase during Drosophila oogenesis, Science 279: 230-234.

McCall, K. and Steller, H. (1997) Facing death in the fly: genetic analysis of apoptosis in Drosophila, Trends in Genetics 13: 222-226.

Song, Z., McCall, K. and Steller, H. (1997) DCP-1, a Drosophila cell death protease essential for development. Science 275: 536-540.

McCall, K. and Bender, W. (1996) Probes for chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression, EMBO Journal 15: 569-580.

McCall, K., O’Connor, M. B. and Bender, W. (1994) Enhancer traps in the bithorax complex mark parasegmental domains, Genetics 138: 387-399.

Perrimon, N., Noll, E., McCall, K. and Brand, A. (1991) Generating lineage-specific markers to study Drosophila development, Developmental Genetics 12: 238-252.

Bier, E., Vaessin, H., Shepherd, S., McCall, K., Barbel, S., Ackerman, L., Carretto, R., Uemura, T., Grell, E. H., Jan, L. Y. and Jan, Y. N. (1989) Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector, Genes and Development 3: 1273-1287