Welcome to the Gouon-Evans Lab!
From Liver Development to Cell Therapy for Liver Diseases:
The Gouon-Evans lab investigates cellular and molecular mechanisms driving liver development, regeneration and cancer. We specifically interrogate the role of progenitor/stem cells and how they share similar molecular signature and functions during these 3 processes using the mouse embryo, the pluripotent stem cell (PSC) differentiation system and human liver cancer specimens.
Projects in the Gouon-Evans lab will lead to a better understanding of the liver development, to the establishment of multi-modular approaches for improving liver regeneration with PSC derivatives, and will reveal the impact of specific cancer stem cells as a target for diagnosis and therapy in liver oncogenesis.