Courses
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ENG BE 209 4 credits.
Undergraduate Prerequisites: high school biology and CAS CH 101 or equivalent - Introduction to the molecular, physical and computational principles of cell function in the context of cutting-edge applications in bioengineering and medicine. Biological concepts include: molecular building blocks, energetics, transport, metabolism, nucleic acids, gene expression and genetics. Applications include bioenergy, synthetic biology, the human-genome project, and gene circuit engineering. The objectives of the labs are to teach basic techniques and instrumentation in bioengineering, to collect and analyze data and to make sound conclusions. Labs emphasize the experimental, problem solving, and analytical skills required in biomedical engineering and research.
ENG BE 400 4 credits.
Undergraduate Prerequisites: (CASMA226) - Globally more than a 100 million people are forcibly displaced from their homes due to conflict, climate change and persecution. Health challenges faced by these displaced persons are complex and multi-faceted. This course will focus on understanding the health challenges of forcibly displaced persons, identifying why existing solutions may not work, and designing robust, effective and context appropriate solutions for these settings.
ENG BE 403 4 credits.
Undergraduate Prerequisites: (CASMA226 & ENGEK307) Junior standing in BME - Signals, systems, and feedback control with an emphasis on biomedical problems, including linear time invariant systems in continuous and discrete time. Laplace and Fourier representations, transfer functions, pole-zero analysis, stability, convolution, sampling. Analytical and computational methods. Cannot be taken for credit in addition to ENG EC 401.
ENG BE 404 4 credits.
Undergraduate Prerequisites: ENG BE 403 and Junior standing in BME - Mathematical analysis of feedback control systems. Frequency domain methods including transfer functions, stability, root locus, frequency response. Controller design. State space approaches. Emphasis on models of biological and biomedical systems. Controllability, observability. Emphasis on models of biological and biomedical systems. Cannot be taken for credit in addition to ENG ME 403, ENG ME 404, or ENG EC 402.
ENG BE 420 4 credits.
Undergraduate Prerequisites: (ENGEK301 & CASMA226 & ENGEK103) - Many vital physiological functions including locomotion,respiration, circulation,and mechanotransduction are mechanical in nature and are linked to forces and deformation. Mechanics is also critical for development of medical devices and instruments. The main goal of this course is to acquaint students with concepts of stress,strain,constitutive laws and their applications to biomechanics of cells and tissues. The focus will be on theoretical developments. The first part of the course is focused on problems of mechanics of deformable solids including extension,bending,buckling and torsion of beams, as well as the concept of cellular tensegrity. The second, and the greater part of the course is focused on the basic concepts of the theory of elasticity. Topics include: vector and tensor algebra and calculus, kinematics of deformation, stress analysis, constitutive equations. In addition to the linear (Hookean)elasticity, non-linear elasticity is also presented to describe mechanical behavior of biological tissues and cells. The last chapter is devoted to basic concepts of linear viscoelasticity, including stress relaxation, creep and hysteresis. Illustrative examples from tissue and cell biomechanics will be given where appropriate. The course will prepare students for advanced courses in traditional fields of solid mechanics (e.g., plasticity and poroelasticity),finite element analysis,as well as emerging fields (e.g., mechanobiology and nanotechnology). Design elements will be included in projects.
ENG BE 424 4 credits. Fall and Spring
Undergraduate Prerequisites: (ENGEK381 & CASMA226 & CASCH102 & CASPY212) - Fundamental laws of thermodynamics and their application to mechanical and chemical processes. Energy, entropy, and kinetic theory. Chemical equilibrium and thermodynamic potentials. Phase transitions and colligative properties. Introduction to statistical thermodynamics. Problems of biomedical interest will be emphasized.
