The Access Observatory is a new public reporting platform for programs that aim to improve access to disease prevention and treatment services in low- and middle-income countries. Programs in the Access Observatory focus on more than just medicines, and include strategies to strengthen health systems and influence patient behaviors. The Access Observatory was created within the scope of Access Accelerated, a collaboration of several large biopharmaceutical companies, in partnership with the World Bank and the Union of International Cancer Control, that aims to advance access to prevention and treatment for non-communicable diseases globally. Program information available through the Access Observatory is authored by program teams and independently reviewed by the Access Observatory team to ensure completeness, clarity, and consistency. The Access Observatory is a reporting mechanism for Access Accelerated, and is also open to all access programs, including those designed and implemented by public and non-profit organizations. The Access Observatory has been designed by and is managed by a team based in the Department of Global Health at the Boston University School of Public Health. More information on the Access Observatory is available at www.accessobservatory.org.