Publications

  1. Mackie EC, Cheng CH, Alibrio M, Rutledge C, Xin H, Chopp M, McCann R, Rosene DL, Yang Q, Zeldich E, Medalla M. Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys. bioRxiv. 2024:2024-11. https://doi.org/10.1101/2024.11.14.623673  
  2. Cheng CH, Guan Y, Chiplunkar VP, Mortazavi F, Medalla ML, Sullivan K, O’Callaghan JP, Koo BB, Kelly KA, Michalovicz LT. Nerve agent exposure and physiological stress alter brain microstructure and immune profiles after inflammatory challenge in a long-term rat model of Gulf War Illness. Brain, Behavior, & Immunity-Health. 2024 Dec 1;42:100878. https://doi.org/10.1016/j.bbih.2024.100878 
  3. Krengel M, Keating D, Chao L, Dugas J, Koo B, Heeren T, Quinn E, Toomey R, Steele L, Klimas N, Samonte F. Characterizing 1991 Gulf War women veterans from the Boston Biorepository and Integrative Network for Gulf War Illness: demographics, exposures, neuroimaging and cognitive outcomes. The Clinical Neuropsychologist. 2024 Apr 15:1-4. https://doi.org/10.1080/13854046.2024.2344263 
  4. Chao LL, Sullivan K, Krengel MH, Killiany RJ, Steele L, Klimas NG, Koo BB. The prevalence of mild cognitive impairment in Gulf War veterans: a follow-up study. Frontiers in Neuroscience. 2024 Jan 22;17:1301066.  https://doi.org/10.3389/fnins.2023.1301066 
  5. Guan Y, Cheng CH, Bellomo LI, Narain S, Bigornia S, Garelnabi M, Scott T, Ordovas JM, Tucker KL, Bhadelia R, Koo BB. APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts. Frontiers in Aging Neuroscience.;15:1285333. https://doi.org/10.3389/fnagi.2023.1285333.
    1. He S, Guan Y, Cheng CH, Moore T, Luebke JI, Killiany R, Rosene DL, Koo BB, Ou Y. Human-to-Monkey Transfer Learning Identifies the Frontal White Matter as Key Determinant for Predicting Monkey Brain Age. Frontiers in Aging Neuroscience.;15:1249415. https://doi.org/10.3389/fnagi.2023.1249415.
    2. Naeser MA, Martin PI, Ho MD, Krengel MH, Bogdanova Y, Knight JA, Hamblin MR, Fedoruk A, Poole LG, Cheng CH, Koo BB. Transcranial Photobiomodulation Treatment:  Significant Improvements in four Ex-Football Players with Possible Chronic Traumatic Encephalopathy. Journal of Alzheimer’s Disease Reports (JADR) 2023, 7(1), 77–105. DOI 10.3233/ADR-220022. 
    3. Guan, Y., Ebrahimzadeh, S.A., Cheng, C.H., Chen, W., Leung, T., Bigornia, S., Palacios, N., Garelnabi, M.O., Scott, T., Bhadelia, R. and Tucker, K.L., 2022. Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. https://doi.org/10.1212/WNL.0000000000200120.
    4. Yang, E., Kim, C.K., Guan, Y., Koo, B.B. and Kim, J.H., 2022. 3D Multi-Scale Residual Fully Convolutional Neural Network for Segmentation of Extremely Large-Sized Kidney Tumor. Computer Methods and Programs in Biomedicine, p.106616. https://doi.org/10.1016/j.cmpb.2022.106616.
    5. Gonuguntla, V., Yang, E., Guan, Y., Koo, B. B., & Kim, J. H. (2022). Brain signatures based on structural MRI: Classification for MCI, PMCI, and AD. Human Brain Mapping. https://doi.org/10.1002/hbm.25820.
    6. Chia-Hsin Cheng, Zeynab Alshelh, Yi Guan, Kimberly Sullivan, Marco L. Loggia, Bang-Bon Koo, Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness, Brain, Behavior, & Immunity – Health, 2021, 18, 100364, https://doi.org/10.1016/j.bbih.2021.100364.
    7. Steele L, Klimas N, Krengel M, Quinn E, Toomey R, Little D, Abreu M, Aenlle K, Killiany R, Koo B-B, Janulewicz P, Heeren T, Clark AN, Ajama J, Cirillo J, Buentello G, Lerma V, Coller JK, Sullivan K. Brain–Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of 1990–1991 Gulf War Veterans in the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study. Brain Sciences. 2021; 11(9):1132. https://doi.org/10.3390/brainsci11091132
    8. D. Keating, C.G. Zundel, M. Abreu, M. Krengel, K. Aenlle, M.D. Nichols, R. Toomey, L.L. Chao, J. Golier, L. Abdullah, E. Quinn, T. Heeren, J.R. Groh, B.B. Koo, R. Killiany, M.L. Loggia, J. Younger, J. Baraniuk, K. Sullivan. Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community. Life Sciences  (IF5.037),  Pub Date : 2021-08-26, DOI: 10.1016/j.lfs.2021.119903
    9. Farris CW, Killiany RJ, O’Donoghue E, et al. The relationship of age and hypertension with cognition and gray matter cerebral blood volume in a rhesus monkey model of human aging [published online ahead of print, 2021 Jul 1]. Behav Neurosci. 2021;10.1037/bne0000472. doi:10.1037/bne0000472
    10. Bhattacharya B, Xiao S, Chatterjee S, et al. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. J Clin Invest. 2021;131(3):e130319. doi:10.1172/JCI130319
    11. Guan Y, Cheng C-H, Chen W, Zhang Y, Koo S, Krengel M, Janulewicz P, Toomey R, Yang E, Bhadelia R, Steele L, Kim J-H, Sullivan K, Koo B-B. Neuroimaging Markers for Studying Gulf-War Illness: Single-Subject Level Analytical Method Based on Machine Learning. Brain Sciences. 2020; 10(11):884. doi:10.3390/brainsci10110884
    12. Cheng CH, Koo BB, Calderazzo S, Quinn E, Aenlle K, Steele L, Klimas N, Krengel M, Janulewicz P, Toomey R, Michalovicz LT, Kelly KA, Heeren T, Little D, O’Callaghan JP, Sullivan K. Alterations in high-order diffusion imaging in veterans with Gulf War Illness is associated with chemical weapons exposure and mild traumatic brain injury. Brain Behav Immun. 2020 Oct; 89:281-290. PMID: 32745586; DOI: 10.1016/j.bbi.2020.07.006;
    13. Zajac L, Koo BB, Tripodis Y, Mian A, Steinberg E, Mez J, Alosco ML, Cervantes-Arslanian A, Stern R, Killiany R. Hippocampal Resting-State Functional Connectivity Patterns are More Closely Associated with Severity of Subjective Memory Decline than Whole Hippocampal and Subfield Volumes. Cereb Cortex Commun. 2020; 1(1):tgaa019. PMID: 32905008
    14. Guo W, Koo BB, Kim JH, Bhadelia RA, Seo DW, Hong SB, Joo EY, Lee S, Lee JI, Cho KR, Shon YM. Defining the optimal target for anterior thalamic deep brain stimulation in patients with drug-refractory epilepsy. J Neurosurg. 2020 May 08; 1-10. PMID: 32384279
    15. Naeser MA, Ho MD, Martin PI, Hamblin MR, Koo BB. Increased Functional Connectivity Within Intrinsic Neural Networks in Chronic Stroke Following Treatment with Red/Near-Infrared Transcranial Photobiomodulation: Case Series with Improved Naming in Aphasia. Photobiomodul Photomed Laser Surg. 2020 Feb; 38(2):115-131. PMID: 31621498
    16. Koo BB, Calderazzo S, Bowley BGE, Kolli A, Moss MB, Rosene DL, Moore TL. Long-term effects of curcumin in the non-human primate brain. Brain Res Bull. 2018 09; 142:88-95. PMID: 29981358
    17. Koo BB, Michalovicz LT, Calderazzo S, Kelly KA, Sullivan K, Killiany RJ, O’Callaghan JP. Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness. Brain Behav Immun. 2018 Jan; 67:42-46. PMID: 28782715
    18. Farrar DC, Mian AZ, Budson AE, Moss MB, Koo BB, Killiany RJ. Retained executive abilities in mild cognitive impairment are associated with increased white matter network connectivity. Eur Radiol. 2018 Jan; 28(1):340-347. PMID: 28695358
    19. Drew DA, Koo BB, Bhadelia R, Weiner DE, Duncan S, la Garza MM, Gupta A, Tighiouart H, Scott T, Sarnak MJ. White matter damage in maintenance hemodialysis patients: a diffusion tensor imaging study. BMC Nephrol. 2017 Jul 05; 18(1):213. PMID: 28676035
    20. Bauer CM, Zajac LE, Koo BB, Killiany RJ, Merabet LB. Age-related changes in structural connectivity are improved using subject-specific thresholding. J Neurosci Methods. 2017 Aug 15; 288:45-56. PMID: 28647426 
    21. Zajac L, Koo BB, Bauer CM, Killiany R, Behalf Of The Alzheimer’s Disease Neuroimaging Initiative. Seed Location Impacts Whole-Brain Structural Network Comparisons between Healthy Elderly and Individuals with Alzheimer’s Disease. Brain Sci. 2017 Apr 06; 7(4). PMID: 28383490; DOI: 10.3390/brainsci7040037;
    22. Bauer CM, Hirsch GV, Zajac L, Koo BB, Collignon O, Merabet LB. Multimodal MR-imaging reveals large-scale structural and functional connectivity changes in profound early blindness. PLoS One. 2017; 12(3):e0173064. PMID: 28328939; DOI: 10.1371/journal.pone.0173064;
    23. Corinna M. Bauer, Lauren E. Zajac, Bang-Bon Koo, Ronald J. Killiany, Lotfi B. Merabet. Age-related changes in structural connectivity are improved using subject-specific thresholding. Journal of Neuroscience Methods. 2017; 288:45-56.
    24. McKenna F, Koo BB, Killiany R. Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study. Brain Imaging Behav. 2016 Dec; 10(4):970-983. PMID: 26409470
    25. Naeser MA, Martin PI, Ho MD, Krengel MH, Bogdanova Y, Knight JA, Yee MK, Zafonte R, Frazier J, Hamblin MR, Koo BB. Transcranial, Red/Near-Infrared Light-Emitting Diode Therapy to Improve Cognition in Chronic Traumatic Brain Injury. Photomed Laser Surg. 2016 Dec; 34(12):610-626. PMID: 28001756; DOI: 10.1089/pho.2015.4037;
    26. Won YI, Chung CK, Kim CH, Park CK, Koo BB, Lee JM, Jung HW. White Matter Change Revealed by Diffusion Tensor Imaging in Gliomas. Brain Tumor Res Treat. 2016 Oct; 4(2):100-106. PMID: 27867919
    27. He X, Koo BB, Killiany RJ. Edited Magnetic Resonance Spectroscopy Detects an Age-Related Decline in Nonhuman Primate Brain GABA Levels. Biomed Res Int. 2016; 2016:6523909. PMID: 27660760
    28. Margaret A. Naeser, Paula I. Martin, Michael D. Ho, Maxine H. Krengel, Yelena Bogdanova, Jeffrey A. Knight, Megan K. Yee, Ross Zafonte, Bang-Bon Koo, John G. Roubil, Michael R. Hamblin. Handbook of LLLT, chap. 39. Low Level Light Therapy for Rehabilitation in Traumatic Brain Injury and Stroke, including Chronic Aphasia. Pan Stanford Publishing (in press). 2016.
    29. Margaret A Naeser, Paula I Martin, Michael D Ho, Maxine H Krengel, Yelena Bogdanova, Jeffrey A Knight, Megan K Yee, Ross Zafonte, Judith Frazier, Michael R Hamblin, Bang-Bon Koo. Red/near-infrared light-emitting diode therapy for traumatic brain injury. Invited Paper, Proc. SPIE 9467, Micro- and Nanotechnology Sensors, Systems, and Applications VII, 94670M (May 22, 2015); doi:10.1117/12.2176345. 2015. View Publication
    30. Farr OM, Fiorenza C, Papageorgiou P, Brinkoetter M, Ziemke F, Koo BB, Rojas R, Mantzoros CS. Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2529-38. PMID: 25279500; PMCID: PMC4255115; DOI: 10.1210/jc.2014-2774;
    31. Bauer CM, Heidary G, Koo BB, Killiany RJ, Bex P, Merabet LB. Abnormal white matter tractography of visual pathways detected by high-angular-resolution diffusion imaging (HARDI) corresponds to visual dysfunction in cortical/cerebral visual impairment. J AAPOS. 2014 Aug; 18(4):398-401. PMID: 25087644; PMCID: PMC4150820; DOI: 10.1016/j.jaapos.2014.03.004;
    32. Koo BB, Oblak AL, Zhao Y, Farris CW, Bowley B, Rosene DL, Killiany RJ. Hippocampal network connections account for differences in memory performance in the middle-aged rhesus monkey. Hippocampus. 2013 Dec; 23(12):1179-88. PMID: 23780752; PMCID: PMC4113965; DOI: 10.1002/hipo.22156;
    33. Koo BB, Bergethon P, Qiu WQ, Scott T, Hussain M, Rosenberg I, Caplan LR, Bhadelia RA. Clinical prediction of fall risk and white matter abnormalities: a diffusion tensor imaging study. Arch Neurol. 2012 Jun; 69(6):733-8. PMID: 22332181; DOI: 10.1001/archneurol.2011.2272;
    34. Kim CH, Chung CK, Koo BB, Lee JM, Kim JS, Lee SK. Changes in language pathways in patients with temporal lobe epilepsy: diffusion tensor imaging analysis of the uncinate and arcuate fasciculi. World Neurosurg. 2011 Mar-Apr; 75(3-4):509-16. PMID: 21600505; DOI: 10.1016/j.wneu.2010.11.006;
    35. Yoon B, Shim YS, Hong YJ, Koo BB, Kim YD, Lee KO, Yang DW. Comparison of diffusion tensor imaging and voxel-based morphometry to detect white matter damage in Alzheimer’s disease. J Neurol Sci. 2011 Mar 15; 302(1-2):89-95. PMID: 21168157; DOI: 10.1016/j.jns.2010.11.012;
    36. Koo BB, Schettler SP, Murray DE, Lee JM, Killiany RJ, Rosene DL, Kim DS, Ronen I. Age-related effects on cortical thickness patterns of the Rhesus monkey brain. Neurobiol Aging. 2012 Jan; 33(1):200.e23-31. PMID: 20801549; DOI: 10.1016/j.neurobiolaging.2010.07.010;
    37. Koo BBDae-Shik Kim. Computer-based morphometry of brain. International Journal of Imaging Systems and Technology. 2010; 20(2):117-125. View Publication
    38. Koo BB, Choi K, Ronen I, Lee JM, Kim DS. Quantitative mapping of diffusion characteristics under the cortical surface. Magn Reson Imaging. 2010 Oct; 28(8):1175-82. PMID: 20447793; DOI: 10.1016/j.mri.2010.03.020;
    39. Kim CH, Koo BB, Chung CK, Lee JM, Kim JS, Lee SK. Thalamic changes in temporal lobe epilepsy with and without hippocampal sclerosis: a diffusion tensor imaging study. Epilepsy Res. 2010 Jun; 90(1-2):21-7. PMID: 20307957; DOI: 10.1016/j.eplepsyres.2010.03.002;
    40. Choi CH, Lee JM, Koo BB, Park JS, Kim DS, Kwon JS, Kim IY. Sex differences in the temporal lobe white matter and the corpus callosum: a diffusion tensor tractography study. Neuroreport. 2010 Jan 6; 21(1):73-7. PMID: 19996809; DOI: 10.1097/WNR.0b013e3283345eb0;
    41. Shon YM, Kim YI, Koo BB, Lee JM, Kim HJ, Kim WJ, Ahn KJ, Yang DW. Group-specific regional white matter abnormality revealed in diffusion tensor imaging of medial temporal lobe epilepsy without hippocampal sclerosis. Epilepsia. 2010 Apr; 51(4):529-35. PMID: 19817819; DOI: 10.1111/j.1528-1167.2009.02327.x;
    42. Koo BB, Hua N, Choi CH, Ronen I, Lee JM, Kim DS. A framework to analyze partial volume effect on gray matter mean diffusivity measurements. Neuroimage. 2009 Jan 1; 44(1):136-44. PMID: 18775785; DOI: 10.1016/j.neuroimage.2008.07.064;
    43. Koo BBJong-Min LeeJune Sic KimJun Sung ParkJun Soo KwonSun I. Kim. International Journal of Imaging Systems and Technology. Assessing spatial probabilistic distributional differences in the common space between schizophrenics and normal controls based on a novel automated probabilistic pattern analysis method. 2008; 18(5-6):310-324. View Publication
    44. Bang-Bon Koo ; Jong-Min Lee ; June-Sic Kim ; In-Young Kim ; Jun-Soo Kwon ; Sun I. Kim. Fully automatic hybrid registration method based on point feature detection without user intervention. Proc. of SPIE. 2006; 6144:61442N1~8. View Publication
    45. Koo BB, Lee JM, Kim HP, Shin YW, Kim IY, Kwon JS, Kim SI. Representative brain selection using a group-specific tissue probability map. Magn Reson Imaging. 2005 Sep; 23(7):809-15. PMID: 16214612
    46. Yoon U, Lee JM, Koo BB, Shin YW, Lee KJ, Kim IY, Kwon JS, Kim SI. Quantitative analysis of group-specific brain tissue probability map for schizophrenic patients. Neuroimage. 2005 Jun; 26(2):502-12. PMID: 15907307
    47. Kim HP, Lee JM, Lee DS, Koo BB, Kim JJ, Kim IY, Kwon JS, Yoo TW, Chang KH, Kim SI. Development of a group_specific average brain atlas: a comparison study between Korean and Occidental groups. J Biomed Eng Res. 2005; 26:7-13. View Publication
    48. Lee JS, Lee DS, Kim YK, Kim JS, Lee JM, Koo BB, Kim JJ, Kwon JS, Yoo TW, Chang KH, Kim SI, Kang H, Kang E, Chung JK, Lee MC. Quantification of Brain Images Using Korean Standard Templates and Structural and Cytoarchitectonic Probabilistic Maps. Korean J Nucl Med. 2004; 38(3):241-252. View Publication
    49. Koo BB, Lee JM, Kim JS, Lee JS, Kim IY, Kim JJ, Lee DS, Kwon JS, Kim SI. Developing a Korean Standard Brain Atlas on the basis of Statistical and Probabilistic Approach and Visualization tool for Functional image analysis. Korean J Nucl Med. 2003; 37(3):162-170. View Publication
    50. Jong-Min Lee, Bang-bon Koo, Sang-Min Lee, In-Young Kim, Sun I. Kim. a novel automatic algorithm for selecting a standard brain in a data set Set using simple structure analysis in talairach coordinate system. Journal of Digital Imaging. 2003; 16(S1):95-6. View Publication