Research Team


Left to right (in circle): Kristen Hahn (Post-doctoral fellow), Elizabeth Hatch (Co-investigator), Lauren Wise (Principal Investigator), Kenneth Rothman (Co-investigator), Craig McKinnon (Biostatistician), and Alexandra “Lexi” Kriss.

PRESTO is funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and conducted by researchers at Slone Epidemiology Center at Boston University and the Boston University School of Public Health (BUSPH).

Investigative Team

Dr. Lauren A. Wise is Professor of Epidemiology at the Boston University School of Public Health (BUSPH) and Senior Epidemiologist at the Slone Epidemiology Center at Boston University.  She is originally from Canada. She joined the BUSPH Department of Epidemiology in 2004 after completing her doctorate at the Harvard School of Public Health.  Dr. Wise teaches Reproductive Epidemiology and Design and Conduct of Cohort Studies at BUSPH.  She has an interest in reproductive and perinatal epidemiology. Her current research involves the study of risk factors for benign gynecologic conditions, delayed conception, and adverse pregnancy outcomes. Dr. Wise is Co-investigator of the Black Women’s Health Study (BWHS), a nationwide follow-up study of 59,000 African-American women. Dr. Wise is Principal Investigator of NIH-funded studies examining the influence of diet, genetics, and psychosocial factors on the risk of uterine fibroids in the BWHS. Over the past 7 years, Dr. Wise has been collaborating with Drs. Hatch and Rothman on the Snart Gravid and Snart Foraeldre studies, on which she has investigated the associations of physical activity, obesity, and menstrual characteristics with fertility. Dr. Wise is Principal Investigator of PRESTO.

 Tizzy HatchDr. Elizabeth Hatch is Professor of Epidemiology at BUSPH.  Dr. Hatch teaches Cancer Epidemiology at BUSPH and her research focuses on prenatal and childhood exposures in relation to long-term health outcomes, especially hormonally-related cancers, reproductive outcomes, and obesity. Prior to joining the faculty at BU in 2000, she was an investigator at the National Cancer Institute, where she led a large cohort study on the health risks of exposure to the synthetic hormone, diethylstilbestrol (DES) among women exposed during pregnancy and their offspring exposed in utero.  She continues her involvement with the DES study as a co-investigator, and is researching whether DES can affect age at menarche, menopause and obesity among prenatally-exposed women. Currently, Dr. Hatch is principal investigator of a 5-year NIH-funded grant that is a collaborative study of factors related to reproductive health in Denmark (Snart Foraeldre).  Like PRESTO, the study uses internet-based recruitment and follow-up and is evaluating factors related to fertility, miscarriage, and adverse pregnancy outcomes.  Dr. Hatch is Co-investigator of PRESTO, and Principal Investigator of the Snart Gravid and Snart Foraeldre studies after which PRESTO is modeled.

Kenneth RothmanDr. Kenneth J. Rothman is Professor of Epidemiology at BUSPH and Vice President for epidemiology research in RTI Health Solutions.  He has more than 30 years professional experience in epidemiologic research. His recent research has included work on the teratogenicity of vitamin A, the health effects of cellular telephone use, and potential environmental risk factors for cancer.  He has also conducted epidemiologic research on the epidemiology of cancer, cardiovascular disease, birth defects, environmental epidemiology, and methodologic, conceptual and ethical issues in epidemiology.  Dr. Rothman authored two widely used textbook of epidemiologic methods, Modern Epidemiology and Epidemiology: an Introduction, and is the founding editor of Epidemiology, a leading public health journal. He received the American Public Health Association’s Abraham Lilienfeld Award for 2002, recognizing excellence in the teaching of epidemiology during the course of a career, is a Fellow of the International Society for Pharmacoepidemiology, and an honorary fellow of the American College of Epidemiology. Dr. Rothman is Co-investigator of PRESTO.

Ellen MikkelsenDr. Ellen M. Mikkelsen is Senior Researcher in the Department of Clinical Epidemiology at the Aarhus University Hospital in Denmark. Her Ph.D. work focused on the psycho-social consequences of genetic counseling for hereditary breast and ovarian cancers. Dr. Mikkelsen is also trained as a nurse, with experience in intensive care, and has been teaching and tutoring for several years within the field of clinical epidemiology and quality development in the health services. Dr. Mikkelsen has been collaborating with researchers at Boston University on the Snart Gravid and Snart Foraeldre studies, two internet-based studies of women and fertility in Denmark. Like PRESTO, those studies were designed to identify risk factors associated with women’s fertility.  The project also examines whether internet-based questionnaires are useful for collecting scientific data. Dr. Mikkelsen first-authored the main publication describing the methods of the Snart Gravid study in the International Journal of Epidemiology. Her recent work focuses on the effects of oral contraceptives and alcohol on fertility.

Henrik Toft SørensenDr. Henrik Toft Sorensen is Professor of Clinical Epidemiology and is founder of the Department of Clinical Epidemiology at Aarhus University, Denmark, which was established in 2000. Henrik Toft Sørensen is head of the department and since 2004 has been adjunct professor of epidemiology at Boston University. He is furthermore Visiting Professor at Stanford University and Editor of Clinical Epidemiology. His research interests involve investigating the safety of medical interventions, in particular drugs and procedures. Dr. Sørensen has a long history of collaboration with Boston University investigators. He is Co-investigator of the Snart Gravid and Snart Foraeldre time-to-pregnancy studies being conducted in Denmark, studies after which PRESTO is modeled. His recent work focuses on studying the effects of medications such as non-steroidal anti-inflammatory drugs and the risk of miscarriage.

Please also visit the Other Research Staff page to see the other members of the PRESTO team.

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