What is the GWIC?

The Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP)‘s  Gulf War Illness Research Program (GWIRP) announced in 2013 that investigators at two institutions have been selected to create and manage two consortia investigating key aspects of Gulf War Illness.  Dr. Kimberly Sullivan at the Boston University School of Public Health (BUSPH) is head of one consortium and Dr. Mariana Morris at Nova Southeastern University is head of the second.

What is Gulf War Illness?

Gulf War Illness (GWI) is a disorder characterized by multiple persistent symptoms such as chronic headaches, widespread pain, cognitive difficulties, debilitating fatigue, gastrointestinal problems, respiratory symptoms, and other abnormalities that are not explained by traditional medical diagnoses or post-traumatic stress disorder. This complex set of chronic symptoms may affect as many as 200,000 to 250,000 veterans of the 1990-1991 Gulf War, out of the nearly 700,000 deployed to that region.

The two new consortia will conduct pre-clinical and clinical trials research at several leading universities, Veteran’s Administration treatment facilities and civilian hospitals. Because the two consortia share several key investigators, they will be able to build synergy between the investigators, capitalizing on expected as well as unanticipated results. Similar models and methods can also be expected to uncover complementary findings from the varied perspectives of the two consortia.
This website features information regarding only the consortium led by Dr. Kimberly Sullivan. For information on Dr. Mariana Morris’ consortium, see the Additional Links tab.

 Published News Articles on the consortium:

Boston University news article “Gulf War Illness: New Report Lauds Treatment Research, Confirms Toxic Causes

Boston University news article “Closing in on a Medical Mystery

Boston University news article “Helping Veterans with Injuries You Can’t See

Published Studies on Gulf War Illness by researchers in the consortium:

Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness.

Multiple Mild Traumatic Brain Injuries Are Associated with Increased Rates of Health Symptoms and Gulf War Illness in a Cohort of 1990-1991 Gulf War Veterans.

Neuropsychological characteristics of Gulf War illness: A meta-analysis. 

Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness.

Pharmacologically increasing microtubule acetylation corrects stress-exacerbated effects of organophosphates on neurons.

Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness. 

Screening for novel central nervous system biomarkers in veterans with Gulf War Illness. 

Long title: Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness.