MULTITUDE

The Multi-study Data Resource for Diabetes Research (MULTITUDE) is a recently established harmonization of 17 cohort studies and clinical trials that aims to facilitate a better understanding of the determinants, risk factors, and outcomes of T2DM. The main objectives of this project are to determine the lifetime risk of T2DM and the major risk factors, the transition-specific risk from T2DM diagnosis through intermediate morbidity to mortality and to determine the spatiotemporal patterns of T2DM and related morbidity and mortality in these cohorts.

Please see below for the overview of DCC.

Data sets Study type Sample size (N) Follow up time Enrolled Diabetics (N)
ACCORD Clinical trial 10,251 4 to 8 years 10,251
AFFIRM Clinical trial 4,060 5 years 813
BARI 2D Clinical trial 2,368 5 years 2,368
ARIC Prospective cohort 15,792 5 exams to date 3,431
JHS Prospective cohort 5,302 3 exams to date 372
FHS-cohort Prospective cohort 5,209 32 exams to date 199
FHS-offspring Prospective cohort 5,124 9 exams to date 92
FHS-gen3 Prospective cohort 4,095 2 exams to date 96
FOCUS Clinical trial 2,016 60 days 508
MRFIT Clinical trial 12,866 6-8 years 345
ALLHAT Clinical trial

 

33,357;

10,355

4-8 years

 

15,283
BHS Prospective cohort 11,796 7 exams to date 9,037
CORAL Clinical trial 947 31-55 months 310
NGHS Prospective cohort 2,379 9 years 0
OMNI Heart Clinical trial 164 18 weeks 4
POWER-UP Clinical trial 390 24 months 84
SPRINT-POP Clinical trial 9,361 3.26 years 47