MULTITUDE
The Multi-study Data Resource for Diabetes Research (MULTITUDE) is a recently established harmonization of 17 cohort studies and clinical trials that aims to facilitate a better understanding of the determinants, risk factors, and outcomes of T2DM. The main objectives of this project are to determine the lifetime risk of T2DM and the major risk factors, the transition-specific risk from T2DM diagnosis through intermediate morbidity to mortality and to determine the spatiotemporal patterns of T2DM and related morbidity and mortality in these cohorts.
Please see below for the overview of DCC.
Data sets | Study type | Sample size (N) | Follow up time | Enrolled Diabetics (N) |
---|---|---|---|---|
ACCORD | Clinical trial | 10,251 | 4 to 8 years | 10,251 |
AFFIRM | Clinical trial | 4,060 | 5 years | 813 |
BARI 2D | Clinical trial | 2,368 | 5 years | 2,368 |
ARIC | Prospective cohort | 15,792 | 5 exams to date | 3,431 |
JHS | Prospective cohort | 5,302 | 3 exams to date | 372 |
FHS-cohort | Prospective cohort | 5,209 | 32 exams to date | 199 |
FHS-offspring | Prospective cohort | 5,124 | 9 exams to date | 92 |
FHS-gen3 | Prospective cohort | 4,095 | 2 exams to date | 96 |
FOCUS | Clinical trial | 2,016 | 60 days | 508 |
MRFIT | Clinical trial | 12,866 | 6-8 years | 345 |
ALLHAT | Clinical trial
|
33,357;
10,355 |
4-8 years
|
15,283 |
BHS | Prospective cohort | 11,796 | 7 exams to date | 9,037 |
CORAL | Clinical trial | 947 | 31-55 months | 310 |
NGHS | Prospective cohort | 2,379 | 9 years | 0 |
OMNI Heart | Clinical trial | 164 | 18 weeks | 4 |
POWER-UP | Clinical trial | 390 | 24 months | 84 |
SPRINT-POP | Clinical trial | 9,361 | 3.26 years | 47 |