Education
Degree Ph.D. in Bioengineering (2014)
Institution University of Utah Salt Lake City, UT
Degree B.S. in Bioengineering (2010)
Institution University of Washington Seattle, WA
Professional Appointments
Institution Boston University/Broad Institute Boston, MA/Cambridge, MA
Department Electrical and Computer Engineering
Title Postdoctoral Researcher
Period 2014 – Present
Publications
Journal Articles
2016 Nicholas Roehner et al., “Sharing structure and function in biological design with SBOL 2.0,” in ACS Synthetic Biology, vol. 5, pp. 498-506, 2016.
Nicholas Roehner, Eric M. Young, Christopher A. Voigt, D. Benjamin Gordon, and Douglas Densmore, “Double Dutch: a tool for designing combinatorial libraries of biological systems,” in ACS Synthetic Biology, vol. 5, pp. 507-517, 2016.
Zhen Zhang et al., “libSBOLj 2.0: a Java library to support SBOL 2.0,” in IEEE Life Sciences Letters, vol. 1, pp. 34-37, 2016.
Tramy Nguyen, Nicholas Roehner, Zach Zundel, and Chris J. Myers, “A converter from the Systems Biology Markup Language to the Synthetic Biology Open Language,” in ACS Synthetic Biology, vol. 5, pp. 479-486, 2016.
2015 Nicholas Roehner, Zhen Zhang, Tramy Nguyen, and Chris J. Myers, “Generating Systems Biology Markup Language models from the Synthetic Biology Open Language,” in ACS Synthetic Biology, vol. 4, pp. 873-879, 2015.
Prashant Vaidyanathan et al., “A framework for genetic logic synthesis,” in Proceedings of the IEEE, vol. 103, pp. 2196-2207, 2015.
Bryan Bartley et al., “Synthetic Biology Open Language (SBOL) 2.0.0,” in Journal of Integrative Bioinformatics, vol. 12, pp. 272, 2015.
Nicholas Roehner et al., “Proposed data model for the next version of the Synthetic Biology Open Language,” in ACS Synthetic Biology, vol. 4, pp. 57-71, 2015.
2014 Nicholas Roehner and Chris J. Myers, “Directed acyclic graph-based technology mapping of genetic circuit models,” in ACS Synthetic Biology, vol. 3, pp. 543-555, 2014.
Nicholas Roehner and Chris. J Myers, “A methodology to annotate Systems Biology Markup Language models with the Synthetic Biology Open Language,” in ACS Synthetic Biology, vol. 3, pp. 57-66, 2014.
Michal Galdzicki et al., “The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology,” in Nature Biotechnology, vol. 32, pp. 545-550, 2014.
Curtis Madsen, Zhen Zhang, Nicholas Roehner, Chris Winstead, and Chris Myers, “Stochastic model checking of genetic circuits,” in ACM Journal of Emerging Technologies in Computing Systems, vol. 11, pp. 23:1-23:21, 2014.
2012 Curtis Madsen, Chris J. Myers, Tyler Patterson, Nicholas Roehner, Jason T. Stevens, and Chris Winstead, “Design and test of genetic circuits using iBioSim,” in Design and Test of Computers, vol. 29, pp. 32-39, 2012.
Book Chapters
2015 Chris Myers et al., “The Synthetic Biology Open Language,” in Computational Methods in Synthetic Biology (Methods in Molecular Biology Series 1244), Mario Marchisio, Ed., New York City, Springer New York, 2015, ch. 11, pp. 323-336.
Curtis Madsen, Chris Myers, Nicholas Roehner, Chris Winstead, and Zhen Zhang, “Efficient analysis methods in synthetic biology,” in Computational Methods in Synthetic Biology (Methods in Molecular Biology Series 1244), Mario Marchisio, Ed., New York City, Springer New York, 2015, ch. 11, pp. 217-257.
Conference Papers
2012 Curtis Madsen, Chris J. Myers, Nicholas Roehner, Chris Winstead, and Zhen Zhang, “Utilizing stochastic model checking to analyze genetic circuits,” in 2012 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), San Diego, CA, 9-12 May 2012, pp. 379-386.
Technical Reports
2015 Bryan Bartley et al., “Synthetic Biology Open Language (SBOL) version 2.0.0,” BioBricks Foundation, BBF RFC 108, 2015, DOI: 1721.1/98369.
2012 Michal Galdzicki et al., “Synthetic Biology Open Language (SBOL) version 1.1.0,” BioBricks Foundation, BBF RFC 87, 2012, DOI: 1721.1/73909.
Awards
2016 2nd Annual Allan Kuchinsky IWBDA Scholarship
Conference Activity
Service
2016 Genetic logic session chair, 8th International Workshop on Bio-Design Automation (IWBDA), Newcastle Upon Type, UK, 16-18 Aug. 2016.
Program committee member, 8th IWBDA, Newcastle Upon Type, UK, 16-18 Aug. 2016.
2015 Synthetic biology session chair, Computational Modeling in Biology Network (COMBINE) 2015, Salt Lake City, UT, 12-16 Oct. 2015.
Program committee member, 7th IWBDA, Seattle, WA, 19-21 Aug. 2015.
Digital biological information panel member, NIST Synthetic Biology Standards Consortium (SBSC) Kick-Off Workshop, Stanford, CA, 31 Mar. 2015.
Talks
2016 “How to remember and revisit many genetic design variants automatically,” 8th IWBDA, Newcastle Upon Tyne, UK, 16-18 Aug. 2016.
“How to remember and revisit many genetic designs automatically,” Synthetic Biology Engineering Research Center (Synberc) Spring 2016 Retreat, Berkeley, CA, 23-24 Mar. 2016.
2015 “Multiplicity of representation in SBOL 2.0,” COMBINE 2015, Salt Lake City, UT, 12-16 Oct. 2015.
“Double Dutch: a tool for designing libraries of variant metabolic pathways,” 7th IWBDA, Seattle, WA, 19-21 Aug. 2015.
“The Synthetic Biology Open Language 2.0,” 7th IWBDA, Seattle, WA, 19-21 Aug. 2015.
2014 “Generating SBML models from SBOL,” COMBINE 2014, Los Angeles, CA, 18-22 Aug. 2014.
“A proposed data model for the next version of the Synthetic Biology Open Language,” 2014 Synthetic Biology: Engineering, Evolution and Design (SEED), London, 14-17 Jul 2014.
2013 “Directed acyclic graph-based technology mapping of genetic circuit models,” 5th IWBDA, London, 12-13 Jul. 2013.
2012 “A methodology to annotate Systems Biology Markup Language Models with the Synthetic Biology Open Language,” Institute of Biological Engineering (IBE) 2012 Wetern Regional Conference, Logan, UT, Oct. 2012.
“A methodology to annotate Systems Biology Markup Language Models with the Synthetic Biology Open Language,” Special Interest Group on Biological Systems Design (BSD-SIG) at the 20th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Long Beach, CA, 13-17 Jul. 2012.
Teaching Experience
Course Computational Synthetic Biology for Engineers
Institution Boston University Boston, MA
Title Co-Instructor
Term Spring 2016
Course Bio-Signal Processing
Institution University of Utah Salt Lake City, UT
Title Teaching Assistant
Term Spring 2012
Research Experience
Institution University of Utah Salt Lake City, UT
Department Bioengineering
Title Research Assistant
Period 2010-2014
Service to Profession
SBOL Developers Group Member, 2011-Present
Editor, 2013-2015
ACS Synthetic Biology Reviewer, 2016
IET Systems Biology Reviewer, 2016
PLoS ONE Reviewer, 2015
Mathematical Biosciences Reviewer, 2015
Professional Skills
Programming Languages Java, JavaScript, MATLAB, Python, C++
Domain-Specific Standards Synthetic Biology Open Language (SBOL), Systems Biology Markup Language (SBML)
Software Development Tools Eclipse, Git, Maven
Database Systems Neo4j
Genetic Engineering Cell Culture, Flow Cytometry, Molecular Cloning