STOP-1
SARS-CoV-2 Transmission Occurrences among Healthcare Personnel (STOP-1) is a retrospective cohort study launched in Boston, Massachusetts in July 2020. The primary aim of this study was to use contact tracing and epidemiological data, supplemented with viral genome sequencing, to understand how and where COVID-19 transmission occurred amongst healthcare personnel at Boston Medical Center.
Aims
1. Measure the contribution of nosocomial transmission among healthcare personnel in the early COVID-19 pandemic.
2. Capture characteristics associated with nosocomial transmission of SARS-CoV-2.
2A. Characterize nosocomial transmission events and the potential contribution from patients with prolonged SARS-CoV-2 PCR positivity.
3. Determine the impact of infection control interventions on nosocomial transmission.
Methods
391 healthcare workers at Boston Medical Center who were tested for SARS-CoV-2 between March 13 and May 5, 2020 were enrolled in STOP-1. Participants completed two study visits for interviewing and COVID-19 serology. Data was collected from interviews and participant records on COVID-19 testing, symptoms, shifts worked, exposures, travel, residences, employment status, shared space use, medical history, substance use, and use of personal protective equipment. Viral sequencing was also performed on samples from participants who tested positive for SARS-CoV-2.
Study status: Enrollment complete
Publications