CryoEM structures of AL amyloid fibrils
Two manuscripts were published last week describing high-resolution 3D structures of light chain amyloid fibrils extracted from patient heart tissue. Swuec and coworkers solved the structure of a fibril derived from a lambda 6-57 light chain using cryo electron microscopy (cryoEM); Radameker and coworkers did the same for a lambda 1-44 light chain. These structures […]