Congratulations to Dylan and Anjaney!
Last month Dylan Dang and Anjaney Shrivastav graduated from the BU Masters in Medical Sciences program after completing their research projects in the Amyloidosis Center.
Dylan’s thesis was on the stability and aggregation of LECT2 protein, which is responsible for ALECT2 amyloidosis. Dylan cloned, expressed and analyzed LECT2 in order to study the effect of a disease-associated polymorphism at residue 40, showing that the valine and isoleucine forms of the protein have similar characteristics.
Anjaney wrote his thesis on the ability of small molecules to stabilize antibody light chains and prevent their aggregation. He also cloned, expressed and analyzed proteins in the lab, in this case sequences associated with AL amyloidosis. His work showed that the small molecules that we have identified will stabilize isolated light chain variable domains derived from the IGLV2-14 gene.
Dylan and Anjaney are both applying to medical school this cycle. Congratulations and good luck to both!