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BMSIP Projects 2024

2024

Project Title PI Intern
Predictive Models for Alzheimer's Disease Risk using Diverse Clinical and Demographic Data Jinying Chen Haochun Huang
Cancer Progression Markers in Melanoma using Multimodal Sequencing Datasets Deborah Lang Shripushkar Ganesh Krishnan
Deep Learning Methods for Cancer Epitranscriptomics Ignaty Leshchiner Xavier Roy
Alcohol Addiction Associated Spatial Gene Expression Characterization in the Brain Phillip Mews Andreea Soica
GPS2-mediated Signaling Crosstalk with Mitochondrial Unfolded Protein Response using ChIPSeq Valentina Perissi Jawahar Mahendran
Characterizing White Adipose Tissue Celltype Lineage Commitment with scRNASeq Nabil Rabhi Akhila Gundavelli
Neuronal Vulnerability in Alzheimer's Disease using snRNASeq Jean-Pierre Roussarie, Anatomy & Neurobiology at BUSM Bhanu Shankar Dhulipalla
Molecular Mechanisms of Aortic Aneurysm using Multimodal Sequencing Datasets Francesca Seta Allison Madsen
Down Syndrome Epigenetics using iPSC-derived Cortical Organoids Ella Zeldich Shreya Nalluri
Bidirectional Encoder Representations Transformer (BERT)-based Microbial Identification Analysis Pipeline Chao Zhang Truman Fogler
Transmission Electron Microsopy Image Curation and Analysis in Chronic Kidney Diseases Chao Zhang Zach Derse
Whole Slide Image Analysis Algorithms in Ovarian and Breast Cancer Chao Zhang Saumya Pothukuchi
Novel Graph-based Model Algorithms for scRNASeq Analysis Chao Zhang Muxi Wang

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BMSIP Projects 2023

2023

Project Title PI Intern
Data Harmonization with Machine Learning in Alzheimer's Disease Jinying Chen Suraj Prabhu
Machine Learning Algorithms for Alzheimer's Progression Risk Prediction Jinying Chen Vijetha Balakundi
In silico Cell Segmentation of Spatial Transcriptomics in Triple Negative Breast Cancer Tumors Ruben Dries ChihWei Fan
Genetics of Super-resilience in Creutzfeldt-Jakob Disease David Harris/Gustav Mostoslavsky Avarind Sundaravadivelu
Mechanisms of Growth and Differentiation of Melanocytes in Melanoma Deborah Lang Khushi Ahuja
Therapeutic Capacity of Extracellular Vesicles after Cortical Injury Tara Moore Sonal Dinesh Khanna
Molecular Mechanisms sirtuin-1 in Aortic Aneurysm Francesca Seta Pooja Paresh Savla
Molecular Mechanisms of Immune Suppression by AhR in Oral and Lung Cancers David Sherr Vinay Kumar Duggineni
Interactive meta-analysis web tool for gene expression-based contextual classification of cellular phenotypes Tuan Leng Tay Krupa Sampat
Understanding the Epigenetic Landscape of Down Syndrome using Cortical Organoids Ella Zeldich Anna McNiff
Markers of Aging in Mouse and Monkey Models of Alzheimer's Disease Chao Zhang Jou-Hsuan Lee
Computational pipeline for a novel single-cell RNASeq protocol Chao Zhang Zedong Lin

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BMSIP Projects 2022

2022

Project Title PI Intern
Building a comprehensive soil metagenome database Jenny Bhatnagar, Department of Biology Daniel Golden
Analyses of brain gene expression and DNA methylation in Alzheimer’s disease model mice - effects of perinatal choline nutrition Jan Krzysztof Blusztajn PhD, Department of Pathology and Laboratory Medicine Navin Ramanan
Graph database representations of clinical and 'omics data Adam Labadorf/Taylor Falk, Department of Neurology, BUSM and Bioinformatics Program Merai Dandouch
scRNAseq analysis of mouse and human neurons to understand early Alzheimer's disease related pathogenesis in the entorhinal cortex Jean-Pierre Roussarie, Anatomy & Neurobiology at BUSM Manas Dhanuka
RNA sequencing and proteomics analysis to identify molecular pathways implicated in the development of aortic aneurysms Dr. Francesca Seta, Vascular Biology Section at the Boston University School of Medicine Kyra Griffin-Mitchell
Characterizing epigenetic changes to study the mechanisms of stem cell driven epithelial tissue regeneration using RNAseq, ATACseq, HiC Dr. Andrey Sharov, Dermatology at the Boston University School of Medicine Go Ogata
Using scRNAseq to investigate the use of mesenchymal stromal-cell derived extracellular vesicles in mitigating pathogenic signaling in human oligocortical spheroids Dr. Ella Zeldich, Anatomy & Neurobiology at Boston University School of Medicine Raghad Yamani
Long non-coding RNA expression in post mortem brains in alcohol use disorder Huiping Zhang, Departments of Psychiatry and Medicine, Section of Biomedical Genetics Janvee Patel

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