The Alani & Wu Lab

Welcome to BU Dermatology! The Alani and Wu laboratory is focused on understanding the molecular basis of melanoma development, progression, and therapeutic resistance. The aim of our lab is to translate basic research findings to better prevention, detection and treatment of melanoma and to directly enhance the lives of patients currently diagnosed with melanoma. 

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  • Alani Lab Barbeque

  • p300 regulation of the MITF promoter in human melanoma cells

  • A375 Melanoma Cells

  • Selective targeting of melanoma cells by the p300 HAT inhibitor, A-485

  • Selective inhibition of human melanoma cell growth by the CoREST inhibitor, Corin