{"id":5,"date":"2020-03-19T11:17:26","date_gmt":"2020-03-19T15:17:26","guid":{"rendered":"https:\/\/sites.bu.edu\/wilsonwong\/wilson-wong-lab\/"},"modified":"2025-01-25T21:37:49","modified_gmt":"2025-01-26T02:37:49","slug":"wilson-wong-lab","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/wilsonwong\/","title":{"rendered":"Medical Applications of Synthetic Biology"},"content":{"rendered":"<p>Genetically engineered mammalian cells represent the next frontier in medicine.\u00a0 Unique to cell-based platforms is their ability to perform highly robust logical operations by sensing and responding to multiple stimuli <em>in vivo<\/em>, which can revolutionize medicine by creating advanced cell and gene therapies, tissues\/organs, vaccines, and diagnostics.\u00a0 However, despite recent advances in genetic engineering and genome editing, the technological barrier to creating user-defined mammalian cell functions remains immense.\u00a0 To obtain the necessary precision required for complex spatiotemporal control of cell function, we are embarking on an ambitious, <em><u>design-driven<\/u><\/em> research program to develop innovative technologies for next-generation therapeutics and diagnostics, with applications in cancer, autoimmunity, vaccines, and diabetes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Genetically engineered mammalian cells represent the next frontier in medicine.\u00a0 Unique to cell-based platforms is their ability to perform highly robust logical operations by sensing and responding to multiple stimuli in vivo, which can revolutionize medicine by creating advanced cell and gene therapies, tissues\/organs, vaccines, and diagnostics.\u00a0 However, despite recent advances in genetic engineering and [&hellip;]<\/p>\n","protected":false},"author":5845,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"page-templates\/news.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/pages\/5"}],"collection":[{"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/users\/5845"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":9,"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":427,"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/pages\/5\/revisions\/427"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/wilsonwong\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}