{"id":58,"date":"2017-06-08T11:20:31","date_gmt":"2017-06-08T15:20:31","guid":{"rendered":"https:\/\/sites.bu.edu\/wilsonlab\/?page_id=58"},"modified":"2023-10-03T14:45:47","modified_gmt":"2023-10-03T18:45:47","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/wilsonlab\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"
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  1. \n
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    1. Werder et al. \u00a0The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.<\/a> The American Journal of Human Genetics<\/em>. 2023 doi:10.1016\/j.ajhg.2023.08.017. PMID: 37734371.<\/span><\/span><\/p>\n<\/li>\n
    2. Kaserman et al. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin deficiency heterozygosity reveals metabolic dysregulation and cellular heterogeneity<\/a>. Cell Reports<\/em>. 41, 111775 2022. PMID: 36476855.<\/span><\/span><\/p>\n<\/li>\n
    3. Abo et al. Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell\u2013derived alveolar epithelium.<\/span> JCI Insight.<\/i> 2022;7(6):e155589. PMID: 35315362<\/span>.\n

      Click for pdf: <\/a>Abo et al. JCI Insight 2022<\/a>.
      \n<\/span><\/span><\/p>\n<\/li>\n

    4. Werder RB et al. Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient iPSC-hepatocytes<\/a>.<\/span> Molecular Therapy.<\/em> Nov 3 2021. PMID: 34217893.\n

      Click for pdf: Werder et al. Mol Ther 2021<\/a><\/span><\/span><\/p>\n<\/li>\n

    5. Heckman RM et al. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.<\/span> Molecular Cell<\/em>. Dec 17 2020. PMID: 33259812.\n

      Click for pdf: Heckman et al. Mol Cell 2021.<\/a><\/span><\/span><\/p>\n<\/li>\n

    6. Huang J et al. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response<\/span><\/a>. Cell Stem Cell<\/em>. Dec 3 2020. PMID: 32979316.\n

      Click for pdf: Huang et al. Cell Stem Cell 2020<\/a><\/span><\/span><\/p>\n<\/li>\n

    7. Kaserman JE et al. A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells<\/span><\/a>. Stem Cell Reports<\/em>. Jul 14 2020. PMID: 32619491.\n

      Click for pdf: Kaserman et al. Stem Cell Reports 2020<\/a><\/span><\/span><\/p>\n<\/li>\n

    8. Kaserman JE et al. Protocol for Directed Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) to a Hepatic Lineage<\/span><\/a>. Methods Mol. Biol<\/em>. 2017. PMID: 28752455.<\/span><\/span><\/p>\n<\/li>\n
    9. Payne JG et. al.\u00a0Multilineage Transduction of Resident Lung Cells in vivo by AAV2\/8 for \u03b11-Antitrypsin Gene Therapy<\/a>\u00a0Molecular Therapy, Methods & Clinical\u00a0Development<\/em>.<\/span> Jun 29 2016. PMID: 27408904
      \n<\/span><\/span><\/span><\/p>\n

      Click for pdf:\u00a0Payne et al. Mol Ther Methods Clin Dev 2016<\/a> <\/span><\/span><\/p>\n<\/li>\n

    10. Wilson AA et. al.\u00a0Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells<\/a>\u00a0Stem Cell Reports<\/em>.<\/span> Apr 2nd 2015. PMCID: <\/span>PMC4437473
      \n<\/span><\/span><\/span><\/p>\n

      Click for pdf:\u00a0Wilson et al. Stem Cell Reports 2015 <\/a><\/span><\/span><\/p>\n<\/li>\n

    11. Wilson AA et. al.\u00a0Lentiviral Delivery of RNAi for In Vivo Lineage-Specific Modulation of Gene Expression in Mouse Lung Macrophages<\/a>\u00a0Molecular Therapy<\/em>.<\/span>\u00a0Feb 2013. PMCID: <\/span>PMC3616534
      \n<\/span><\/span><\/span><\/p>\n

      Click for pdf:\u00a0Wilson et al. Molecular Therapy 2013<\/a> <\/span><\/span><\/p>\n<\/li>\n

    12. Wilson AA et. al.\u00a0Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.<\/a> Journal of Clinical Investigation<\/em>.<\/span>\u00a0Jan 2010<\/span>.PMID:\u00a020038801
      \n<\/span><\/span><\/span><\/p>\n

      Click for pdf:\u00a0Wilson et al. J Clin Invest 2010<\/a> <\/span><\/span><\/p>\n<\/li>\n

    13. Wilson AA et. al.\u00a0Sustained Expression of \u03b11-Antitrypsin after Transplantation of Manipulated Hematopoietic Stem Cells<\/a>\u00a0American Journal of Respiratory Cell Molecular Biology<\/em>.<\/span>\u00a0Aug 2008. PMID:\u00a018323534
      \n<\/span><\/span><\/span><\/p>\n

      Werder et al. \u00a0The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells. The American Journal of Human Genetics. 2023 doi:10.1016\/j.ajhg.2023.08.017. PMID: 37734371. Kaserman et al. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin deficiency heterozygosity reveals metabolic dysregulation and cellular heterogeneity. Cell Reports. 41, 111775 2022. PMID: 36476855. […]<\/p>\n","protected":false},"author":1896,"featured_media":0,"parent":0,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/pages\/58"}],"collection":[{"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/users\/1896"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/comments?post=58"}],"version-history":[{"count":20,"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/pages\/58\/revisions"}],"predecessor-version":[{"id":440,"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/pages\/58\/revisions\/440"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/wilsonlab\/wp-json\/wp\/v2\/media?parent=58"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

      Click for pdf: Am. J. Respir. Cell Mol. Biol. 2008 Wilson<\/a><\/span><\/span><\/p>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"