{"id":1326,"date":"2022-01-26T08:56:54","date_gmt":"2022-01-26T13:56:54","guid":{"rendered":"https:\/\/sites.bu.edu\/vision\/?p=1326"},"modified":"2022-01-26T09:05:34","modified_gmt":"2022-01-26T14:05:34","slug":"1326","status":"publish","type":"post","link":"https:\/\/sites.bu.edu\/vision\/2022\/01\/26\/1326\/","title":{"rendered":"Arousal-based pupil modulation is dictated by luminance"},"content":{"rendered":"<h4 style=\"text-align: justify;\"><i>Scientific Reports (2022)<\/i><br \/>\nJasmine Pan, Michaela Klimova, Joseph McGuire &amp; Sam Ling<\/h4>\n<div class=\"page\" title=\"Page 2\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p style=\"text-align: justify;\"><img loading=\"lazy\" src=\"\/vision\/files\/2022\/01\/41598_2022_5280_Fig4_HTML.png\" alt=\"\" width=\"305\" height=\"190\" class=\"wp-image-1327 alignleft\" srcset=\"https:\/\/sites.bu.edu\/vision\/files\/2022\/01\/41598_2022_5280_Fig4_HTML.png 1486w, https:\/\/sites.bu.edu\/vision\/files\/2022\/01\/41598_2022_5280_Fig4_HTML-636x395.png 636w, https:\/\/sites.bu.edu\/vision\/files\/2022\/01\/41598_2022_5280_Fig4_HTML-1024x637.png 1024w, https:\/\/sites.bu.edu\/vision\/files\/2022\/01\/41598_2022_5280_Fig4_HTML-768x478.png 768w\" sizes=\"(max-width: 305px) 100vw, 305px\" \/>Pupilometry has become a standard measure for assessing arousal state. However, environmental factors such as luminance, a primary dictator of pupillary responses, often vary across studies. To what degree does luminance interact with arousal-driven pupillary changes? Here, we parametrically assessed luminance-driven pupillary responses across a wide-range of luminances, while concurrently manipulating cognitive arousal using auditory math problems of varying difficulty. At the group-level, our results revealed that the modulatory effect of cognitive arousal on pupil size interacts multiplicatively with luminance, with the largest effects occurring at low and mid-luminances. However, at the level of individuals, there were qualitatively distinct individual differences in the modulatory effect of cognitive arousal on luminance-driven pupillary responses. Our findings suggest that pupillometry as a measure for assessing arousal requires more careful consideration: there are ranges of luminance levels that are more ideal in observing pupillary differences between arousal conditions than others.<\/p>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/www.nature.com\/articles\/s41598-022-05280-1.pdf\">Download it here.<\/a><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Scientific Reports (2022) Jasmine Pan, Michaela Klimova, Joseph McGuire &amp; Sam Ling Pupilometry has become a standard measure for assessing arousal state. However, environmental factors such as luminance, a primary dictator of pupillary responses, often vary across studies. To what degree does luminance interact with arousal-driven pupillary changes? Here, we parametrically assessed luminance-driven pupillary responses [&hellip;]<\/p>\n","protected":false},"author":8254,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/posts\/1326"}],"collection":[{"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/users\/8254"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/comments?post=1326"}],"version-history":[{"count":4,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/posts\/1326\/revisions"}],"predecessor-version":[{"id":1334,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/posts\/1326\/revisions\/1334"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/media?parent=1326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/categories?post=1326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.bu.edu\/vision\/wp-json\/wp\/v2\/tags?post=1326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}