{"id":30,"date":"2023-04-06T11:07:12","date_gmt":"2023-04-06T15:07:12","guid":{"rendered":"https:\/\/sites.bu.edu\/vanuytsellab\/?page_id=30"},"modified":"2023-08-31T14:02:36","modified_gmt":"2023-08-31T18:02:36","slug":"research","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/vanuytsellab\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

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Enhance engraftment potential in postnatal hematopoietic stem cells (HSCs) through the modulation of pathways associated with the superior engraftment of human fetal liver HSCs<\/b><\/p>\n

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Spatially profile the <\/b>intact<\/i><\/b> fetal liver HSC niche to dissect the cellular interactions and signaling events that confer engraftment potential<\/b><\/p>\n

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Defining a sickle cell disease-specific hematopoietic stem and progenitor cell (HSPC) signature <\/b>to advance gene editing and transplantation approaches<\/b><\/p>\n

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Characterization of the hematopoietic stem and progenitor cell (HSPC) fraction throughout development and between mobilization regimens<\/b><\/p>\n

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Exploration of a sickle cell disease patient-specific <\/b>iPSC platform as a <\/b>versatile preclinical <\/b>tool to screen\/validate therapies <\/b>across the diverse sickle cell disease patient population<\/b><\/p>\n

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  Enhance engraftment potential in postnatal hematopoietic stem cells (HSCs) through the modulation of pathways associated with the superior engraftment of human fetal liver HSCs   Spatially profile the intact fetal liver HSC niche to dissect the cellular interactions and signaling events that confer engraftment potential   Defining a sickle cell disease-specific hematopoietic stem and […]<\/p>\n","protected":false},"author":16632,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/pages\/30"}],"collection":[{"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/users\/16632"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/comments?post=30"}],"version-history":[{"count":19,"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/pages\/30\/revisions"}],"predecessor-version":[{"id":315,"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/pages\/30\/revisions\/315"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/vanuytsellab\/wp-json\/wp\/v2\/media?parent=30"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}