Publications

2024:

• Kretov DA, Folkes L, Mora-Martin A, Syedah N, Walawalkar IA, Vanyustel K, Moxon S, Murphy GJ, Cifuentes D. The miR-144/Hmgn2 regulatory axis orchestrates chromatin organization during erythropoiesis. Nat Commun 15, 3821 (2024). https://doi.org/10.1038/s41467-024-47982-2

2023:

• Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs AB, Murphy GJ. De novo hematopoiesis from the fetal lung. Blood Adv. 2023 Nov 28;7(22):6898-6912. doi: 10.1182/bloodadvances.2022008347. PMID: 37729429; PMCID: PMC10685174.

2022:

• Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, Dries R, Campbell JD, Belkina AC, Balazs AB, Murphy GJ. Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment. Nat Commun. 2022 Mar 1;13(1):1103. doi: 10.1038/s41467-022-28616-x. PMID: 35232959; PMCID: PMC8888592.
• Vanuytsel K, Yeung AK, Dowrey TW, Murphy GJ, Belkina AC. CPHEN-013: Comprehensive phenotyping of hematopoietic stem and progenitor cells in the human fetal liver. Cytometry A. 2022 Nov;101(11):903-908. doi: 10.1002/cyto.a.24540. Epub 2022 Mar 7. PMID: 35253987.
• Sae-Lee W, McCafferty CL, Verbeke EJ, Havugimana PC, Papoulas O, McWhite CD, Houser JR, Vanuytsel K, Murphy GJ, Drew K, Emili A, Taylor DW, Marcotte EM. The protein organization of a red blood cell. Cell Rep. 2022 Jul 19;40(3):111103. doi: 10.1016/j.celrep.2022.111103. PMID: 35858567; PMCID: PMC9764456.
• Teo WW, Cao X, Wu CS, Tan HK, Zhou Q, Gao C, Vanuytsel K, Kumar SS, Murphy GJ, Yang H, Chai L, Tenen DG. Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation. Commun Biol. 2022 Apr 11;5(1):343. doi: 10.1038/s42003-022-03250-x. PMID: 35411071; PMCID: PMC9001699. 

2020:

• Vanuytsel K, Mithal A, Giadone RM, Yeung AK, Matte TM, Dowrey TW, Werder RB, Miller GJ, Miller NS, Andry CD, Murphy GJ. Rapid Implementation of a SARS-CoV-2 Diagnostic Quantitative Real-Time PCR Test with Emergency Use Authorization at a Large Academic Safety Net Hospital. Med. 2020 Dec 18;1(1):152-157.e3. doi: 10.1016/j.medj.2020.05.001. Epub 2020 May 19. PMID: 32838351; PMCID: PMC7235561.
• Giadone RM, Mithal A, Miller GJ, Matte TM, Yeung AK, Dowrey TW, Werder RB, Miller NS, Andry CD, Vanuytsel K and Murphy GJ. qRT-PCR Platforms for Diagnosing and Reporting SARS-CoV-2 Infection in Human Samples. STAR Protoc. 2020 Sep 18;1(2):100102. doi: 10.1016/j.xpro.2020.100102. Epub 2020 Sep 15. PMID: 32954369; PMCID: PMC7490627. 

2019:

• Steinberg MH, Kumar S, Murphy GJ, Vanuytsel K. Sickle cell disease in the era of precision medicine: looking to the future. Expert Rev Precis Med Drug Dev. 2019;4(6):357-367. doi: 10.1080/23808993.2019.1688658. Epub 2019 Nov 7. PMID: 33015364; PMCID: PMC7531762. 
• Vanuytsel K, Steinberg MH & Murphy GJ. (2019). Recapitulating Hematopoietic Development in a Dish. 10.1007/978-981-13-3672-0_4. 

2018:

• Vanuytsel K, Matte T, Leung A, Naing ZH, Morrison T, Chui DHK, Steinberg MH, Murphy GJ. Induced pluripotent stem cell-based mapping of β-globin expression throughout human erythropoietic development. Blood Adv. 2018 Aug 14;2(15):1998-2011. doi: 10.1182/bloodadvances.2018020560. PMID: 30108108; PMCID: PMC6093724.
• Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison T, Naign ZH, Wang Z, Dai Y, Chui D, Steinberg MH, Sherr DH, Murphy G. “Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells.” Stem Cells, 2018 Jul;36(7):1004-1019. doi: 10.1002/stem.2822. PMCID: PMC6099224

2017:

• Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11;8(4):1076-1085. doi: 10.1016/j.stemcr.2016.12.017. Epub 2017 Jan 19. PMID: 28111279; PMCID: PMC5390092. 

2016:

• Ordovás L, Boon R, Pistoni M, Chen Y, Sambathkumar R, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Raitano S, Verfaillie CM. Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus. J Vis Exp. 2016 Nov 20;(117):54718. doi: 10.3791/54718. PMID: 27911376; PMCID: PMC5226264.

2015:

• Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM. Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition. Stem Cell Reports. 2015 Nov 10;5(5):918-931. doi: 10.1016/j.stemcr.2015.09.004. Epub 2015 Oct 8. Erratum in: Stem Cell Reports. 2018 Feb 13;10 (2):673. PMID: 26455413; PMCID: PMC4649136. 
• Raitano S, Ordovàs L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, Khurana S, Vanuytsel K, Tóth BI, Voets T, Vandenberghe R, Cathomen T, Van Den Bosch L, Vanderhaeghen P, Van Damme P, Verfaillie CM. Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia. Stem Cell Reports. 2015 Jan 13;4(1):16-24. doi: 10.1016/j.stemcr.2014.12.001. Epub 2014 Dec 31. PMID: 25556567; PMCID: PMC4297877. 

2014:

• Vanuytsel K, Cai Q, Nair N, Khurana S, Shetty S, Vermeesch JR, Ordovas L, Verfaillie CM. FANCA knockout in human embryonic stem cells causes a severe growth disadvantage. Stem Cell Res. 2014 Sep;13(2):240-50. doi: 10.1016/j.scr.2014.07.005. Epub 2014 Jul 27. Erratum in: Stem Cell Res. 2020 Apr;44:101763. PMID: 25108529. 
• Cai Q, Bonfanti P, Sambathkumar R, Vanuytsel K, Vanhove J, Gysemans C, Debiec-Rychter M, Raitano S, Heimberg H, Ordovas L, Verfaillie CM. Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells. Stem Cells Transl Med. 2014 Apr;3(4):489-99. doi: 10.5966/sctm.2013-0078. Epub 2014 Feb 3. PMID: 24493854; PMCID: PMC3973709.

2011:

• Roobrouck VD, Vanuytsel K, Verfaillie CM. Concise review: culture mediated changes in fate and/or potency of stem cells. Stem Cells. 2011 Apr;29(4):583-9. doi: 10.1002/stem.603. PMID: 21305670.

2010:

• Roelandt P, Pauwelyn KA, Sancho-Bru P, Subramanian K, Bose B, Ordovas L, Vanuytsel K, Geraerts M, Firpo M, De Vos R, Fevery J, Nevens F, Hu WS, Verfaillie CM. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS One. 2010 Aug 11;5(8):e12101. doi: 10.1371/journal.pone.0012101. PMID: 20711405; PMCID: PMC2920330.