{"id":9226,"date":"2018-08-29T10:15:43","date_gmt":"2018-08-29T14:15:43","guid":{"rendered":"http:\/\/sites.bu.edu\/urbanarch\/?page_id=9226"},"modified":"2019-06-20T13:32:34","modified_gmt":"2019-06-20T17:32:34","slug":"urban-arch-newsletter-18","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/urbanarch\/urban-arch-newsletter-18\/","title":{"rendered":"Newsletter"},"content":{"rendered":"<h3 style=\"text-align: right;\"><span style=\"color: #000000;\">Volume 5, Issue 3<\/span><\/h3>\n<h3 style=\"text-align: right;\"><span style=\"color: #000000;\">July 2018 &#8211; September 2018<\/span><\/h3>\n<hr \/>\n<h1 style=\"font-size: 14px; text-align: center; margin-bottom: 10px;\"><span style=\"color: #000000;\">Check out the current issue of URBAN ARCH News, the quarterly newsletter bringing you news based on the latest URBAN ARCH and related research.<\/span><\/h1>\n<hr \/>\n<h3 style=\"text-align: center;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/urban-arch-expands-sample-collection-and-assessment-methods\/\">URBAN ARCH Expands Sample Collection and Assessment<\/a><\/h3>\n<p style=\"text-align: center;\"><a href=\"\/urbanarch\/files\/2018\/09\/Front-page-collage3.jpg\"><img loading=\"lazy\" width=\"1580\" height=\"457\" class=\"alignnone wp-image-9321 \" src=\"\/urbanarch\/files\/2018\/09\/Front-page-collage3-636x184.jpg\" alt=\"\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Front-page-collage3-636x184.jpg 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Front-page-collage3-768x222.jpg 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Front-page-collage3-1024x296.jpg 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Front-page-collage3.jpg 1129w\" sizes=\"(max-width: 1580px) 100vw, 1580px\" \/><\/a><\/p>\n<p>In this issue of the URBAN ARCH newsletter we will describe our sample collection and testing techniques.<\/p>\n<hr \/>\n<p style=\"text-align: left;\"><span style=\"color: #000000;\"><strong><span style=\"font-family: Arial; font-size: 13px;\"><a title=\"News Archive\" href=\"https:\/\/sites.bu.edu\/urbanarch\/homepage\/news-archive\/\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\">In the News<\/a><\/span><\/strong><\/span><\/p>\n<ul>\n<li style=\"text-align: left;\"><span>New Grant: Congratulations to Drs. Christine Cheng and Andrew Henderson on receiving funding for\u00a0an\u00a0<\/span><a href=\"https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=9613998&amp;icde=40813665\">R61<\/a><span> to characterize the effects of opioid use disorder on host immune function, HIV replication, and HIV latency.<\/span><\/li>\n<li style=\"text-align: left;\"><span>New Grant: Congratulations to Dr. Karsten Lunze on receiving funding for\u00a0an\u00a0<\/span><a href=\"https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=9677852&amp;icde=41082122&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=1&amp;csb=default&amp;cs=ASC&amp;pball=\">R00<\/a><span>\u00a0which will investigate the role of double stigma related to HIV &amp; substance use among HIV-infected people with addictions and its relations to health and health care.<\/span><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"color: #000000;\"><a href=\"\/urbanarch\/files\/2018\/09\/Susie-K.jpg\"><img loading=\"lazy\" src=\"\/urbanarch\/files\/2018\/09\/Susie-K-636x636.jpg\" width=\"130\" height=\"130\" class=\"wp-image-9245 alignleft\" alt=\"\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K-636x636.jpg 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K-150x150.jpg 150w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K-768x768.jpg 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K-1024x1024.jpg 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K-100x100.jpg 100w, https:\/\/sites.bu.edu\/urbanarch\/files\/2018\/09\/Susie-K.jpg 2048w\" sizes=\"(max-width: 130px) 100vw, 130px\" \/><\/a><\/span><\/p>\n<p><strong><span style=\"color: #000000;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/spotlight-on-susie-kim\/\" style=\"color: #000000;\">Spotlight on&#8230;Susie Kim<\/a><\/span><\/strong><\/p>\n<p>In this issue, we interview\u00a0Susie Kim, a Senior Research Project Manager for the Boston ARCH study.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p><strong><span style=\"text-decoration: underline; color: #000000;\"><span><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/\" target=\"_blank\" style=\"color: #000000; text-decoration: underline;\" rel=\"noopener\"><span style=\"font-family: Arial; font-size: 13px;\">On The Ground<\/span><\/a><\/span><\/span><\/strong><\/p>\n<p><span style=\"color: #000000;\">Click on the buttons to see what the URBAN ARCH Cohorts and Cores have been working on.<\/span><\/p>\n<table width=\"100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\" style=\"font-family: arial; color: black; font-size: 12px; vertical-align: middle;\">\n<tbody>\n<tr align=\"center\">\n<td width=\"92\" style=\"vertical-align: middle; text-align: center;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/#admincore\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000000;\"><img loading=\"lazy\" width=\"108\" height=\"30\" title=\"Admin Core\" class=\"alignnone wp-image-1723 size-full\" src=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2014\/04\/Admin-Core1.jpg\" \/><\/span><\/a><\/td>\n<td width=\"92\" style=\"vertical-align: middle; text-align: center;\"><span style=\"color: #000000;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/#bdmcore\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\"><img loading=\"lazy\" width=\"108\" height=\"30\" title=\"BDM Core\" class=\"alignnone wp-image-1725 size-full\" src=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2014\/04\/BDM-Core.jpg\" \/><\/a><\/span><\/td>\n<td width=\"92\" style=\"vertical-align: middle; text-align: center;\"><span style=\"color: #000000;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/#uganda\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\"><img loading=\"lazy\" width=\"108\" height=\"30\" title=\"Uganda Cohort\" class=\"alignnone wp-image-1726 size-full\" src=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2014\/04\/Uganda-Cohort.jpg\" \/><\/a><\/span><\/td>\n<td width=\"92\" style=\"vertical-align: middle; text-align: center;\"><span style=\"color: #000000;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/#russia\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\"><img loading=\"lazy\" width=\"108\" height=\"30\" title=\"Russia Cohort\" class=\"alignnone wp-image-1727 size-full\" src=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2014\/04\/Russia-Cohort.jpg\" \/><\/a><\/span><\/td>\n<td width=\"92\" style=\"vertical-align: middle; text-align: center;\"><span style=\"color: #000000;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-19\/#boston\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\"><img loading=\"lazy\" width=\"108\" height=\"30\" title=\"Boston Cohort\" class=\"alignnone size-full wp-image-1728\" alt=\"\" src=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2014\/04\/Boston-Cohort.jpg\" \/><br \/>\n<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<hr \/>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"color: #000000; text-decoration: underline;\"><span style=\"font-family: Arial; font-size: 13px;\">Article Spotlight<br \/>\n<\/span><\/span><\/strong><\/span><span style=\"color: #000000;\"><span style=\"font-family: Arial; font-size: 13px;\"><em>This section highlights and provides brief summaries of URBAN ARCH research and their clinical significance.<\/em><\/span><\/span><\/p>\n<p><strong>False-positive Diagnoses Provide a Learning Opportunity for HIV Studies in International Settings<\/strong><\/p>\n<p>International HIV studies may present challenges, including accurate assessment of participants\u2019 study entry criteria. URBAN ARCH researchers recently examined why unexpectedly high numbers of study participants were determined to have an undetectable HIV viral load in Russian and Ugandan cohorts who were thought to have HIV and to be antiretroviral therapy (ART)-na\u00efve at study entry. To qualify for the study, Russian participants had provided written documentation of HIV infection and ART-na\u00efve status; similarly, Ugandan participants\u2019 eligibility was confirmed by investigators via a clinic database. However, post-enrollment baseline testing of samples from both cohorts via enzyme-linked immunosorbent assay HIV testing and testing for ART revealed that\u2026<\/p>\n<ul>\n<li>In the Russian cohort, 16% of participants (58\/360) had undetectable viremia; 3% (9\/360) re-tested HIV-seronegative and 4% (13\/360) tested positive for ART.<\/li>\n<li>In the Ugandan cohort, 11% of participants (55\/482) had undetectable viremia; 5% (26\/482) re-tested HIV-seronegative and &lt;1% (4\/482) tested positive for ART.<\/li>\n<\/ul>\n<p><em>Comments<\/em>: Researchers determined that a number of participants in both cohorts did not have HIV. A small proportion of participants in both cohorts had also received ART, although the proportion in the Uganda cohort was less than one percent. Lessons learned include the need for confirmatory HIV testing to substantiate self-report and rapid testing results, and increased scrutiny of medication use among ART-na\u00efve cohorts prior to randomization or initiation of other study procedures.<\/p>\n<p><em>Reference<\/em>: Coleman SM, Gnatienko N, Lloyd-Travaglini CA, et al. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29384717\">False-positive HIV diagnoses: lessons from Ugandan and Russian research cohorts.<\/a> <em>HIV Clin Trials<\/em>. 2018 Feb;19(1):15\u201322.<\/p>\n<p><span style=\"color: #000000;\">Article Spotlight summary by URBAN ARCH editor Katherine Calver, PhD<\/span><\/p>\n<hr \/>\n<p><span style=\"color: #000000;\"><strong><span style=\"font-family: Arial; font-size: 13px;\"><a title=\"Selected Funding Opportunities\" href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/selected-funding-opportunities\/\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\">Selected NIH Notices and Funding Opportunities<\/a><\/span><\/strong><\/span><\/p>\n<ul>\n<li><span><strong>Improving Implementation of Seek, Test, Treat &amp; Retain Strategies among People Who Inject Drugs in Low to Middle Income Countries\u00a0(<a href=\"https:\/\/grants.nih.gov\/grants\/guide\/rfa-files\/RFA-DA-18-017.html\">RFA-DA-18-017<\/a>)<br \/>\n<\/strong>National Institute of\u00a0Drug Abuse<\/span><span><br \/>\nApplication Due Date:\u00a011\/15\/2018\u00a0<\/span><\/li>\n<li><strong>Women &amp; Sex\/Gender Differences in Drug and Alcohol Abuse\/Dependence (<a href=\"https:\/\/grants.nih.gov\/grants\/guide\/pa-files\/PA-18-603.html\">PA-18-603<\/a>)<br \/>\n<\/strong>Requests broad public input and feedback from interested constituents for the development of the fiscal year 2021-2023 Trans-NIH Strategic Plan for HIV and HIV-Related Research.<br \/>\nApplication Due Date: Standard Dates<\/li>\n<\/ul>\n<p><span style=\"color: #000000;\">Click<span>\u00a0<\/span><span style=\"color: #0000ff;\"><a title=\"Selected Funding Opportunities\" href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/selected-funding-opportunities\/\" target=\"_blank\" style=\"color: #0000ff;\" rel=\"noopener\">here<\/a><\/span><span>\u00a0<\/span>for more funding announcements related to HIV and alcohol research.<\/span><\/p>\n<hr \/>\n<p><strong><span style=\"color: #000000;\"><span style=\"font-family: arial; font-size: 13px;\"><a title=\"Events and Conferences\" href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/upcoming-events-and-conferences\/\" target=\"_blank\" style=\"color: #000000;\" rel=\"noopener\">Events and Conferences<\/a><\/span><\/span><\/strong><\/p>\n<p><span style=\"color: #000000;\"><span>Please email\u00a0<a href=\"mailto:Carly.Bridden@bmc.org\">Carly Bridden<\/a>\u00a0if you will be attending any these meetings, so we can connect you with our investigators.<\/span><\/span><\/p>\n<ul>\n<li><strong><a href=\"http:\/\/www.idweek.org\/\">IDWeek Annual Conference on Prevention, Diagnosis, Treatment and Epidemiology of Infectious Diseases<\/a><\/strong>: October 3-7, 2018; San Francisco, CA.<\/li>\n<li><a href=\"http:\/\/www.amersa.org\/\" target=\"_blank\" rel=\"noopener\"><strong>Association for Medical Education and Research in Substance Abuse (AMERSA) Annual National Conference<\/strong><\/a>:\u00a0November 8-10, 2018; San Francisco, CA.<\/li>\n<li><strong><a href=\"http:\/\/www.asam.org\/education\/live-online-cme\/the-asam-annual-conference\">American Society of Addiction Medicine (ASAM)<\/a>:\u00a0<\/strong>April 4-7, 2019; Orlando, FL<strong>.\u00a0<span>Abstract submission deadline: October 5, 2018.<\/span><\/strong><\/li>\n<\/ul>\n<p style=\"margin-bottom: 10px;\"><span style=\"color: #000000;\">Click<span>\u00a0<\/span><span style=\"color: #0000ff;\"><a title=\"Events and Conferences\" href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/upcoming-events-and-conferences\/\" target=\"_blank\" style=\"color: #0000ff;\" rel=\"noopener\">here<\/a><span>\u00a0<\/span><\/span>for more events and conferences.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Volume 5, Issue 3 July 2018 &#8211; September 2018 Check out the current issue of URBAN ARCH News, the quarterly newsletter bringing you news based on the latest URBAN ARCH and related research. URBAN ARCH Expands Sample Collection and Assessment In this issue of the URBAN ARCH newsletter we will describe our sample collection and [&hellip;]<\/p>\n","protected":false},"author":14001,"featured_media":0,"parent":0,"menu_order":225,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/9226"}],"collection":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/users\/14001"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/comments?post=9226"}],"version-history":[{"count":18,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/9226\/revisions"}],"predecessor-version":[{"id":9331,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/9226\/revisions\/9331"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/media?parent=9226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}