{"id":14416,"date":"2025-12-04T11:32:24","date_gmt":"2025-12-04T16:32:24","guid":{"rendered":"https:\/\/sites.bu.edu\/urbanarch\/?page_id=14416"},"modified":"2026-03-20T16:06:04","modified_gmt":"2026-03-20T20:06:04","slug":"newsletter-vol12-iss3","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/urbanarch\/newsletter-vol12-iss3\/","title":{"rendered":""},"content":{"rendered":"<p><img loading=\"lazy\" src=\"\/urbanarch\/files\/2025\/12\/URBAN-ARCH-Newsletter-Header-2.png\" alt=\"\" width=\"1176\" height=\"333\" class=\"alignnone wp-image-14438 size-full\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/URBAN-ARCH-Newsletter-Header-2.png 1176w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/URBAN-ARCH-Newsletter-Header-2-636x180.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/URBAN-ARCH-Newsletter-Header-2-1024x290.png 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/URBAN-ARCH-Newsletter-Header-2-768x217.png 768w\" sizes=\"(max-width: 1176px) 100vw, 1176px\" \/><\/p>\n<hr \/>\n<h3 style=\"text-align: center;\"><span style=\"color: #333333;\"><strong>Check out the current issue of <em>URBAN ARCH News<\/em>, the quarterly newsletter bringing you news on the latest URBAN ARCH and related research.<\/strong><\/span><\/h3>\n<hr \/>\n<h3 style=\"text-align: center;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/meta-hiv-cvd-main-story\/\" rel=\"noopener noreferrer\" target=\"_blank\" data-link-type=\"web\">META HIV CVD: Research on Alcohol and HIV Through the Years<\/a><\/h3>\n<p><a href=\"https:\/\/sites.bu.edu\/urbanarch\/meta-hiv-cvd-main-story\/\"><img loading=\"lazy\" src=\"\/urbanarch\/files\/2025\/12\/rsa-satellite-636x424.png\" alt=\"\" width=\"636\" height=\"424\" class=\"size-medium wp-image-14434 aligncenter\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/rsa-satellite-636x424.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/rsa-satellite-1024x682.png 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/rsa-satellite-768x511.png 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/rsa-satellite.png 1287w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><strong>In this edition of the URBAN ARCH Newsletter, we highlight the META HIV CVD P01 Center, their annual Research on Alcohol and HIV meeting, and look ahead to a newly funded P60 Center.<\/strong><\/p>\n<hr \/>\n<div _mce_style=\"font-family: Arial, Helvetica, sans-serif; font-size: 10pt;\">\n<h3><a href=\"https:\/\/sites.bu.edu\/urbanarch\/updates-from-2nd-generation-urban-arch-hiv-alcohol-p01s-vol12iss3\/\"><strong>Updates from 2nd Generation URBAN ARCH HIV\/Alcohol P01s<\/strong><\/a><\/h3>\n<table class=\" aligncenter\" style=\"border-color: #ffffff; width: 1000px;\">\n<tbody>\n<tr style=\"border-color: #ffffff;\">\n<td style=\"border-color: #ffffff; width: 500px;\"><a href=\"http:\/\/sites.bu.edu\/urbanarch\/updates-from-2nd-generation-urban-arch-hiv-alcohol-p01s-vol12iss3\/#archer\"><img loading=\"lazy\" src=\"\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-636x257.png\" alt=\"\" width=\"245\" height=\"99\" class=\"aligncenter wp-image-12241\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-636x257.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-1024x414.png 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-768x310.png 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-1536x620.png 1536w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/03\/ARCHER_LOGO_color-1-e1648038091984-2048x827.png 2048w\" sizes=\"(max-width: 245px) 100vw, 245px\" \/><\/a><\/td>\n<td style=\"border-color: #ffffff; width: 500px;\"><a href=\"http:\/\/sites.bu.edu\/urbanarch\/updates-from-2nd-generation-urban-arch-hiv-alcohol-p01s-vol12iss3\/#meta\"><img loading=\"lazy\" src=\"\/urbanarch\/files\/2021\/12\/META-HIV-CVD-Microbiome-Metabolites-and-Alcohol-in-HIV-to-reduce-CVD.png\" alt=\"\" width=\"285\" height=\"99\" class=\"aligncenter wp-image-11749\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div _mce_style=\"font-family: Arial, Helvetica, sans-serif; font-size: 10pt;\">\n<hr \/>\n<h3><a href=\"https:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-core-and-project-updates-vol12iss3\/\"><strong>International URBAN ARCH Center Updates<\/strong><\/a><\/h3>\n<\/div>\n<p><span style=\"color: #333333;\">Click on the buttons below to see what the International URBAN ARCH Center Cores and Projects have been working on.<\/span><\/p>\n<table width=\"729\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\" height=\"66\" style=\"border-color: #ffffff; height: 66px;\">\n<tbody>\n<tr align=\"center\">\n<td width=\"92\" style=\"border-color: #ffffff; width: 92px;\"><a href=\"http:\/\/sites.bu.edu\/urbanarch\/core-and-cohort-updates-23\/#admincore\" target=\"_blank\" rel=\"noopener noreferrer\"><span><\/span><\/a><a href=\"https:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-core-and-project-updates-vol12iss3\/#admincore\"><img loading=\"lazy\" width=\"163\" height=\"49\" title=\"Admin Core\" class=\"alignnone wp-image-12700\" alt=\"\" src=\"\/urbanarch\/files\/2022\/09\/admin-core-button-636x190.png\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/admin-core-button-636x190.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/admin-core-button-768x229.png 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/admin-core-button.png 898w\" sizes=\"(max-width: 163px) 100vw, 163px\" \/><\/a><\/td>\n<td width=\"92\" style=\"border-color: #ffffff; width: 92px;\"><a href=\"http:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-updates\/#BDMcore\"><span><\/span><\/a><a href=\"https:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-core-and-project-updates-vol12iss3\/#bdm\"><img loading=\"lazy\" width=\"163\" height=\"49\" title=\"BDM Core\" class=\"alignnone wp-image-12699\" alt=\"\" src=\"\/urbanarch\/files\/2022\/09\/bdm-core-button-636x190.png\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/bdm-core-button-636x190.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/bdm-core-button-768x229.png 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/bdm-core-button.png 898w\" sizes=\"(max-width: 163px) 100vw, 163px\" \/><\/a><\/td>\n<td width=\"92\" style=\"border-color: #ffffff; width: 92px;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-core-and-project-updates-vol12iss3\/#trac\"><img loading=\"lazy\" width=\"166\" height=\"49\" title=\"TRAC Project\" class=\"alignnone wp-image-12698\" alt=\"\" src=\"\/urbanarch\/files\/2022\/09\/trac-button-636x188.png\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/trac-button-636x188.png 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/trac-button-768x227.png 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/trac-button.png 898w\" sizes=\"(max-width: 166px) 100vw, 166px\" \/><\/a><span><\/span><\/td>\n<td width=\"92\" style=\"border-color: #ffffff; width: 92px;\"><a href=\"https:\/\/sites.bu.edu\/urbanarch\/international-urban-arch-center-core-and-project-updates-vol12iss3\/#talc\"><img loading=\"lazy\" width=\"163\" height=\"49\" title=\"TALC Project\" class=\"alignnone wp-image-12701\" alt=\"\" src=\"\/urbanarch\/files\/2022\/09\/talc-button.png\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<h3><a href=\"https:\/\/sites.bu.edu\/urbanarch\/spotlight-on-judy-hahn-phd-ma\/\">Spotlight on&#8230; Judy Hahn, PhD, MA<\/a><\/h3>\n<p><img loading=\"lazy\" src=\"\/urbanarch\/files\/2022\/09\/judy-hahn-workshop-1-570x636.jpg\" alt=\"\" width=\"144\" height=\"160\" class=\" wp-image-12675 alignleft\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/judy-hahn-workshop-1-570x636.jpg 570w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/judy-hahn-workshop-1-918x1024.jpg 918w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/judy-hahn-workshop-1-768x857.jpg 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2022\/09\/judy-hahn-workshop-1.jpg 1200w\" sizes=\"(max-width: 144px) 100vw, 144px\" \/>In this interview, we highlight Judy Hahn and the recently-funded Center for Alcohol\/HIV Innovations and Biomarker Research (<a href=\"https:\/\/reporter.nih.gov\/search\/4JEOrkA7y0qTRsJCOqSmfg\/project-details\/11076975\">CALIBER<\/a>) P60.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3><span style=\"text-decoration: underline;\">Article Spotlight<\/span><\/h3>\n<p><strong>Sex-based Differences in Gut Microbiome Composition and Function Among People with HIV and Risky Drinking<\/strong><\/p>\n<p>Among people with HIV, alcohol use has been shown to contribute to gut dysbiosis, affecting beneficial butyrate-producing bacterial families. Researchers examined sex-based differences in the composition and function of the gut microbiome among 202 adults with HIV and risky alcohol use (\u22655 heavy drinking days in the last month) who were participants in the St PETER HIV trial in St. Petersburg, Russia. Alcohol use was assessed at baseline via self-report and Phosphatidylethanol (PEth) biomarker levels in blood. Fecal samples were provided within 30 days of baseline to assess gut microbiome via 16S rRNA gene sequencing.<\/p>\n<ul>\n<li>Participants were predominantly male (71 percent) and had an average age of 38 years. Average alcohol consumption in the cohort ranged from 4.9 to 108.9 drinks per week in the last month. Participants had no documented antibiotic, prebiotic, or probiotic use in the prior three months.<\/li>\n<li>In adjusted analyses, women in the cohort had significantly greater gut microbiome diversity than men (as assessed via alpha diversity indices, Operational Taxonomic Units, and Shannon Index).<\/li>\n<li>Compared with men, women also had significantly higher percent relative abundance of <em>Firmicutes<\/em> and lower percent relative abundance of <em>Bacteroidota<\/em> and higher <em>Firmicutes<\/em>\/<em>Bacteroidota <\/em> Women also had significantly higher percent relative abundance of beneficial butyrate-producing bacteria.<\/li>\n<li>Women had a lower percent relative abundance of the pathobiont, <em>Prevotellaceae<\/em>.<\/li>\n<\/ul>\n<p><em>Comments<\/em>: This study showed significant sex-based differences in gut microbiome diversity and composition among people with HIV and risky drinking. Microbial gut dysbiosis has been associated with inflammation and other comorbidities; tailored probiotic therapies for improving gut health in people with HIV and alcohol use may help mitigate these negative outcomes.<\/p>\n<p><em>Reference<\/em>: <span>Rao AV, Ghare SS, Gautam V, Hoffman KL, Petrosino J, So-Armah K, Samet JH, Patts GJ, Cheng DM, Blokhina E, Krupitsky EM, Lioznov D, Zvartau E, McClain CJ, Tindle H, Freiberg MS, Barve SS. <\/span><a href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2025.1632949\/full\">Sex differences in beneficial and pathogenic bacteria in People With HIV (PWH) with a history of heavy alcohol drinking<\/a>. <em>Front. Microbiol<\/em>. 2025;16:1632949.<\/p>\n<hr \/>\n<h3><span style=\"text-decoration: underline;\">Register Now: 2026 URBAN ARCH Annual Meeting<\/span><\/h3>\n<p><span>Mark your calendars! The 2026 URBAN ARCH Annual Meeting will be held on Monday, March 30, 2026. Attendees are invited to join us virtually or in-person in Boston. Please click <strong><a href=\"https:\/\/files.constantcontact.com\/36bc81f1401\/377e9f0a-072a-4455-af89-9f768d079844.pdf?rdr=true\">here<\/a> <\/strong>to view the meeting agenda and register <a href=\"https:\/\/forms.office.com\/r\/bKnFHhZuXv\"><strong>here<\/strong><\/a>. We hope to see you there!<\/span><\/p>\n<figure id=\"attachment_13880\" aria-describedby=\"caption-attachment-13880\" style=\"width: 525px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" src=\"\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-636x337.jpg\" alt=\"\" width=\"515\" height=\"273\" class=\" wp-image-13880\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-636x337.jpg 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-1024x542.jpg 1024w, https:\/\/sites.bu.edu\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-768x407.jpg 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-1536x814.jpg 1536w, https:\/\/sites.bu.edu\/urbanarch\/files\/2024\/06\/MED_8092-scaled-e1718295547252-2048x1085.jpg 2048w\" sizes=\"(max-width: 515px) 100vw, 515px\" \/><figcaption id=\"caption-attachment-13880\" class=\"wp-caption-text\"><span>Photo from the 2024 URBAN ARCH Annual Meeting in Boston.<\/span><\/figcaption><\/figure>\n<hr \/>\n<h3><a href=\"https:\/\/sites.bu.edu\/urbanarch\/publications\/\"><strong>New URBAN ARCH Publications<\/strong><\/a><\/h3>\n<ul>\n<li><span>Hahn JA, Kane JC, Fatch R, Espinosa da Silva C, Emenyonu NI, Scheffler A, Chirayil P, So-Armah K, Kahler CW, Conroy AA, Edelman EJ, Woolf-King S, Parry CD, Kiene SM, Chamie G, Muyindike WR, Adong J, Go VF, Cook RL, Morojele NK, Fiellin DA, Santos GM, Tahir P, Samet J, Krupitsky E, Allen IE.\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40992009\/\">Alcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report<\/a><span>.\u00a0<\/span><em>Drug Alcohol Depend<\/em><span>. 2025 Sep 12;276:112879. Epub ahead of print.<\/span><\/li>\n<\/ul>\n<hr \/>\n<h3><a href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/upcoming-events-and-conferences\/\"><span style=\"text-decoration: underline;\"><strong>Events and Conferences<\/strong><\/span><\/a><\/h3>\n<ul>\n<li><strong><a href=\"https:\/\/www.croiconference.org\">Conference on Retroviruses and Opportunistic Infections (CROI)<\/a><\/strong>: February 22-25, 2026; Denver, CO, USA.<\/li>\n<li><a href=\"http:\/\/iwhod.org\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>International Workshop on HIV and Hepatitis Observational Databases<\/strong><\/a><strong>:\u00a0<\/strong>March 26-28, 2026; Thessaloniki, Greece.<\/li>\n<\/ul>\n<p><strong>Upcoming abstract deadlines<\/strong>: 2026 International AIDS Society (January 27, 2026), 2026 Research Society on Alcohol (January 30, 2026)<\/p>\n<p><span>Click<\/span><span>\u00a0<\/span><a href=\"https:\/\/sites.bu.edu\/urbanarch\/resources\/upcoming-events-and-conferences\/\" rel=\"noopener noreferrer\" target=\"_blank\" data-link-type=\"web\">here<\/a><span>\u00a0for more events and conferences.<\/span><\/p>\n<hr \/>\n<h6><img loading=\"lazy\" src=\"\/urbanarch\/files\/2025\/12\/boston-snow-storm-january-2019-t-636x424.jpg\" alt=\"\" width=\"386\" height=\"257\" class=\" wp-image-14430 aligncenter\" srcset=\"https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/boston-snow-storm-january-2019-t-636x424.jpg 636w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/boston-snow-storm-january-2019-t-768x512.jpg 768w, https:\/\/sites.bu.edu\/urbanarch\/files\/2025\/12\/boston-snow-storm-january-2019-t.jpg 900w\" sizes=\"(max-width: 386px) 100vw, 386px\" \/><\/h6>\n<h6 style=\"text-align: center;\">Happy Holidays from URBAN ARCH!<\/h6>\n","protected":false},"excerpt":{"rendered":"<p>Check out the current issue of URBAN ARCH News, the quarterly newsletter bringing you news on the latest URBAN ARCH and related research. META HIV CVD: Research on Alcohol and HIV Through the Years In this edition of the URBAN ARCH Newsletter, we highlight the META HIV CVD P01 Center, their annual Research on Alcohol [&hellip;]<\/p>\n","protected":false},"author":20124,"featured_media":0,"parent":0,"menu_order":206,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/14416"}],"collection":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/users\/20124"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/comments?post=14416"}],"version-history":[{"count":10,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/14416\/revisions"}],"predecessor-version":[{"id":14464,"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/pages\/14416\/revisions\/14464"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/urbanarch\/wp-json\/wp\/v2\/media?parent=14416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}