{"id":170,"date":"2010-07-02T17:47:36","date_gmt":"2010-07-02T21:47:36","guid":{"rendered":"http:\/\/blogs.bu.edu\/ombs\/?p=170"},"modified":"2010-07-02T17:47:36","modified_gmt":"2010-07-02T21:47:36","slug":"this-blog-post-will-make-you-rich","status":"publish","type":"post","link":"https:\/\/sites.bu.edu\/ombs\/2010\/07\/02\/this-blog-post-will-make-you-rich\/","title":{"rendered":"THIS BLOG POST WILL MAKE YOU RICH."},"content":{"rendered":"<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\">Casinos everywhere are packed- with gamblers ranging from newly legal young adults to middle aged women out for a ladies\u2019 night to senior citizens with eyes reflecting the lights of the penny slots.\u00a0 Amongst a sea of others.\u00a0 What could they possibly have in common?\u00a0 Dopamine (DA) receptors, of course!\u00a0 A recent study by Tremblay et al investigated the magnitude of effect DA has on reinforcing gambling tendencies.<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\"><br \/>\n<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\">\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\">When playing a slot machine, players\u2019 tendencies lean towards a pattern of instrumental conditioning.\u00a0 In this way, when a trial returns a sizable payoff, participants are more likely to make a risky bet in the succeeding one.\u00a0 However, when haloperidol (a D2 antagonist) was applied, the correlation between payoff and bet declined.\u00a0 Tremblay cites a previous study (Pessiglione et al. 2006) in which haloperidol was associated with a loss of striatal activation in response to reward related versus non-reward-related stimuli.\u00a0 Redish et al. (2007) proposes that persistent betting involves reactivation of a learned expectancy, the reward, a behavior modulated by DA.\u00a0 It is interesting to note though, that participants in Pessiglione\u2019s experiments reported enhanced pleasurable effects of the game under haloperidol, even while their tendency to bet large sums was decreased.<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\"><br \/>\n<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\"> <\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\">So, how will this information make you money?\u00a0 Well, directly, maybe it won\u2019t.\u00a0 But the next time you make that fateful trip to Atlantic City, keep your dopamine in check.<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"letter-spacing: 0.0px\"><br \/>\n<\/span><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\">\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><a href=\"https:\/\/sites.bu.edu\/ombs\/files\/2010\/06\/Zack-Haloperidol-and-Slot-Machine-Gambling.pdf\">Tremblay et al- Haloperidol and Slot Machine Gambling<\/a><\/p>\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\">\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\">\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\">\n<p style=\"margin: 0.0px 0.0px 0.0px 0.0px;font: 12.0px Helvetica\"><span style=\"font-family: Georgia, 'Times New Roman', 'Bitstream Charter', Times, serif;font-size: small\"><span style=\"line-height: 19px\"><span style=\"font-family: Helvetica;font-size: small\"><span style=\"line-height: normal\"><br \/>\n<\/span><\/span><\/span><\/span><\/p>\n<p><a class=\"addthis_button\" href=\"http:\/\/www.addthis.com\/bookmark.php?v=250&amp;username=xa-4bb6bcc8320e5dd9\"><img loading=\"lazy\" src=\"http:\/\/s7.addthis.com\/static\/btn\/v2\/lg-share-en.gif\" alt=\"Bookmark and Share\" width=\"125\" height=\"16\" \/><\/a><script src=\"http:\/\/s7.addthis.com\/js\/250\/addthis_widget.js#username=xa-4bb6bcc8320e5dd9\" type=\"text\/javascript\"><\/script><br \/>\n<!-- AddThis Button END --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Casinos everywhere are packed- with gamblers ranging from newly legal young adults to middle aged women out for a ladies\u2019 night to senior citizens with eyes reflecting the lights of the penny slots.\u00a0 Amongst a sea of others.\u00a0 What could they possibly have in common?\u00a0 Dopamine (DA) receptors, of course!\u00a0 A recent study by Tremblay [&hellip;]<\/p>\n","protected":false},"author":4162,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/posts\/170"}],"collection":[{"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/users\/4162"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/comments?post=170"}],"version-history":[{"count":0,"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/posts\/170\/revisions"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/media?parent=170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/categories?post=170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.bu.edu\/ombs\/wp-json\/wp\/v2\/tags?post=170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}