{"id":2805,"date":"2025-05-28T10:05:39","date_gmt":"2025-05-28T14:05:39","guid":{"rendered":"https:\/\/sites.bu.edu\/nrl\/?p=2805"},"modified":"2025-05-28T10:05:39","modified_gmt":"2025-05-28T14:05:39","slug":"new-publication-in-npj-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/sites.bu.edu\/nrl\/2025\/05\/28\/new-publication-in-npj-parkinsons-disease\/","title":{"rendered":"New Publication in npj parkinson&#8217;s disease!"},"content":{"rendered":"<p>We\u2019re excited to share our recent publication in npj parkinson&#8217;s disease! Check out more details <a href=\"https:\/\/www.nature.com\/articles\/s41531-025-00952-x\">here<\/a>.<!--more--><\/p>\n<h4><strong><span style=\"color: #993300;\">Title<\/span><\/strong><\/h4>\n<p>Amplifying walking activity in Parkinson\u2019s disease through autonomous music-based rhythmic auditory stimulation: randomized controlled trial<\/p>\n<h4><span style=\"color: #993300;\"><strong>Authors<\/strong><\/span><\/h4>\n<p>F. Porciuncula, J. T. Cavanaugh, J. Zajac, N. Wendel, T. Baker, D. Arumukhom Revi, N. Eklund, M. B. Holmes, L. N. Awad &amp; T. D. Ellis<\/p>\n<h4><span style=\"color: #993300;\"><strong>Abstract<\/strong><\/span><\/h4>\n<p><span>Habitual moderate intensity walking has disease-modifying benefits in Parkinson\u2019s disease (PD). However, the lack of sustainable gait interventions that collectively promote sufficient intensity, daily amount, and quality of walking marks a critical gap in PD rehabilitation. In this randomized controlled trial (clinicaltrials.gov#: NCT05421624, registered on June 6, 2022), we demonstrate the effectiveness of a real-world walking intervention delivered using an autonomous music-based digital rhythmic auditory stimulation (RAS) system. In comparison to an active-control arm (<i>N<\/i>\u2009=\u200920) of moderately intense brisk walking, the autonomous RAS system used in the experimental arm (<i>N<\/i>\u2009=\u200921) amplified moderate-to-vigorous walking intensities, increased daily steps, and improved (reduced) gait variability. While regular engagement in real-world walking with or without RAS each cultivated habits for walking, only the RAS intervention yielded a combination of strengthened habits and improved gait outcomes. Findings from this study supported the use of a personalized, autonomous RAS gait intervention that is effective, habit-forming and translatable to real-world walking in individuals with PD.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>We\u2019re excited to share our recent publication in npj parkinson&#8217;s disease! Check out more details here.<\/p>\n","protected":false},"author":23332,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12,14],"tags":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/posts\/2805"}],"collection":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/users\/23332"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/comments?post=2805"}],"version-history":[{"count":1,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/posts\/2805\/revisions"}],"predecessor-version":[{"id":2806,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/posts\/2805\/revisions\/2806"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/media?parent=2805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/categories?post=2805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/tags?post=2805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}