{"id":1639,"date":"2020-10-14T11:06:25","date_gmt":"2020-10-14T16:06:25","guid":{"rendered":"https:\/\/sites.bu.edu\/nrl\/?page_id=1639"},"modified":"2025-02-14T11:57:19","modified_gmt":"2025-02-14T16:57:19","slug":"reneu","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/nrl\/patient-connect\/reneu\/","title":{"rendered":""},"content":{"rendered":"<h4><span style=\"color: #993300;\"><strong>reNeu: A soft, hybrid <span style=\"text-decoration: underline;\">r<\/span>obotic <span style=\"text-decoration: underline;\">e<\/span>xosuit <span style=\"text-decoration: underline;\">neu<\/span>roprosthesis<\/strong><\/span><\/h4>\n<p>After stroke, muscles retain their ability to generate force, but the neuromuscular pathways that control brain-to-muscle communication are disrupted, causing many people with stroke to be unable to effectively access these pathways and control their muscles. To make use of residual muscle capacity and improve effective muscle control, we are developing a multi-channel functional electrical stimulation (FES) neuroprosthesis that can activate affected muscles and improve walking ability. The neuroprosthesis combines low-energy electrical pulses with sensor technology and adaptive gait algorithms to provide individualized lower extremity assistance during walking after stroke. Preliminary work has shown meaningful improvements in walking speed and paretic limb propulsion after a single session of use.\u00a0The underlying vision of the reNeu is to renew walking ability by capitalizing on the synergy between functional electrical stimulation and soft robotic exosuits. Both of these wearable technologies can help people with post-stroke hemiparesis and other neuromotor impairments walk faster and with improved gait quality, but their mechanisms of action and, in turn, their rehabilitative effects, differ. Whereas soft robotic exosuits use mechanical cable-driven assistance, FES neuroprostheses use electrical stimulation to activate a person\u2019s own muscles.\u00a0 The reNeu project is currently focused on development and clinical validation of the neuroprosthesis, before progressing towards a combined reNeu system with FES and exosuit assistance working in tandem to provide smarter, more individualized gait assistance and rehabilitation.<\/p>\n<p><img loading=\"lazy\" src=\"\/nrl\/files\/2020\/10\/reNeu-platform.png\" alt=\"\" class=\"alignnone wp-image-1637\" width=\"1221\" height=\"601\" srcset=\"https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform.png 6825w, https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform-636x313.png 636w, https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform-1024x504.png 1024w, https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform-768x378.png 768w, https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform-1536x756.png 1536w, https:\/\/sites.bu.edu\/nrl\/files\/2020\/10\/reNeu-platform-2048x1008.png 2048w\" sizes=\"(max-width: 1221px) 100vw, 1221px\" \/><\/p>\n<h4><span style=\"color: #993300;\"><u>Project Leads<\/u><\/span><\/h4>\n\t<div class=\"profile-listing\">\n\t\t<ul class=\"default\">\n\t\t\t\t\t\t\t\t<li class=\"has-title\">\n\t\t\t\t<a href=\"https:\/\/sites.bu.edu\/nrl\/profile\/ashlyn-aiello\/\">\n\t\t\t\t<span class=\"profile-name\">Ashlyn Aiello<\/span>\n\t\t\t\t<\/a>\n\t\t\t\t<span class=\"profile-title\">PhD Student<\/span>\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"has-title\">\n\t\t\t\t<a href=\"https:\/\/sites.bu.edu\/nrl\/profile\/dabin-choe\/\">\n\t\t\t\t<span class=\"profile-name\">Dabin Choe<\/span>\n\t\t\t\t<\/a>\n\t\t\t\t<span class=\"profile-title\">Visiting Scientist<\/span>\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t<\/div>\n\n<h4><span style=\"color: #993300;\"><u>Team<\/u><\/span><\/h4>\n\t<div class=\"profile-listing\">\n\t\t<ul class=\"default\">\n\t\t\t\t\t\t\t\t<li class=\"has-title\">\n\t\t\t\t<a href=\"https:\/\/sites.bu.edu\/nrl\/profile\/lynn-deming\/\">\n\t\t\t\t<span class=\"profile-name\">Lynn Deming<\/span>\n\t\t\t\t<\/a>\n\t\t\t\t<span class=\"profile-title\">Research Physical Therapist<\/span>\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"has-title\">\n\t\t\t\t<a href=\"https:\/\/sites.bu.edu\/nrl\/profile\/lillian-ribeirinha-braga\/\">\n\t\t\t\t<span class=\"profile-name\">Lillian Ribeirinha-Braga<\/span>\n\t\t\t\t<\/a>\n\t\t\t\t<span class=\"profile-title\">Research Coordinator<\/span>\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"has-title\">\n\t\t\t\t<a href=\"https:\/\/sites.bu.edu\/nrl\/profile\/johanna-spangler\/\">\n\t\t\t\t<span class=\"profile-name\">Johanna Spangler, PT, DPT<\/span>\n\t\t\t\t<\/a>\n\t\t\t\t<span class=\"profile-title\">Clinical Research Project Manager<br \/>\r\nResearch Physical Therapist<\/span>\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t<\/div>\n\n<h4><span style=\"color: #993300;\"><u>Publications<\/u><\/span><\/h4>\n<p><span><strong><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\">Towards Precision Rehabilitation of Post-Stroke Speed and Propulsion Using a Wearable Functional Electrical Stimulation Platform.<br \/>\n<\/span><\/span><span color=\"#2a2a2a\"><em>Combined Sections Meeting of the American Physical Therapy Association<\/em><\/span><span color=\"#2a2a2a\"><em>. <\/em><\/span><\/span><\/strong><\/span><br \/>\n<span size=\"2\"><span color=\"#2a2a2a\">(submitted)<\/span><\/span><\/p>\n<p><span><strong><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\">Overground Gait Training with a Plantarflexor Neuroprosthesis Increases Walking Speed and Paretic Propulsion after Stroke. <br style=\"clear: both;\" \/><\/span><\/span><\/span><\/strong><\/span><span><strong><span size=\"2\"><span style=\"color: #000000;\"><span color=\"#2a2a2a\"><em>Combined Sections Meeting of the American Physical Therapy Association<\/em><em>.\u00a0<\/em><\/span><\/span><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><em><br \/>\n<\/em><\/span><\/span><\/span><\/strong><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><em><\/em><\/span><\/span><\/span><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><span style=\"color: #000000;\">(see<\/span> <a href=\"\/nrl\/files\/2022\/08\/CSM2022_FES_Poster_v5.pdf\">pdf<\/a><span style=\"color: #000000;\">)<\/span><\/span><\/span><\/span><\/span><\/p>\n<p><span><strong><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\">These Legs were Made for Propulsion: Advancing the Diagnosis and Treatment of Post-Stroke Propulsion Deficits.<br \/>\n<\/span><\/span><span color=\"#2a2a2a\"><em>Journal of NeuroEngineering and Rehabilitation<\/em><\/span><span color=\"#2a2a2a\"><em>. <\/em><\/span><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><em><br \/>\n<\/em><\/span><\/span><\/span><\/strong><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><em><\/em><\/span><\/span><\/span><span size=\"2\"><span style=\"color: #000080;\"><span color=\"#2a2a2a\"><span style=\"color: #000000;\">(see<\/span> <a href=\"\/nrl\/files\/2021\/01\/s12984-020-00747-6.pdf\">pdf<\/a> <span style=\"color: #000000;\">or<\/span> <a href=\"https:\/\/jneuroengrehab.biomedcentral.com\/articles\/10.1186\/s12984-020-00747-6\">link<\/a><span style=\"color: #000000;\">)<\/span><\/span><\/span><\/span><\/span><\/p>\n<p><span><strong><span size=\"2\"><span style=\"color: #000080;\">A Soft Robotic Exosuit Improves Walking in Patients after Stroke.<\/span><br \/>\n<\/span><\/strong><\/span><span><span color=\"#2a2a2a\"><em><strong><span size=\"2\">Science Translational Medicine.<br \/>\n<\/span><\/strong><\/em><\/span><\/span><span><span color=\"#2a2a2a\"><span size=\"2\">(see <a href=\"https:\/\/sites.bu.edu\/nrl\/files\/2017\/07\/eaai9084.full_.pdf\">pdf<\/a> or <a href=\"http:\/\/stm.sciencemag.org\/content\/9\/400\/eaai9084\">link<\/a>)<\/span><\/span><\/span><\/p>\n<p><span><span color=\"#2a2a2a\"><\/span><\/span><span><span size=\"2\" style=\"color: #000080;\"><strong>Identifying Candidates for Targeted Gait Rehabilitation after Stroke: Better Prediction Through Biomechanics-Informed Characterization<\/strong><\/span><span size=\"2\"><strong><span style=\"color: #000080;\">.<\/span><\/strong><br \/>\n<\/span><\/span><span><span color=\"#2a2a2a\" size=\"2\"><em><strong>Journal of NeuroEngineering and Rehabilitation.<br \/>\n<\/strong><\/em><\/span><\/span><span><span color=\"#2a2a2a\" size=\"2\"><span size=\"2\">(see <a href=\"http:\/\/em.rdcu.be\/wf\/click?upn=KP7O1RED-2BlD0F9LDqGVeSGEIcVSZqO0dyvcMHgzV3t0-3D_L1k9cni81MLLN5f9kjYMT-2BFPap1B-2F4fxoSkzOCn4eG36OctmT5B9TyaGlUiZ80IhXXIxmIKUrKVg9-2Bu4aHIdzK2f9tVbMLZ4fFOwq5cNd6oFgrcIN-2B5Qz1sYsF6w891iWC9tdaC3rDIoecwJb0DfCjwGvTQ5eKp-2BjknkIByCrAWuQt-2FY2LASqRju0-2FAZthVtSoNzCtzp0sQFL0w3V14Gzw-3D-3D\" target=\"_blank\" rel=\"noopener noreferrer\">pdf<\/a> or <a href=\"http:\/\/jneuroengrehab.biomedcentral.com\/articles\/10.1186\/s12984-016-0188-8\">link<\/a>)<\/span><a href=\"http:\/\/louisawad.com\/uploads\/3\/4\/4\/2\/34422585\/nnr-2014-awad_prop_and_tla_are_key_determinants_of_poststroke_walking.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><span size=\"2\"><\/span><\/a><strong><a href=\"http:\/\/louisawad.com\/uploads\/3\/4\/4\/2\/34422585\/nnr-2014-awad_prop_and_tla_are_key_determinants_of_poststroke_walking.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><span size=\"2\"><br \/>\n<\/span><\/a><\/strong><\/span><\/span><strong><span><span size=\"2\"><\/span><\/span><\/strong><\/p>\n<p><span style=\"color: #000080;\"><strong><span size=\"2\">Reducing the Cost of Transport and Increasing Walking Distance After Stroke: a Randomized Controlled Trial on Fast Training Combined with Functional Electrical Stimulation<\/span><\/strong><span size=\"2\"><span color=\"#2a2a2a\"><\/span><\/span><strong>.<\/strong><\/span><br \/>\n<span><span size=\"2\"><em><strong>Neurorehabilitation and Neural Repair.<br \/>\n<\/strong><\/em><strong><\/strong><\/span><\/span><span><span size=\"2\"><span color=\"#2a2a2a\">(see\u00a0<a href=\"\/nrl\/files\/2016\/10\/Neurorehabil-Neural-Repair-2016-Awad-661-70.pdf\">pdf<\/a> or <a href=\"http:\/\/nnr.sagepub.com\/content\/30\/7\/661.full\">link<\/a>)<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000080;\"><strong><span size=\"2\">Targeting Paretic Propulsion to Improve Poststroke Walking Function: a Preliminary Study<\/span><\/strong><span size=\"2\"><span color=\"#2a2a2a\"><\/span><\/span><strong>.<\/strong><\/span><br \/>\n<span><span color=\"#2a2a2a\" size=\"2\"><em><strong>Archives of Physical Medicine and\u00a0Rehabilitation.<br \/>\n<\/strong><\/em><\/span><\/span><span><span color=\"#2a2a2a\" size=\"2\"><span size=\"2\"><span color=\"#2a2a2a\">(see\u00a0<a href=\"\/nrl\/files\/2016\/10\/Archives_Targeting-Paretic-Propulsion.pdf\">pdf<\/a> or <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0003999313013105\">link<\/a>)<\/span><\/span><strong><\/strong><em><strong><\/strong><\/em><\/span><\/span><\/p>\n<h4><span style=\"color: #993300;\"><u>Study Flyer<\/u><\/span><\/h4>\n<p><a href=\"\/nrl\/files\/2022\/08\/Recruitment-Flyer-v2.pdf\"><\/a><a href=\"\/nrl\/files\/2022\/08\/Recruitment-Flyer-v2.pdf\">We are recruiting research participants to walk with ankle electrical stimulation!<\/a><a href=\"\/nrl\/files\/2022\/08\/Recruitment-Flyer-v2.pdf\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>reNeu: A soft, hybrid robotic exosuit neuroprosthesis After stroke, muscles retain their ability to generate force, but the neuromuscular pathways that control brain-to-muscle communication are disrupted, causing many people with stroke to be unable to effectively access these pathways and control their muscles. To make use of residual muscle capacity and improve effective muscle control, [&hellip;]<\/p>\n","protected":false},"author":12262,"featured_media":0,"parent":960,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/pages\/1639"}],"collection":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/users\/12262"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/comments?post=1639"}],"version-history":[{"count":15,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/pages\/1639\/revisions"}],"predecessor-version":[{"id":2511,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/pages\/1639\/revisions\/2511"}],"up":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/pages\/960"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/nrl\/wp-json\/wp\/v2\/media?parent=1639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}