{"id":333,"date":"2017-11-14T16:53:26","date_gmt":"2017-11-14T21:53:26","guid":{"rendered":"https:\/\/sites.bu.edu\/morgan-lab\/?page_id=333"},"modified":"2021-06-09T13:14:23","modified_gmt":"2021-06-09T17:14:23","slug":"vascular-dementia","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/morgan-lab\/topics-of-interest\/vascular-dementia\/","title":{"rendered":"Vascular Dementia"},"content":{"rendered":"<div class=\"\">\n<p class=\"\">Vascular dementia occurs from impaired blood flow to the brain and affects thought processes such as judgement, planning, and memory. It\u00a0can be the result of a stroke blocking an artery in the brain, or as our research is testing, may be attributed to decreased vascular function\u00a0due to aging-induced aortic stiffening which may cause microbleeds in the brain.<\/p>\n<\/div>\n<figure id=\"attachment346\" aria-describedby=\"caption-attachment346\" style=\"width: 646px\" class=\"wp-caption aligncenter\"><a href=\"\/morgan-lab\/files\/2017\/11\/BrainSlice.jpg\"><img loading=\"lazy\" src=\"\/morgan-lab\/files\/2017\/11\/BrainSlice-636x477.jpg\" alt=\"BrainSlice\" width=\"636\" height=\"477\" class=\"wp-image-346 size-medium\" srcset=\"https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/BrainSlice-636x477.jpg 636w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/BrainSlice-1024x768.jpg 1024w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/BrainSlice-768x576.jpg 768w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/BrainSlice-1536x1152.jpg 1536w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/BrainSlice-2048x1536.jpg 2048w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/a><figcaption id=\"caption-attachment346\" class=\"wp-caption-text\">Extravascular bleeds stained with Prussian Blue<\/figcaption><\/figure>\n<div class=\"\">\n<p class=\"\">Vascular health is critical for neural function. Damage to the vascular system, particularly in the small vessels in\u00a0the brain, hinders the brains ability to function properly.<\/p>\n<\/div>\n<div class=\"\">\n<p class=\"\">Our current research focuses on the aorta, which functions as a shock absorber and prevents\u00a0the full force of the heartbeat from reaching\u00a0delicate\u00a0blood vessels in the brain. Studies show that the aorta stiffens with age, which limits its ability to protect\u00a0vessels in the brain from damage. Consequent microbleeds impair brain function and can ultimately lead to dementia.<\/p>\n<\/div>\n<div class=\"\">\n<p class=\"\">Vascular dementia involves very similar symptoms to those attributed to Alzheimer&#8217;s Disease. Our current research\u00a0tests the idea that vascular damage in the brain may precede and even lead to Alzheimer&#8217;s Disease.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vascular dementia occurs from impaired blood flow to the brain and affects thought processes such as judgement, planning, and memory. It\u00a0can be the result of a stroke blocking an artery in the brain, or as our research is testing, may be attributed to decreased vascular function\u00a0due to aging-induced aortic stiffening which may cause microbleeds in [&hellip;]<\/p>\n","protected":false},"author":13989,"featured_media":0,"parent":602,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/333"}],"collection":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/users\/13989"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/comments?post=333"}],"version-history":[{"count":9,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/333\/revisions"}],"predecessor-version":[{"id":670,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/333\/revisions\/670"}],"up":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/602"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/media?parent=333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}