{"id":327,"date":"2017-11-07T17:14:09","date_gmt":"2017-11-07T22:14:09","guid":{"rendered":"https:\/\/sites.bu.edu\/morgan-lab\/?page_id=327"},"modified":"2021-06-09T13:14:23","modified_gmt":"2021-06-09T17:14:23","slug":"aortic-stiffness","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/morgan-lab\/topics-of-interest\/aortic-stiffness\/","title":{"rendered":"Aortic Stiffness"},"content":{"rendered":"<p><span>Shock absorption via Src-mediated focal adhesion\/nonmuscle cytoskeleton regulation is defective in old aortas: model of how changes in stiffness generated by cross-bridge attachment and remodeling of focal adhesions and nonmuscle cortical cytoskeleton can be regulated by a PP2-sensitive mechanism present in young but not old aortas.<\/span><\/p>\n<p><a href=\"\/morgan-lab\/files\/2017\/11\/F8.large_.jpg\"><img loading=\"lazy\" src=\"\/morgan-lab\/files\/2017\/11\/F8.large_-636x573.jpg\" alt=\"F8.large\" width=\"636\" height=\"573\" class=\"size-medium wp-image-328 aligncenter\" srcset=\"https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/F8.large_-636x573.jpg 636w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/F8.large_-768x692.jpg 768w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/F8.large_-1024x923.jpg 1024w, https:\/\/sites.bu.edu\/morgan-lab\/files\/2017\/11\/F8.large_.jpg 1800w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/a><\/p>\n<p>Read the full article: <a href=\"http:\/\/ajpheart.physiology.org\/content\/307\/8\/h1252\">\u00a0Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Shock absorption via Src-mediated focal adhesion\/nonmuscle cytoskeleton regulation is defective in old aortas: model of how changes in stiffness generated by cross-bridge attachment and remodeling of focal adhesions and nonmuscle cortical cytoskeleton can be regulated by a PP2-sensitive mechanism present in young but not old aortas. Read the full article: \u00a0Aging impairs smooth muscle-mediated regulation [&hellip;]<\/p>\n","protected":false},"author":13989,"featured_media":0,"parent":602,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/327"}],"collection":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/users\/13989"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/comments?post=327"}],"version-history":[{"count":1,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/327\/revisions"}],"predecessor-version":[{"id":329,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/327\/revisions\/329"}],"up":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/pages\/602"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/morgan-lab\/wp-json\/wp\/v2\/media?parent=327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}