{"id":34,"date":"2022-06-05T11:39:10","date_gmt":"2022-06-05T15:39:10","guid":{"rendered":"https:\/\/sites.bu.edu\/mckeown\/?page_id=34"},"modified":"2023-01-23T17:46:29","modified_gmt":"2023-01-23T22:46:29","slug":"student-opportunities","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/mckeown\/student-opportunities\/","title":{"rendered":"Research"},"content":{"rendered":"<h4><img loading=\"lazy\" src=\"\/mckeown\/files\/2023\/01\/wordcloud-3-e1674238132539-636x415.png\" alt=\"\" width=\"533\" height=\"348\" class=\"aligncenter wp-image-289 \" srcset=\"https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/wordcloud-3-e1674238132539-636x415.png 636w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/wordcloud-3-e1674238132539-768x501.png 768w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/wordcloud-3-e1674238132539.png 1024w\" sizes=\"(max-width: 533px) 100vw, 533px\" \/><\/h4>\n<hr \/>\n<h3 style=\"text-align: center;\">Nutrigenetics &amp; Genomics of Sugar-Sweetened Beverage Induced Metabolic Disease<\/h3>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" src=\"\/mckeown\/files\/2023\/01\/SSB-636x424.jpg\" alt=\"\" width=\"538\" height=\"359\" class=\"wp-image-274 aligncenter\" srcset=\"https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/SSB-636x424.jpg 636w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/SSB-1024x683.jpg 1024w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/SSB-768x512.jpg 768w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/SSB.jpg 1200w\" sizes=\"(max-width: 538px) 100vw, 538px\" \/><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Excess sugar-sweetened beverage (SSB) consumption is linked to disorders associated with lipid accumulation including non-alcoholic fatty liver disease and insulin resistance. ChREBP is a key transcriptional regulator of glucose and lipid metabolism, and evidence links sugar-induced hepatic ChREBP activity to circulating FGF21 levels and cardiovascular risk. The proposed study will examine underlying mechanisms by which sugar consumption and genetic variants contribute to the increased prevalence of cardiometabolic disease.<\/span><\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<h3 style=\"text-align: center;\">Diet-Related Fibers &amp; Human Health Outcomes Database<\/h3>\n<p><img loading=\"lazy\" src=\"\/mckeown\/files\/2023\/01\/dietary-fibers-1-636x424.jpg\" alt=\"\" width=\"571\" height=\"381\" class=\"wp-image-273 aligncenter\" srcset=\"https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/dietary-fibers-1-636x424.jpg 636w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/dietary-fibers-1-1024x683.jpg 1024w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/dietary-fibers-1-768x512.jpg 768w, https:\/\/sites.bu.edu\/mckeown\/files\/2023\/01\/dietary-fibers-1.jpg 1368w\" sizes=\"(max-width: 571px) 100vw, 571px\" \/><\/p>\n<p><b>Brief Overview<\/b><\/p>\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/iafns.org\/our-work\/research-tools-open-data\/dietary-fiber-database\/\">The Diet-Related Fibers and Human Health Outcomes Database<\/a> is a resource to assist health researchers and policy-makers in evaluating evidence linking fibers to specific physiological health outcomes in a quick and efficient manner. This project is funded by the Institute for the Advancement of Food and Nutrition Sciences (IAFNS) a non-profit organization that catalyzes science for the benefit of public health.\u00a0 \u00a0\u00a0<\/span><\/p>\n<p><strong>Presentations<\/strong><\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=l2xwOv7pRCM\">A Comprehensive Database Linking Dietary Fibers and Health Rationale and Methods<\/a><strong> <\/strong><\/p>\n<p><a href=\"https:\/\/iafns.org\/event\/11th-vahouny-fiber-symposium\/\">11th Vahouny Fiber Symposium<\/a><\/p>\n<p><a href=\"https:\/\/youtu.be\/Gm8FOI1_G6Q\">12<sup>th<\/sup> Vahouny Fiber Symposium<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nutrigenetics &amp; Genomics of Sugar-Sweetened Beverage Induced Metabolic Disease Excess sugar-sweetened beverage (SSB) consumption is linked to disorders associated with lipid accumulation including non-alcoholic fatty liver disease and insulin resistance. ChREBP is a key transcriptional regulator of glucose and lipid metabolism, and evidence links sugar-induced hepatic ChREBP activity to circulating FGF21 levels and cardiovascular risk. [&hellip;]<\/p>\n","protected":false},"author":19233,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/pages\/34"}],"collection":[{"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/users\/19233"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/comments?post=34"}],"version-history":[{"count":15,"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/pages\/34\/revisions"}],"predecessor-version":[{"id":311,"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/pages\/34\/revisions\/311"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/mckeown\/wp-json\/wp\/v2\/media?parent=34"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}