Principal Investigator

Ryan W. Logan, Ph.D.
Associate Professor

Boston University School of Medicine
Department of Pharmacology and Experimental Therapeutics
Center for Systems Neuroscience
Graduate Program in Neuroscience
Program in Bioinformatics

Education and Training:
2004 – BA, University of Maine
2009 – PhD, University of Maine
2009-2011 – Postdoc, Rutgers University
2011-2012 – Postdoc, The Jackson Laboratory
2012-2015 – Postdoc, University of Pittsburgh School of Medicine
2015-2020 – Assistant Professor, University of Pittsburgh School of Medicine


Principal Investigator

Stephanie Puig, M.S., Ph.D.
Assistant Professor

Stef is a Research Assistant Professor in the Logan lab. She received her Master’s degree in Physiology and Neuroscience from the University of Pierre et Marie Curie in Paris, and her Ph.D. in Neuropharmacology and Neurobiology of Addiction from the University of Paris Descartes. During her postdoctoral training in the Pittsburgh Center for Pain Research at the University of Pittsburgh, she studied the involvement of receptor tyrosine kinases in the mechanisms of opioid analgesic tolerance and opioid withdrawal. She now works in collaboration with Dr. Ryan Logan on projects involving molecular mechanisms and neural circuitry of opioid analgesic tolerance during the treatment of chronic pain. She is also interested in the mechanics that cause physical dependence and addiction to prescription opioids. Her goal is to develop her independent research program that will focus on finding safer strategies to treat chronic pain, preserve long term opioid analgesia and decrease the risks of addiction. Outside of the lab, she likes to dance, hike, bike, read novels, and craft with her kids!

Postdoctoral Fellows

Madelyn H. Ray, Ph.D.
T32 Postdoctoral Fellow

Maddie is a postdoctoral fellow in the Logan Lab. Maddie received her Ph.D. in Neuroscience in 2021 from Boston College. At Boston College, Maddie worked in Dr. Michael McDannald’s behavioral neuroscience lab where she used a variety of techniques including in vivo electrophysiology and optogenetics to examine the nucleus accumbens core and its involvement in adaptive scaling of fear to various threat probabilities. She earned her B.S. in Psychological Sciences in 2016 from Kansas State University where she worked in Dr. Charles Pickens’ behavioral neuroscience lab. At Kansas State University, Maddie studied the effects of voluntary ethanol consumption and orbitofrontal cortex lesions on flexible decision making. Outside of the lab, Maddie enjoys running, candle-making, board games, and being a pet mom to her two cats, Emmy and Basal Ganglia. You can learn more about Maddie by checking out her twitter and website

Luca Posa, Pharm.D., Ph.D.
Postdoctoral Fellow

Luca is a postdoctoral fellow in the Logan Lab. He received his B.Sc. in Biology and
later his Pharm.D. both form the University of Bologna. During his Pharm.D., he studied the rationale of the opioid treatment rotation at the University of Paris Descartes. Then, he pursued his Ph.D. in Psychiatry at McGill University, where he used cutting-edge techniques to study the interaction between the melatonergic and opioid systems in the antinociceptive pathway and reward. He received the Fonds de Recherche- Santé du Québec Fellowship and the Edwards Studentship in Pain Research. Luca moved to the University of Maryland as postdoctoral fellow to study the role of monoamines in chronic pain condition, and later joined the Logan lab at BU where is investigating the neural circuitry and cellular determinants of opioid analgesic tolerance. He is also interested in studying the role of the circadian rhythm disruption in reward/addiction. Outside of the lab, Luca enjoys discovering new spots in Boston, biking, hiking, concerts and cooking. You can learn more about Luca by checking out his twitter and scholar website.

Graduate Students

Mackenzie Gamble
PhD Student in Molecular and Translational Medicine

Mackenzie is a second year Ph.D. student in the program of Molecular and Translational Medicine in the Logan lab. He earned my B.S. in Neuroscience in 2016 from Stonehill College where he worked in the sleep labs at the VA Boston Healthcare System. His background spans both neuroanatomy and behavioral neuroscience both in the context of preclinical sleep research. This work had two objectives 1) dissecting the neural circuitry of arousal and 2) modeling insomnia in rodents to evaluate novel hypnotics, how they differentially affect the sleep-wake cycle, and in turn impact memory. Outside of the lab Mackenzie enjoys macrophotography, running in the Arnold Arboretum, and cooking.

Research Technicians

Ben Williams
Research Technician & Lab Manager

After growing up in Southern Maine, Ben studied Biochemistry and Microbiology at the University of Maine, and currently serves as the Research Technician and Lab Manager for the Logan Lab. His undergraduate thesis, which assessed the impact of diet on pro-inflammatory signaling and subsequent sleep quality, as well as his work as an EMT in central Maine where opioid use disorder is prevalent, inspired him to further explore the field of rhythms and substance use disorders. Ben plans to pursue a career in medicine where he aspires to bridge the gap between neuroscience benchwork and clinical patient care. Outside of the lab, Ben enjoys playing basketball, playing guitar, and sailing. You can learn more about Ben by checking out his twitter.

Sophia Miracle
Research Technician

Sophia graduated from Canisius College with a B.S in Animal Behavior, Ecology, and Conservation (ABEC), and Psychology in 2019, and has since been fully immersed in the field of Neuroscience. She has been a Research Technician since graduation in labs focusing on addiction in rodent models and is currently serving as a Research Technician in the Logan Lab. Her interests lie in exploring the neuronal processes behind psychological disorders, specifically anxiety and depression. Sophia’s goal is to pursue a Ph.D. in Neuroscience, further exploring the mechanisms of these disorders and their connection with addiction, and ultimately finding novel targets for treatments to help those who struggle with these disorders. When Sophia is not in the lab, you can find her playing video games, reading, and spending time with her cats. To learn more you can visit Sophia’s LinkedIn at

Undergraduate Students

Ashley McDonald

Undergraduate Summer Intern

Ashley is a rising senior at Middlebury College studying Neuroscience as well as taking the premed pathway. She has found a specific interest in her undergraduate work investigating how addictive drugs alter the brain and therefore behavior. Recently, she has written a research proposal for investigating the effects of opioids on hippocampal gamma oscillations in the brain and how these alterations lead to memory impairment. Last summer, she worked as an EMT at the fire department in her local town of New Fairfield, CT. For the future, she hopes to continue studying neuroscience at medical school. Outside of the lab, Ashley plays ice hockey at Middlebury College and she also enjoys snowboarding, wakeboarding and mountain biking.

Phoebe Wang

Undergraduate Research Assistant

Phoebe is a rising senior at Boston University studying Neuroscience as well as taking the premedical pathway. She has an interest in investigating the relationship between drugs and behavior and how this relationship can affect disorders such as anxiety and depression. Recently, she has written a research proposal on examining the neuromotor effects of disabling dopaminergic neurons in the fly brain. For the future, she hopes to continue studying Neuroscience at medical school and furthering her knowledge on psychiatric disorders. Outside of the lab, she enjoys discovering new eats in Boston, cooking, violin, and volunteering. 


Past Members

Navsharan Singh – 2021-2022 – Master’s Student

Mariam AlAdsani – 2021-2022 – Undergraduate Researcher

Julia Michaud – 2021 – Undergraduate Researcher

Sam-Moon Kim – 2016-2020 – Postdoctoral Fellow
Micah Shelton – 2016-2020 – Project Manager
Kelly Barko – 2018-2020 – Research Associate
Jeffrey Oliver-Smith – 2015-2017 – Research Associate

Rotation Graduate Students

Maddie Kuppe, 2022 – Neuro Student

Roxanne Siuda, 2021 – Pharm Student
Kerry Breen, 2021 – Pharm Student
Xavier Cambri, 2021 – Pharm Student
Yuehan (Vicki) Li, 2021 – Pharm Student
Benjamin Snyder, 2021 – MD/PhD Student