{"id":24,"date":"2014-02-24T14:40:59","date_gmt":"2014-02-24T19:40:59","guid":{"rendered":"https:\/\/sites.bu.edu\/liugroup\/?page_id=24"},"modified":"2014-02-24T14:40:59","modified_gmt":"2014-02-24T19:40:59","slug":"developing-conditional-knockout-tools","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/liugroup\/research\/developing-chemical-genetic-tools-for-epigenetic-studies\/developing-conditional-knockout-tools\/","title":{"rendered":"Developing conditional knockout tools."},"content":{"rendered":"<div>\n<p>To address this necessity in epigenetic studies, we are developing conditional knockout tools at both the protein and RNA (e.g., targeting non-coding RNAs) levels and such a tool will be applicable to studies in animal models.\u00a0 Once developed, they will be applied in two major applications:<\/p>\n<p>1)\u00a0\u00a0\u00a0\u00a0\u00a0 Study host-pathogen interactions in animal model directly and guide the development of anti-microbial drugs and vaccines;<\/p>\n<p>2)\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0As the tool to study processes related to development and ageing in animal models with special emphasis on chemical basis of biological clocks.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>To address this necessity in epigenetic studies, we are developing conditional knockout tools at both the protein and RNA (e.g., targeting non-coding RNAs) levels and such a tool will be applicable to studies in animal models.\u00a0 Once developed, they will be applied in two major applications: 1)\u00a0\u00a0\u00a0\u00a0\u00a0 Study host-pathogen interactions in animal model directly and [&hellip;]<\/p>\n","protected":false},"author":6817,"featured_media":0,"parent":20,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/pages\/24"}],"collection":[{"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/users\/6817"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/comments?post=24"}],"version-history":[{"count":1,"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/pages\/24\/revisions"}],"predecessor-version":[{"id":25,"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/pages\/24\/revisions\/25"}],"up":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/pages\/20"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/liugroup\/wp-json\/wp\/v2\/media?parent=24"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}