Research
OA Interventions
We are developing biomechanics and pain neuroscience informed interventions for people with knee osteoarthritis.
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Improving Quality and Quantity of Walking in Knee Osteoarthritis (IWALQQ-OA): The goal of this randomized controlled trial was to assess the feasibility of a mindful walking intervention in people with knee osteoarthritis (NCT03064139)
Telehealth Exercise and Mindfulness for Pain in Osteoarthritis (TEMPO): The goal of this randomized controlled trial is to assess the feasibility of a telehealth delivered mindful exercise intervention in people with knee osteoarthritis (NCT pending)
Radiofrequency ablation (RFA): Genicular nerve radiofrequency ablation for chronic knee pain due to knee OA and its effects on gait
PT and opioids after knee replacement: A real-world cohort study of association of Physical Therapy Interventions with Long-term Opioid Use after Total Knee Arthroplasty (Read more here)
PT and opioids in knee osteoarthritis: A real-world cohort study of association of timing of physical therapy interventions after knee osteoarthritis diagnosis and opioid use
OA Biomechanics AI and Technologies
We are developing technologies to assess movement patterns in everyday life of people with knee osteoarthritis.
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Deep learning using wearable-sensor data: Estimation of knee joint kinematics and kinetics from wearable sensors using deep learning
Wearable Sensors in Knee Osteoarthritis: The goal of this clinical trial is to develop wearable sensor technologies for assessment of gait and chair stand function in people with knee osteoarthritis (NCT04243096)
At-home assessment of movement using wearable sensors: Reliability of wearable sensors for assessing gait and chair stand function at home in people with knee osteoarthritis
Assessment of varus thrust using wearable sensors: Quantifying varus thrust in knee osteoarthritis using wearable inertial sensors: A proof of concept
OA Mechanisms
We are examining mechanisms related to disease worsening in people with knee osteoarthritis.
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Neuroimaging of pain and movement: Using functional near-infrared spectroscopy (fNIRS) to study brain function during movement and exercise in people with central pain sensitization due to knee osteoarthritis.
Machine learning using ground reaction force and physical activity data: Association of ground reaction forces during walking and physical activity with cartilage loss over 2-years in people with knee osteoarthritis: a machine learning analysis in the Multicenter Osteoarthritis Study (MOST)
Machine learning using wearable-sensor gait data: Association of wearable-sensor derived gait measures and knee pain: a machine learning analysis in the Multicenter Osteoarthritis Study (MOST)
Association of pain sensitization with gait and physical activity: Studies on association of measures of quantitative sensory testing and measures of gait and physical activity in the large Multicenter Osteoarthritis Study (MOST)