New publication in Osteoarthritis and Cartilage

New publication from our group in Osteoarthritis and Cartilage Journal on “Associations of Pain Sensitivity and Conditioned Pain Modulation with Physical Activity: Findings from the Multicenter Osteoarthritis Study (MOST)”

Soyoung Lee is the first author.

Using data from the Multicenter Osteoarthritis Study (MOST)(n=1,873), we observed that greater peripheral and/or central pain sensitivity was related to lower wearable accelerometer-derived daily step counts. However, conditioned pain modulation was not related to physical activity measures.

While this cross-sectional study does not inform causality or directionality, strategies to mitigate pain sensitization may be a necessary early step to increase physical activity in people with chronic pain due to knee osteoarthritis. Or increasing physical activity may partially improve pain via its action on pain sensitization.