{"id":5,"date":"2021-06-23T14:48:12","date_gmt":"2021-06-23T18:48:12","guid":{"rendered":"https:\/\/sites.bu.edu\/junlab\/jun-lab\/"},"modified":"2021-10-20T16:47:43","modified_gmt":"2021-10-20T20:47:43","slug":"jun-lab","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/junlab\/","title":{"rendered":"Welcome to Jun Lab"},"content":{"rendered":"<h2>Integrated Genomics and Precision Medicine for Alzheimer Disease<\/h2>\n<p><span style=\"font-weight: 400;\">Dr. Gyungah Jun is a globally renowned Alzheimer\u2019s disease (AD) geneticist and an expert in analysis of \u201cbig data\u201d. She has been a key member of the Alzheimer\u2019s Disease Genetics Consortium (ADGC) and the International Genomics of Alzheimer\u2019s Project (IGAP) to identify AD risk genes within APOE genotype subgroups. She has led and conducted innovative analysis approaches to identify distinct genetic signatures contributing to Alzheimer\u2019s disease risk in APOE4-positive vs. APOE4-negative subgroups. She is working on development of a novel therapeutic concept to mimic the protective mechanism of the APOE \u03b52 allele. She has unique industry experience, served as the Director and Head of Neurogenetics and Integrated Genomics in Alzheimer\u2019s disease therapeutics. Translational research for AD therapeutics remains her main focus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Under Dr. Jun\u2019s direction, the lab is actively involved in large coordinated national initiatives for AD therapeutics empowered by artificial intelligence (AI) and machine learning (ML) that utilizes high-throughput human genome data. The lab also leads efforts on genome guided drug discovery for AD including innovative drug discovery, drug repurposing, and platform development for open collaboration with academia and industry. Active research areas include Ultrascale Machine Learning to Empower Discovery in Alzheimer\u2019s Disease Biobanks (AI4AD), Asian Cohort for Alzheimer\u2019s Disease (ACAD), APOE in the Predisposition to (APOE-Biomarker), Protection from and Prevention of Alzheimer\u2019s Disease, Genomic and Biological Studies of APOE e2 in Alzheimer Disease (APOE2), and Precision Monitoring and Assessment in the Framingham Study: Cognitive, MRI, Genetic and Biomarker Precursors of AD &amp; Dementia (FHS-BAP).<\/span><\/p>\n<p><strong>Address:<\/strong><br \/>\n72 E Concord St, Boston, MA 02118<\/p>\n<p><strong>Phone:<\/strong><br \/>\n617-358-3581<\/p>\n<p><strong>Fax:<\/strong><br \/>\n617-358-3551<\/p>\n<p><iframe width=\"600\" height=\"450\" style=\"border: 0;\" src=\"https:\/\/www.google.com\/maps\/embed?pb=!1m18!1m12!1m3!1d1039.1255181203014!2d-71.0728832106364!3d42.3362529483352!2m3!1f0!2f0!3f0!3m2!1i1024!2i768!4f13.1!3m3!1m2!1s0x89e37a6aae4f9d07%3A0x3d11e2427c978cdf!2s72%20E%20Concord%20St%2C%20Boston%2C%20MA%2002118!5e0!3m2!1sen!2sus!4v1626230970513!5m2!1sen!2sus\" allowfullscreen=\"allowfullscreen\" loading=\"lazy\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Integrated Genomics and Precision Medicine for Alzheimer Disease Dr. Gyungah Jun is a globally renowned Alzheimer\u2019s disease (AD) geneticist and an expert in analysis of \u201cbig data\u201d. She has been a key member of the Alzheimer\u2019s Disease Genetics Consortium (ADGC) and the International Genomics of Alzheimer\u2019s Project (IGAP) to identify AD risk genes within APOE [&hellip;]<\/p>\n","protected":false},"author":19470,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/pages\/5"}],"collection":[{"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/users\/19470"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":12,"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":264,"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/pages\/5\/revisions\/264"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/junlab\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}