{"id":22,"date":"2013-01-15T16:01:03","date_gmt":"2013-01-15T21:01:03","guid":{"rendered":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/?page_id=22"},"modified":"2022-05-15T09:33:58","modified_gmt":"2022-05-15T13:33:58","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"<p><strong><span style=\"line-height: 110%; font-size: large;\">Selected Publications<\/span><\/strong><\/p>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Beermann, M.L., Homma, S., and Miller, J.B. (2022) Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: A pilot study. <em>BMC Research Notes<\/em> 15:163. <a href=\"https:\/\/doi.org\/10.1186\/s13104-022-06054-8\" target=\"_blank\" rel=\"noopener noreferrer\">online access<\/a> <\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\"> <span>Masteika, I. F., Sathya, A., Homma, S., Miller, B.M., Boyce, F.M., and Miller, J.B. (2022) Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, \u03b3H2AX accumulation, and Bax\/Bak-dependence. <em>Biology Open<\/em> vol. 11, bio059145 <a href=\"https:\/\/journals.biologists.com\/bio\/article\/11\/2\/bio059145\/274475\/Downstream-events-initiated-by-expression-of-FSHD\">online access<\/a><\/span><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\"> <span>Mitsuhashi, H., Homma, S., Beermann, M.L., Ishimaru, S., Takeda, H., Yu, B.K., Liu, K., Duraiswamy, S., Boyce, F.M., and Miller, J.B. (2019) Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers. <i>Scientific Reports\u00a0<\/i>9:2274 pp. 1-15<\/span>. <a href=\"https:\/\/www.nature.com\/articles\/s41598-018-36684-7\">online access<\/a>\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">\u00a0Mitsuhashi, H., Ishimaru, S., Homma, S., Yu, B., Honma, Y., Beermann, J.L., and Miller, J.B. (2018) Functional domains of the FSHD-associated DUX4 protein. <em>Biology Open<\/em> Apr 4. pii: bio.033977. doi: 10.1242\/bio.033977. <a href=\"http:\/\/bio.biologists.org\/content\/early\/2018\/04\/03\/bio.033977\">online access<\/a>\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Yoon, S., Beermann, M.L., Yu, B., Shao, D., Bachschmid, M., and Miller, J.B. (2018) Aberrant caspase activation in laminin-\u03b12-deficient human myogenic cells is mediated by p53 and sirtuin activity. <em>Journal of Neuromuscular Diseases<\/em>. 5:59-73. online publication Dec 20, 2017 doi: 10.3233\/JND-170262. PubMed PMID: 29278895. <a href=\"https:\/\/content.iospress.com\/articles\/journal-of-neuromuscular-diseases\/jnd170262\">online access<\/a><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Homma, S., Beermann, M.L., Yu, B., Boyce, F.M., and Miller, J.B. (2016) Nuclear bodies reorganize during myogenesis and are differentially disrupted by expression of FSHD-associated DUX4. <em>Skeletal Muscle\u00a0<\/em>vol. 6, paper 42, pp 1-16. \u00a0<a href=\"http:\/\/rdcu.be\/ncl0\" target=\"_blank\" rel=\"noopener noreferrer\">online access<\/a><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Jones. T.I., King, O.D., Himeda, C.L., Homma, S., Chen, J.C.J., Beermann, M.L., Yan, C., Emerson, C.P., Miller, J.B., Wagner, K.R., Jones, P.L. (2015) Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy. <em>Clinical Epigenetics\u00a0<\/em>Vol. 7, paper 37, pp 1-22<em>.\u00a0<\/em><a href=\"http:\/\/www.clinicalepigeneticsjournal.com\/content\/7\/1\/37\">online access<\/a><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Homma, S., Beermann, M.L., Boyce, F., and Miller, J.B. (2015) Expression of FSHD-associated DUX4-FL alters proteostasis and induces TDP-43 aggregation. <i>Ann. Clin. Transl. Neurol. <\/i>2:151-166<i>\u00a0<\/i><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/acn3.158\/full\" target=\"_blank\" rel=\"noopener noreferrer\">online access<\/a>\u00a0<strong>This paper was profiled in\u00a0<em>FSH Watch\u00a0<\/em><\/strong><em><\/em>(Winter 2015, p.5)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Himeda, C., Debarnot, C., Homma, S., Beermann, M.L., Miller, J.B., Jones, P.L., and Jones, T.I. (2014) Myogenic enhancers regulate<i> <\/i>expression of the facioscapulohumeral muscular dystrophy associated <i>DUX4<\/i> gene. <i>Mol. Cell. Biol.<\/i>\u00a034:1942-1955\u00a0<strong> This paper was profiled in\u00a0<em>FSH Watch\u00a0<\/em><\/strong><em><\/em>(Spring 2014, p.15)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Yoon, S., Stadler, G., Beermann, M.L., Schmidt, E.V., Windelborn, J.A., Wright, W.E., and Miller, J.B. (2013) Immortalized myogenic cells from Congenital Muscular Dystrophy Type1A patients recapitulate aberrant caspase activation in pathogenesis: A new tool for MDC1A research. <i>Skeletal Muscle<\/i>\u00a03:28 (6 December 2013)(<a href=\"http:\/\/www.skeletalmusclejournal.com\/content\/3\/1\/28\/abstract\">Read the article)<\/a><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Jones, T.I., Chen, J.C.J., Rahimov, F., Homma, S., Arashiro, P., Beermann, M.L., King, O.D., Miller, J.B., Kunkel, L.M., Emerson, C.P., Wagner, K.R., and Jones, P.L. (2012) Facioscapulohumeral muscular dystrophy family studies of DUX4 expression: Evidence for disease modifiers and a quantitative model of pathogenesis. <em>Hum. Mol. Genet.<\/em> 21:4419-4430. (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22798623\">Abstract from PubMed<\/a>). <strong><a href=\"http:\/\/quest.mda.org\/news\/dux4-protein-not-unique-fshd-affected-muscles\">This paper was profiled in <i>MDA Quest<\/i> magazine.<\/a><\/strong><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Homma, S., Chen, J.C.J., Rahimov, F., Beermann, M.L., Hanger, K., Bibat, G.M., Wagner, K.R., Kunkel, L.M., Emerson, C.P., and Miller, J.B. (2012) A unique library of myogenic cells from facioscapulohumeral muscular dystrophy subjects and unaffected relatives: Family, disease, and cell function. <em>Eur. J. Hum. Genet.<\/em> 20:404-410 (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22108603\">Abstract from PubMed<\/a>)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Homma, S., Beermann, M.L., and Miller, J.B. (2011) Peripheral nerve pathology, including aberrant Schwann cell differentiation, is ameliorated by doxycycline in a laminin-alpha2-deficient mouse model of congenital muscular dystrophy. <em>Hum. Mol. Genet.<\/em> 20:2662-2672 (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21505075\">Abstract from PubMed<\/a>)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Beermann, M.L., Ardelt, M.A., Girgenrath, M., and Miller, J.B. (2010) Prdm1 (Blimp-1) and the expression of fast and slow myosin heavy chain isoforms during avian myogenesis. <em>PLoS One<\/em> <a href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0009951\">5(4): e9951.<\/a><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Vishnudas, V.K. and Miller, J. B. (2009) Interaction of Ku70 with Bax regulates pathogenesis in laminin-alpha2-deficient human muscle cell and mouse models of congenital muscular dystrophy. <em>Hum. Mol. Genet.<\/em> 18:4467-4477. (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2773263\/?tool=pubmed\">Full text from PubMed Central<\/a>)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Girgenrath, M., Beermann, M. L., Vishnudas, V. K., Homma, S., and Miller, J. B. (2008) Pathology is alleviated by doxycycline in a laminin-alpha2-deficient mouse model of congenital muscular dystrophy. <em>Ann. Neurol.<\/em> 65:47-56 (Published Online: Dec 11, 2008 DOI: 10.1002\/ana.21523) (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2639627\/?tool=pubmed\">Full text from PubMed Central<\/a>) <strong>*This paper was selected as a research highlight by Nature Reviews Neurology and was profiled in <em>MDA Quest<\/em> magazine.<\/strong><\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Girgenrath, M., Weng, S., Kostek, C. A., Browning, B., Wang, M., Brown, S.A., Winkles, J. A., Michaelson, J. S., Allaire, N; Schneider, P., Scott, M., Hsu, Y-M., Yagita, H., Flavell, R. A., Miller, J. B., Burkly, L. C., and Zheng, T. S. (2006) TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. <em>EMBO J.<\/em> 25:5826\u20135839.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miller, J. B. and Girgenrath, M. (2006) Role of apoptosis in neuromuscular diseases and potential usefulness of anti-apoptosis therapy. <em>Trends Mol. Med.<\/em> 12:279-286.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Dominov, J. A., Kravetz, A. J., Ardelt, M., Kostek, C. A., Beermann, M. L., Miller, J. B. (2005) Muscle-specific BCL2 expression ameliorates muscle disease in laminin-alpha2-deficient, but not dystrophin-deficient, mice. <em>Hum Mol Genet.<\/em> 14(8):1029-40.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Girgenrath, M., Kostek, C. A., and Miller, J. B. (2005) Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of resident stem cells. <em>BMC Neurol.<\/em> Vol. 5, paper 7 (pp1-10)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Girgenrath, M., Dominov, J. A., Kostek, C. A., Miller, J. B. (2004) Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy. <em>J Clin Invest.<\/em> 114(11):1635-1639. <strong>This paper was profiled in <em>MDA Quest<\/em> magazine<\/strong> (<a href=\"http:\/\/static.mda.org\/publications\/Quest\/q121resup.html\">vol. 12, no. 1. Jan. 2005<\/a>)<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Nowak, J. A., Malowitz, J., Girgenrath, M., Kostek, C. A., Kravetz, A. J., Dominov, J. A., Miller, J. B. (2004) Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax. <em>BMC Cell Biol.<\/em> 5(1):1-14.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Lykke-Andersen, K, Schaefer, L., Menon, S., Deng, X.-W., Miller, J. B. and Wei, N. (2003). Disruption of COP9 subunit Csn2 in mouse causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death. <em>Mol. Cell. Biol.<\/em> 23:6790-6797.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Pavlath, G. K., Dominov, J. A., Kegley, K. M., and Miller, J. B. (2003) Regeneration of skeletal muscles with altered timing of expression of the myogenic bHLH factor MRF4. <em>Am. J. Pathol.<\/em> 162:1685-1691.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Kostek, C., Dominov, J.A., and Miller, J.B. (2002) Upregulation of MHC class I accompanies, but is not required for, spontaneous myopathy in dysferlin-deficient SJL\/J mice. <em>Am. J. Pathol.<\/em> 160:833-839.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miller, J. B. (2001) Developmental biology of skeletal muscle. In: <em>Disorders of Voluntary Muscle<\/em>, 7th edition (Camb. U. Press) Eds. G. Karpati, R.C. Griggs &amp; D. Hilton-Jones pp 26-41.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Dominov, J.A., Houlihan-Kawamoto C. A., Swap C. J., and Miller, J.B. (2001). Pro- and anti-apototic members of the Bcl-2 family in skeletal muscle: A distinct role for Bcl-2 in later stages of myogenesis. <em>Dev. Dynam.<\/em> 220:18-26.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Schaefer, L., Engman, H., and Miller, J. B. (2000). Coding sequence, chromosomal localization, and expression pattern of Nrf1: the mouse homolog of Drosophila erect-wing. <em>Mammalian Genome<\/em> 11:104-110.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Schaefer, L., Beermann, M. L., and Miller, J. B. (1999). Coding sequence, genomic organization, chromosomal localization, and expression pattern of the signalosome component Cops2: The mouse homologue of Drosophila alien. <em>Genomics<\/em> 56:310-316.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miller, J. B., Schaefer, L., and Dominov, J. A. (1999) Seeking muscle stem cells. <em>Curr. Top. Dev. Biol.<\/em> 43, 191-219.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Dominov, J.A., Dunn, J.J., and Miller, J.B. (1998) Bcl-2 expression identifies an early stage of myogenesis and promotes clonal expansion of muscle cells. <em>J. Cell Biol.<\/em> 142:537-544.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Zhu, Z. and Miller, J.B. (1997) MRF4 can substitute for myogenin during early stages of myogenesis. <em>Dev. Dynam.<\/em> 209:233-241.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Mei, L., Kachinsky, A. M., Seiden, J. E., Kuncl, R.W., Miller, J. B. and Huganir, R. L. (1996) Differential expression of PTP1D, a protein tyrosine phosphatase with two SH2 domains, in a slow and fast skeletal muscle fibers. <em>Exp. Cell Res.<\/em> 224:379-390.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Nikovits, W., Wang, G., Feldman, J. L., Miller, J. B., Wade, R., Nelson, L., and Stockdale, F. E. (1996) Isolation and characterization of an avian slow myosin heavy chain gene expressed during embryonic skeletal muscle fiber formation. <em>J. Biol. Chem.<\/em> 271:17047-53.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Dominov, J.A. and Miller, J.B. (1996) POU homeodomain genes and myogenesis. <em>Dev. Genet.<\/em> 19:108-118.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Block, N.E., Zhu, Z., Kachinsky, A.M., Dominov, J.A., and Miller, J.B. (1996) Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice. <em>Dev. Dynam.<\/em> 207:382-394.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miller, J.B. (1995) Making one cell from two. <em>Nature<\/em> 377:575-576.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miller, J.B. and Boyce, F.M. (1995) Gene therapy by and for muscles. <em>Trends Genet.<\/em> 11:163-165.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Smith, T.H. and Miller, J.B. (1994) Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins. <em>J. Cell Biol.<\/em> 127, 95-105.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 120%; font-size: large;\">Smith, T.H., Block, N.E., Rhodes, S.J., Konieczny, S.F. and Miller, J.B. (1993) A unique pattern of expression of the four muscle regulatory factors distinguishes somitic from embryonic, fetal, and newborn mouse myogenic cells. <em>Development <\/em>117:1125-1133.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Miner, J.H., Miller, J.B., and Wold, B.J. (1992) Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic mouse hearts. <em>Development<\/em> 114:853-860.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 120%; font-size: large;\">Miller, J.B. (1992) Myoblast diversity in skeletal myogenesis: How much and to what end? <em>Cell<\/em> 69:1-3.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"line-height: 110%; font-size: large;\">Block, N.E. and Miller, J.B. (1992) MRF4, a myogenic helix-loop-helix protein, produces multiple changes in the myogenic program of BC3H-1 cells. <em>Mol. Cell. Biol.<\/em> 12:2484-2492.<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Selected Publications Beermann, M.L., Homma, S., and Miller, J.B. (2022) Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: A pilot study. BMC Research Notes 15:163. online access Masteika, I. F., Sathya, A., Homma, S., Miller, B.M., Boyce, F.M., and Miller, J.B. (2022) Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic [&hellip;]<\/p>\n","protected":false},"author":6862,"featured_media":0,"parent":0,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/pages\/22"}],"collection":[{"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/users\/6862"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/comments?post=22"}],"version-history":[{"count":50,"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/pages\/22\/revisions"}],"predecessor-version":[{"id":1165,"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/pages\/22\/revisions\/1165"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/jeffreyboonemiller\/wp-json\/wp\/v2\/media?parent=22"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}