{"id":21,"date":"2019-11-09T11:48:03","date_gmt":"2019-11-09T16:48:03","guid":{"rendered":"https:\/\/sites.bu.edu\/demrlab\/?page_id=21"},"modified":"2021-10-05T14:48:47","modified_gmt":"2021-10-05T18:48:47","slug":"projects","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/demrlab\/projects\/","title":{"rendered":""},"content":{"rendered":"<p><img loading=\"lazy\" src=\"\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-573x636.jpeg\" alt=\"\" width=\"350\" height=\"388\" class=\"aligncenter wp-image-198\" style=\"border: 3px solid #000080;\" srcset=\"https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-573x636.jpeg 573w, https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-923x1024.jpeg 923w, https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-768x852.jpeg 768w, https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-1384x1536.jpeg 1384w, https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334-1845x2048.jpeg 1845w, https:\/\/sites.bu.edu\/demrlab\/files\/2021\/10\/IMG_3619-scaled-e1633459458334.jpeg 1920w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/p>\n<p>The Development, Experience, &amp; Motor Recovery Lab uses a variety of techniques including brain imaging, non-invasive brain stimulation, and behavioral assessments to understand motor development and brain function. In particular, we are interested in studying how sensorimotor experiences shape the development of motor circuits involved in the control of the hands and arms. Our goal is to use this information to develop targeted therapies.<\/p>\n<p><img loading=\"lazy\" src=\"\/demrlab\/files\/2020\/09\/CST-development-01-636x258.png\" alt=\"Atypical brain development model\" width=\"636\" height=\"258\" class=\"aligncenter wp-image-70 size-medium\" srcset=\"https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/CST-development-01-636x258.png 636w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/CST-development-01-1024x415.png 1024w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/CST-development-01-768x311.png 768w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/CST-development-01-1536x622.png 1536w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/CST-development-01-2048x829.png 2048w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/p>\n<p><strong>Functional Near-infrared Spectroscopy (fNIRS)<\/strong><\/p>\n<p data-wp-editing=\"1\"><img loading=\"lazy\" src=\"\/demrlab\/files\/2020\/09\/fnirs-01-636x358.png\" alt=\"functional imaging model\" width=\"523\" height=\"294\" class=\"alignleft wp-image-77\" style=\"border: 3px solid #000080;\" vertical-align:middle=\"\" margin:=\"\" 3px=\"\" srcset=\"https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/fnirs-01-636x358.png 636w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/fnirs-01-1024x576.png 1024w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/fnirs-01-768x432.png 768w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/fnirs-01-1536x864.png 1536w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/fnirs-01-2048x1152.png 2048w\" sizes=\"(max-width: 523px) 100vw, 523px\" \/>fNIRs is a non-invasive method for studying functional brain activity. Given the relatively easy set-up of this imaging tool (a cap worn on the head), fNIRS is particularly suited for measuring brain function in infants and children. We use fNIRS to study 1) how spontaneous infant movements shape brain activity, and 2) how movement therapy improves brain function in older children. We work closely with the community of interdisciplinary collaborators at the <a href=\"https:\/\/www.bu.edu\/neurophotonics\/\" target=\"_blank\" rel=\"noopener noreferrer\">BU Neurophotonics Center<\/a> to deploy state-of-the-art brain imaging technologies to understand how the brain works in health and following neurological damage.<\/p>\n<p data-wp-editing=\"1\">\n<p data-wp-editing=\"1\">\n<p data-wp-editing=\"1\"><strong>Transcranial Magnetic Stimulation (TMS)<\/strong><\/p>\n<p><img loading=\"lazy\" src=\"\/demrlab\/files\/2020\/09\/Burke-194-636x425.jpg\" alt=\"transcranial magnetic stimulation performed with a child\" width=\"636\" height=\"425\" class=\"alignright wp-image-87 size-medium\" style=\"border: 3px solid #000080;\" vertical-align:middle=\"\" margin:=\"\" 3px=\"\" srcset=\"https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/Burke-194-636x425.jpg 636w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/Burke-194-1024x684.jpg 1024w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/Burke-194-768x513.jpg 768w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/Burke-194-1536x1025.jpg 1536w, https:\/\/sites.bu.edu\/demrlab\/files\/2020\/09\/Burke-194-2048x1367.jpg 2048w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/p>\n<p data-wp-editing=\"1\">TMS is a form of non-invasive brain stimulation that can be used to map brain areas responsible for the control of the hands. We use TMS to probe the integrity and excitability of motor systems following intensive rehabilitation. In our lab, TMS is done at rest: children can relax and watch a movie while we perform the measurements. We encourage you to view a <a href=\"https:\/\/www.youtube.com\/watch?v=o2RHeuljPTA&amp;list=PLLTzeUov0U-fiOthEs_19rYRjFgwWdG-q&amp;index=6\" target=\"_blank\" rel=\"noopener noreferrer\">video<\/a> our collaborator, <a href=\"https:\/\/burke.weill.cornell.edu\/friel-lab\" target=\"_blank\" rel=\"noopener noreferrer\">Kathleen Friel<\/a>, PhD, made with children describing what it feels like to be part of a TMS study.<\/p>\n<p data-wp-editing=\"1\"><strong>Diffusion Tensor Imaging (DTI)<\/strong><\/p>\n<p data-wp-editing=\"1\">DTI is a brain imaging technique that enables the measurement of white matter pathways. We use DTI to understand how brain lesions that occur early in development affect the organization of motor and sensory pathways. By understanding how these pathways reorganize, we hope to discover mechanisms of plasticity that can support adaptive motor function following developmental brain injury.<\/p>\n<p data-wp-editing=\"1\"><img loading=\"lazy\" src=\"\/demrlab\/files\/2020\/09\/dwi2.png\" alt=\"diffusion tensor imaging model\" width=\"567\" height=\"480\" class=\"aligncenter wp-image-85 size-full\" style=\"border: 3px solid #000080;\" vertical-align:middle=\"\" margin:=\"\" 3px=\"\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Development, Experience, &amp; Motor Recovery Lab uses a variety of techniques including brain imaging, non-invasive brain stimulation, and behavioral assessments to understand motor development and brain function. In particular, we are interested in studying how sensorimotor experiences shape the development of motor circuits involved in the control of the hands and arms. Our goal [&hellip;]<\/p>\n","protected":false},"author":17011,"featured_media":0,"parent":0,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/pages\/21"}],"collection":[{"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/users\/17011"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/comments?post=21"}],"version-history":[{"count":20,"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/pages\/21\/revisions"}],"predecessor-version":[{"id":199,"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/pages\/21\/revisions\/199"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/demrlab\/wp-json\/wp\/v2\/media?parent=21"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}