{"id":25,"date":"2019-03-16T10:00:58","date_gmt":"2019-03-16T14:00:58","guid":{"rendered":"https:\/\/sites.bu.edu\/ctmlab\/?page_id=25"},"modified":"2019-10-31T15:23:44","modified_gmt":"2019-10-31T19:23:44","slug":"projects","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/ctmlab\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"<p>Our lab&#8217;s technical expertise lies at the intersection of biology, mechanics, and physics.\u00a0 Our experimental projects span a wide range of size scales including nanoparticle design for targeted drug delivery, tensile testing of extracellular matrix fibers, quantifying biological response to stretch in cells and tissue strips, and measuring total pulmonary mechanical function in ventilated patients.\u00a0 We love mathematical equations, and we strive to develop analytical and numerical models that reveal new insights or predictions about complex biomechanical behaviors.\u00a0 Please read more about our active research projects:<\/p>\n<ul><\/ul>\n<div class=\"bu-slideshow-container projects autoplay\" id=\"bu-slideshow-container-105\" data-slideshow-name=\"projects\" data-slideshow-delay=\"3000\" style=\"width: auto; \"><div class='slideshow-loader active'><div class='loader-animation'><\/div><p>loading slideshow...<\/p><\/div><div class=\"bu-slideshow-slides\"><ul class=\"bu-slideshow transition-slide\" id=\"bu-slideshow-105\"><li id=\"bu-slideshow-105_0\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-left\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/multi-scale-modeling-of-fibrosis-emphysema\/\"><img src=\"\/ctmlab\/files\/2019\/09\/spring_breakage_2d_color_crop.gif\" alt=\"\" \/><\/a><div class=\"bu-slide-caption caption-bottom-left\"><p class=\"bu-slide-caption-title\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/multi-scale-modeling-of-fibrosis-emphysema\/\">Multi-Scale Modeling of Fibrosis &amp; Emphysema<\/a><\/p><p class=\"bu-slide-caption-text\">Constructing an open-source framework for investigating disease initiation, progression, and treatment strategies, based on the emergent behaviors of complex interactions between cells and their environments.<\/p><\/div><\/div><\/li><li id=\"bu-slideshow-105_1\" class=\"slide \"><div class=\"bu-slide-container slide-caption-top-left\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/bronchial-particle-deposition\/\"><img src=\"\/ctmlab\/files\/2019\/07\/nasal_particles_front.gif\" alt=\"\" \/><\/a><div class=\"bu-slide-caption caption-top-left\"><p class=\"bu-slide-caption-title\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/bronchial-particle-deposition\/\">Bronchial Particle Deposition<\/a><\/p><p class=\"bu-slide-caption-text\">Identifying key determinants of targeted drug deposition during low-flow conditions.<\/p><\/div><\/div><\/li><li id=\"bu-slideshow-105_2\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-left\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/biomechanical-determinants-of-emphysema-progression\/\"><img src=\"\/ctmlab\/files\/2019\/09\/supercluster_rotating.gif\" alt=\"\" \/><\/a><div class=\"bu-slide-caption caption-bottom-left\"><p class=\"bu-slide-caption-title\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/biomechanical-determinants-of-emphysema-progression\/\">Biomechanical Determinants of Emphysema Progression<\/a><\/p><p class=\"bu-slide-caption-text\">Using computational models to predict force-based tissue destruction, and assess the efficacy of interventional lung volume reduction.<\/p><\/div><\/div><\/li><li id=\"bu-slideshow-105_3\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-left\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/analytical-modeling-of-alveolar-and-lung-tissue-behavior\/\"><img src=\"\/ctmlab\/files\/2019\/10\/Analytical-Models-636x360.png\" alt=\"\" \/><\/a><div class=\"bu-slide-caption caption-bottom-left\"><p class=\"bu-slide-caption-title\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/analytical-modeling-of-alveolar-and-lung-tissue-behavior\/\">Analytical Modeling of Alveolar and Lung Tissue Mechanics<\/a><\/p><p class=\"bu-slide-caption-text\">Uniaxial lung tissue model (left) and alveolar model (right)<\/p><\/div><\/div><\/li><li id=\"bu-slideshow-105_4\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-left\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/assessing-respiratory-mechanics-in-ventilated-patients\/\"><img src=\"\/ctmlab\/files\/2019\/10\/Figure-1-Patients-ZVV-Demonstration.jpg\" alt=\"\" \/><\/a><div class=\"bu-slide-caption caption-bottom-left\"><p class=\"bu-slide-caption-title\"><a href=\"http:\/\/sites.bu.edu\/ctmlab\/projects\/assessing-respiratory-mechanics-in-ventilated-patients\/\">Assessing Respiratory Mechanics in Ventilated Patients<\/a><\/p><p class=\"bu-slide-caption-text\">Novel strategy to assess respiratory mechanics<\/p><\/div><\/div><\/li><\/ul><\/div><div class=\"bu-slideshow-navigation-container\"><ul class=\"bu-slideshow-navigation nav-number\" id=\"bu-slideshow-nav-105\" aria-hidden=\"true\"><li><a href=\"#\" id=\"pager-1\" class=\" active\" aria-hidden=\"true\"><span>1<\/span><\/a><\/li> <li><a href=\"#\" id=\"pager-2\" class=\"\" aria-hidden=\"true\"><span>2<\/span><\/a><\/li> <li><a href=\"#\" id=\"pager-3\" class=\"\" aria-hidden=\"true\"><span>3<\/span><\/a><\/li> <li><a href=\"#\" id=\"pager-4\" class=\"\" aria-hidden=\"true\"><span>4<\/span><\/a><\/li> <li><a href=\"#\" id=\"pager-5\" class=\"\" aria-hidden=\"true\"><span>5<\/span><\/a><\/li> <\/ul><\/div><\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our lab&#8217;s technical expertise lies at the intersection of biology, mechanics, and physics.\u00a0 Our experimental projects span a wide range of size scales including nanoparticle design for targeted drug delivery, tensile testing of extracellular matrix fibers, quantifying biological response to stretch in cells and tissue strips, and measuring total pulmonary mechanical function in ventilated patients.\u00a0 [&hellip;]<\/p>\n","protected":false},"author":16077,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/pages\/25"}],"collection":[{"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/users\/16077"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":13,"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":230,"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/pages\/25\/revisions\/230"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/ctmlab\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}