{"id":325,"date":"2022-03-15T12:18:11","date_gmt":"2022-03-15T16:18:11","guid":{"rendered":"https:\/\/sites.bu.edu\/chagas\/?page_id=325"},"modified":"2026-07-08T13:17:14","modified_gmt":"2026-07-08T17:17:14","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/chagas\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Papers<\/strong><\/p>\n

Carrion MN, Kienle RM, Bourque D, Drainoni ML, Hochberg NS, Dauphinais M, Mello T, Stigler Granados PE, Hamer DH. Barriers to Chagas disease screening among primary care providers in the United States. Am J Trop Med Hyg. 2026;114(5):857-864. doi:10.4269\/ajtmh.25-0559<\/p>\n

Reifler K, Wheelock A, Hall SM, Dauphinais M, Roytburd S, Maiullari M, Salazar A, Maldonado A, West HM, Kohler JR, Barnett ED, Gopal DM, Hamer DH, Bourque DL. Antitrypanosomal therapy for Chagas disease: a single center experience with adverse drug reactions and strategies for enhancing treatment completion. PLoS Negl Trop Dis. 2025;19(7):e0013218. doi:10.1371\/journal.pntd.0013218<\/p>\n

Huerta JV, Maldonado A, Milliren C, Hertig J, Collins K, Gomes J, Salazar A, Bourque DL, Hochberg NS, Hamer DH, Levin LL, Gallegos Salazar J, Barnett ED, Huanuco J, Manne-Goehler J, Kohler JR. Strong Hearts Program: results of a novel primary-care based Chagas disease care program in East Boston, MA, 2017-2023. Open Forum Infect Dis. 2025;12(suppl 1):ofae631.1090.<\/p>\n

Reifler K, Campbell JI, Barnett ED, Bourque DL, Hamer DH, Samra H, Camelo I. Diagnosing Chagas in pregnancy and childhood: what\u2019s old and new. Clin Lab Med. 2025;45(1):73-86. doi:10.1016\/j.cll.2024.10.004<\/p>\n

Agudelo Higuita NI, Beatty NL, Forsyth C, Henao-Martinez AF, Manne-Goehler J; US Chagas Research Consortium. Chagas disease in the United States: a call for increased investment and collaborative research. Lancet Reg Health Am. 2024;34:100768. doi:10.1016\/j.lana.2024.100768<\/p>\n

Wheelock A, Sandhu S, Reifler K, et al. Improving Clinician Awareness of and Screening for Chagas Disease with an Educational Intervention.\u00a0<\/span>Am J Trop Med Hyg<\/i>. 2024;111(2):380-386. Published 2024 Jun 18. doi:10.4269\/ajtmh.23-0483<\/span><\/p>\n

Reifler KA, Wheelock A, Hall SM, Salazar A, Hassan S, Bostrom JA, Barnett ED, Carrion M, Hochberg NS, Hamer DH, Gopal DM, Bourque D. Chagas cardiomyopathy in Boston, Massachusetts: identifying disease and improving management after community and hospital-based screening. PLoS Negl Trop Dis. 2024;18(1):e0011913. doi:10.1371\/journal.pntd.0011913<\/p>\n

Hochberg NS, Montgomery SP. Chagas disease. Ann Intern Med. 2023;176(2):ITC17-ITC32. doi:10.7326\/AITC202302210<\/p>\n

Hochberg NS, Cooley G, Huynh MM, et al. Assessing a parasitological cure: a perspective on PCR as an endpoint for Chagas disease clinical trials. Front Parasitol. 2023;2:1272386. doi:10.3389\/fpara.2023.1272386<\/p>\n

Crespillo-Andujar C, Comeche B, Hamer DH, Arevalo-Rodriguez I, Alvarez-Diaz N, Zamora J, Perez-Molina JA. Use of benznidazole to treat chronic Chagas disease: an updated systematic review with a meta-analysis. PLoS Negl Trop Dis. 2022;16(5):e0010386. doi:10.1371\/journal.pntd.0010386<\/p>\n

Forsyth CJ, Manne-Goehler J, Bern C, Whitman J, Hochberg NS, Edwards M, Marcus R, Beatty N, Castro Y, Coyle C, Stigler Granados P, Hamer DH, Maguire J, Gilman RH, Meymandi S; US Chagas Diagnostic Working Group. Recommendations for screening and diagnosis of Chagas disease in the United States. J Infect Dis. 2022;225(9):1601-1610. doi:10.1093\/infdis\/jiab513<\/p>\n

Nolan MS, Hochberg NS. Chagas disease in HIV-infected patients: it\u2019s time to consider the diagnosis. Am J Trop Med Hyg. 2021;105(3):545-546. doi:10.4269\/ajtmh.21-0681<\/p>\n

Hochberg NS, Wheelock A, Hamer DH, Marcus R, Nolan MS, Meymandi S, Gilman RH. Chagas disease in the United States: a perspective on diagnostic testing limitations and next steps. Am J Trop Med Hyg. 2021;104(3):800-804. doi:10.4269\/ajtmh.19-0871<\/p>\n

Wheelock AE, Sandhu SK, Loskill AJ, Marcus RR, Gopal DM, Hamer DH, Hochberg NS. Testing for Chagas disease in an at-risk population. J Card Fail. 2021;27(1):109-111. doi:10.1016\/j.cardfail.2020.09.002<\/p>\n

Case Reports<\/strong><\/p>\n

Beatty N, Alcala R, Luque N, Radetic M, Joshi-Guske P, Alakrad E, Forsyth C, Hamer DH. Chagas disease in a traveler who developed esophageal involvement decades after acute infection. Am J Trop Med Hyg. 2023;108(3):543-547.<\/p>\n

\n

Abstracts<\/strong><\/p>\n

Reifler K, Sinha P, Dauphinais M, Hamer DH, Bourque D. Good for hearts, better for budgets: a cost-effectiveness evaluation of screening for Chagas disease. Oral abstract 6089 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; November 2025; Toronto, Canada.<\/p>\n

Huerta JV, Maldonado A, Milliren C, Hertig J, Collins K, Gomes J, Salazar A, Bourque DL, Hochberg NS, Hamer DH, Levin LL, Gallegos Salazar J, Barnett ED, Huanuco J, Manne-Goehler J, Kohler JR. Strong Hearts Program: results of a novel primary-care based Chagas disease care program in East Boston, MA, 2017-2023. Open Forum Infect Dis. 2025;12(suppl 1):ofae631.1090.<\/p>\n

Reifler K, Wheelock A, Carrion M, Kimball S, Barnett E, Hochberg NS, Bourque D, Hamer DH. Impact of educational activities and an electronic medical record template on Chagas disease screening. Poster abstract 7452 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; November 2024; New Orleans, LA.<\/p>\n

Wheelock A, Reifler K, Salazar A, Hall S, Hamer DH, Hochberg NS, Bourque DL. Facing adversity: Chagas disease treatment tolerability and adverse events at an academic safety-net hospital in New England. Oral abstract 6415 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; October 2023; Chicago, IL.<\/p>\n

Crespillo-Andujar C, Smith TC, Bart SM, Grobusch MP, Connor BA, Angheben A, Libman M, Arsuaga M, Diaz-Menendez M, Molina I, Gautret P, Perez-Molina JA, Gobbi FG, Huits R, Hochberg NS, Hamer DH. Chronic Chagas disease: a descriptive analysis from the GeoSentinel Network, 2014-2021. Oral abstract 133 presented at: Conference of the International Society of Travel Medicine; May 2023; Basel, Switzerland.<\/p>\n

Reifler K, Hall S, Wheelock A, Gopal D, Hochberg NS, Hamer DH, Bourque DL. Without skipping a beat: symptoms and sequelae of Chagas disease among migrants in a non-endemic region. Moderated poster abstract 120 presented at: Conference of the International Society of Travel Medicine; May 2023; Basel, Switzerland.<\/p>\n

Dauphinais M, Wheelock A, Levin A, Irani V, Buonomo G, Azocar A, Vasquez M, Ragan EJ, Duffy E, Paiva T, Carrion M, Salazar A, Bourque D, Hamer DH, Hochberg NS. A longitudinal cohort and biorepository in Boston, Massachusetts to address key questions in Chagas disease. Abstract 1654 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; November 1, 2022; Seattle, WA.<\/p>\n

Carrion MN, Wheelock A, Dauphinais M, Bourque DL, Hamer DH, Hochberg NS. Case studies and workflow integration: how to encourage primary care providers to screen for Chagas disease. Abstract 1053 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; November 1, 2022; Seattle, WA.<\/p>\n

Wheelock A, Sukhmeet S, Reifler K, Yarrington C, Kimball S, Cruz R, Paiva T, Dauphinais M, Salazar A, Carrion M, Bourque D, Gopal D, Camelo I, Hamer DH, Hochberg NS. Slow but steady: working to increase Chagas disease testing through an educational intervention at a safety-net hospital. Abstract 447 presented at: American Society of Tropical Medicine and Hygiene Annual Meeting; October 31, 2022; Seattle, WA.<\/p>\n

Reifler K, Campbell JI, Barnett ED, et al. Diagnosing Chagas in Pregnancy and Childhood: What’s Old and New.\u00a0<\/span>Clin Lab Med<\/i>. 2025;45(1):73-86. doi:10.1016\/j.cll.2024.10.004<\/span>. <\/span>\u00a0Chagas Diagnosis in Pregnancy and Childhood Clin Lab abstract <\/a>.<\/span><\/span>\u00a0<\/span><\/p>\n

Wheelock A, Sandhu S,\u00a0<\/span><\/span><\/span>Reifler K,\u00a0<\/span><\/span><\/span>Carrion M, Bourque DL, Hamer DH, Hochberg NS. Improving clinician awareness and screening for Chagas disease with an educational Intervention<\/em>.<\/span>\u00a0<\/span><\/span>Chagas Awareness and Screening AJTMH abstract<\/a>.<\/span><\/p>\n

Wheelock, A., Sandhu, S., Bielick, C., Reifler, K., Carrion, M., Janiszewski, K., Hamer, D., & Hochberg, N. (n.d.). 2021 ASTMH Annual Meeting . In Is education enough? An intervention to improve screening for Chagas disease at an academic safety net hospital in the US<\/i>. Chagas Ed ASTMH abstract<\/a><\/p>\n

Kimball, A., Bourque, D., Hochberg, N. 2021 SGIM Annual Conference. In Caring for the Cross-Border Migrant: Addressing Equity in Care. SGIM 2022<\/a><\/em><\/p>\n

\n

Presentations<\/strong><\/p>\n

Reifler K, Sinha P, Dauphinais M, Bourque DL. \u201cGood for Hearts, Better for Budgets: a cost-effectiveness evaluation of screening for Chagas disease. Oral presentation at American Society of Tropical Medicine and Hygiene (ASTMH), Toronto,\u00a0CA. 2025.<\/p>\n

Reifler K, Dauphinais M, Wheelock A, Carrion M, Kimball S, Barnett E, Hochberg N, Bourque DL, Hamer DH. \u201cImpact of Educational Activities and an Electronic Medical Record Template on Chagas Disease Screening.\u201d Poster presentation at American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, LA.\u00a0 2024.<\/p>\n

Reifler K,\u00a0Wheelock AW, Dauphinais M, Hamer DH, Bourque DL. \u201cNavigating Barriers: Chagas disease treatment tolerability and adverse events in Boston.\u201d Oral presentation at the Novartis New England Neglected Tropical Diseases Consortium, Cambridge, MA. 2024.<\/p>\n

Reifler K,\u00a0Wheelock A, Hochberg N, Hamer DH, Gopal D, Bourque DL. \u201cChagas Cardiomyopathy in Boston, Massachusetts: Identifying Disease and Improving Management After Community and Hospital-Based Screening.\u201d Oral and poster presentations at\u00a0University\u00a0of Texas Medical Branch 1st\u00a0Annual Symposium on Tropical and Emerging Infectious Diseases for Clinicians and Translational Scientists, Galveston, TX. 2024.<\/p>\n

Wheelock A,\u00a0Reifler K, Salazar A, Hall S, Hamer DH, Hochberg N, Bourque DL. \u201cFacing Adversity: Chagas Disease Treatment Tolerability and Adverse Events at an Academic Safety-Net Hospital in New England.\u201d Oral presentation at the American Society of Tropical Medicine and Hygiene meeting, Chicago, IL. 2023.<\/p>\n

Wheelock A,\u00a0Reifler K, Hochberg N, Hamer D, Gopal D, Bourque DL. \u201cMigration Timing and its Association with Chagas Disease Features in a Chagas Disease Cohort in New England.\u201d Poster presented at ID Week, Boston, MA. 2023.<\/p>\n

Hamer D,\u00a0Reifler K. \u201cChagas Disease at Boston Medical Center: Not as Exotic as It Sounds.\u201d Department of Family\u00a0Medicine\u00a0Grand Rounds, Boston University School of Medicine, Boston, MA. 2023.<\/p>\n

Reifler K,\u00a0Hall S, Wheelock A, Gopal D, Hochberg N, Hamer DH, Bourque DL. \u201cWithout Skipping a Beat: Symptoms and Sequelae of Chagas Disease Among Migrants in a Non-Endemic Region.\u201d Oral presentation at the Conference of International Society of Travel Medicine, Basel, Switzerland. 2023.<\/p>\n

Reifler K,\u00a0Hall S, Wheelock A, Hamer D, Gopal D, Hochberg N. \u201cThe Heart of the Matter: Cardiac Involvement of Chagas Disease at a Tropical Medicine Clinic in Boston.\u201d Oral presentation at the American Society of Tropical Medicine and Hygiene meeting (virtual due to COVID-19). 2021.<\/p>\n

Wheelock A, Sandhu S,\u00a0Reifler K,\u00a0Bielick\u00a0C,\u00a0Niemierko\u00a0M, Hamer DH, Hochberg, N. \u201cIs Education Enough? An Intervention to Improve Screening for Chagas Disease at an Academic Safety Net Hospital in the US.\u201d Poster presented at the American Society of Tropical Medicine and Hygiene meeting (virtual due to COVID-19). 2021.<\/p>\n

Reifler K, Hall S, Hamer DH, Gomes J, Yarrington C, Barnett E, Carrion M, Manne-Goehler J, Koehler J, Gopal D, Salazar A, Hochberg N. \u201cTreatment of Chagas Disease at an Urban Academic Medical Center in Boston.\u201d Poster presented at the Conference of the International Society of Travel Medicine (virtual due to COVID-19). 2021.<\/p>\n

Wheelock A,\u00a0Reifler K. \u201cChagas Disease at Boston Medical Center: Optimizing Screening and Referral Practices in General Internal Medicine.\u201d Department of Internal\u00a0Medicine\u00a0Grand Rounds, Boston University School of Medicine, Boston, MA. 2021.<\/p>\n

Alyse Wheelock, MD<\/span>, Sukhmeet Sandhu, MD<\/span>, Alyssa Loskill, BA<\/span>, Rachel Marcus, MD<\/span>, Deepa Gopal, MD<\/span>, Davidson. H. Hamer, MD<\/span>\u00a0<\/sup>\u00a0<\/span>Natasha Hochberg, MD, MPH. Testing for Chagas Cardiac\u00a0Disease at a Large Safety-net Hospital in New England. Boston University Internal Medicine Residency Program. 2020. [Link]<\/a><\/span><\/p>\n

 <\/p>\n

\n

Invited Talks and Lectures<\/strong><\/p>\n

Hamer DH. Maternal-child health approaches for early detection and prevention in Chagas disease. Session chair at: First Annual US Chagas Disease Meeting; March 27, 2026; New Orleans, LA.<\/p>\n

Hamer DH. Chagas disease in non-endemic countries: strategies for screening and treating. Environmental Medicine Grand Rounds, Mt. Sinai Hospital; March 19, 2026; New York, NY.<\/p>\n

Hamer DH, Bourque DL, Gopal D. An unseen threat to the heart: Chagas disease in Boston. Department of Medicine Grand Rounds, Boston University Chobanian & Avedisian School of Medicine; March 6, 2026; Boston, MA.<\/p>\n

Hamer DH. Chagas transmission, screening, and prevention. Presented in The Kiss of Death: An Update on Chagas Disease symposium at: Conference of the International Society of Travel Medicine; May 14, 2025; New Orleans, LA.<\/p>\n

Hamer DH. How to screen for and diagnose Chagas disease. Invited presentation for Chagas Echo series: Session 2 – Recommendations on how to screen, diagnose, and treat Chagas disease at federally qualified health centers and other safety-net healthcare practices; Chagas Disease Clinical Network; February 14, 2025.<\/p>\n

Hamer DH. Chagas disease in the US: an approach to screening and treatment of this neglected tropical disease. Infectious Diseases Grand Rounds, Baystate Medical Center; December 4, 2024; virtual.<\/p>\n

Hamer DH, Herrera C. New perspectives on human autochthonous Chagas disease in the United States and Mexico. Symposium co-chair at: American Society of Tropical Medicine and Hygiene Annual Meeting; November 16, 2024; New Orleans, LA.<\/p>\n

Hamer DH, Bourque DL. Enfermedad de Chagas en EE.UU.: \u00bfPor qu\u00e9 debemos examinarla y a qui\u00e9n afecta esta enfermedad tropical negligenciada? Facebook webinar for the Mexican Consulate; October 28, 2024; Boston, MA.<\/p>\n

Reifler K. Chagas disease at Boston Medical Center. Lecture to internal medicine residents, Boston University Chobanian & Avedisian School of Medicine; October 2024; Boston, MA.<\/p>\n

Hamer DH. Boston Medical Center and Boston University Chagas disease screening and research activities. Presented at: Clinical Directors Network Chagas meeting; September 16, 2024.<\/p>\n

Hamer DH, Coyle C. World Chagas Day Symposium. Symposium co-chair and clinical case discussion chair with David Martin and Daniel Bourque; April 12, 2024.<\/p>\n

Hamer DH. Boston Medical Center and Boston University research on Chagas disease. Presented to: Chagas Disease Clinical and Translational Research Working Group; April 8, 2024.<\/p>\n

Hamer DH. Chagas disease in US migrants – from screening to treatment. Primary Care Grand Rounds, East Boston Neighborhood Health Center; November 14, 2023; Boston, MA.<\/p>\n

Hamer DH. Chagas disease: best practices for clinical care. Co-chair and organizer at: American Society of Tropical Medicine and Hygiene Annual Meeting; October 20, 2023; Chicago, IL.<\/p>\n

Hamer DH, Reifler K. Chagas disease at Boston Medical Center: not as exotic as it sounds. Family Medicine Grand Rounds, Boston Medical Center; October 3, 2023; Boston, MA.<\/p>\n

Hamer DH. Chagas disease: screening and treatment. Presented virtually to: Yale Chagas Health Interest Group; October 2, 2023.<\/p>\n

Hamer DH. Screening for Chagas disease. Presented virtually to: Section of Infectious Diseases, Baystate Medical Center; September 28, 2023; Springfield, MA.<\/p>\n

Reifler K. A case of preventable heart disease. LEADS Medical Student Lecture, Boston University Chobanian & Avedisian School of Medicine; September 2023; Boston, MA.<\/p>\n

Reifler K. Chagas disease at Boston Medical Center: less exotic than it sounds. Lecture to internal medicine residents, Boston University Chobanian & Avedisian School of Medicine; August 2023; Boston, MA.<\/p>\n

Hamer DH, Bourque DL, Salazar A. Treatment of Chagas disease: successes and pitfalls. Panel presentation at: Bedside Tropical Medicine Rounds, Albert Einstein College of Medicine; April 18, 2023.<\/p>\n

Reifler K. A case from the tropics. Chagas disease case lecture to internal medicine residents, Boston University Medical Center; February 2022; Boston, MA.<\/p>\n

Wheelock A, Reifler K. Chagas disease at Boston Medical Center: optimizing screening and referral practices in general internal medicine. Department of Internal Medicine Grand Rounds, Boston University School of Medicine; May 2021; Boston, MA.<\/p>\n

\n

Media<\/strong><\/p>\n

Bailey August 26, M. (2021, August 26). Bettering Chagas Disease Screening is an immigrant health equity issue<\/i>. HealthCity. Retrieved March 15, 2022, from https:\/\/healthcity.bmc.org\/policy-and-industry\/bettering-chagas-disease-screening-immigrant-health-equity-issue\u00a0<\/a><\/p>\n

Doc Molly podcast: D<\/span>ialogue for clinicians to use with their Spanish-speaking patients to walk them through the process of Chagas screening, diagnosis, and follow-up care.\u00a0<\/span>https:\/\/docmolly.com\/detection-chagas-disease\/<\/span><\/a>\u00a0.<\/span>\u00a0<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Papers Carrion MN, Kienle RM, Bourque D, Drainoni ML, Hochberg NS, Dauphinais M, Mello T, Stigler Granados PE, Hamer DH. Barriers to Chagas disease screening among primary care providers in the United States. Am J Trop Med Hyg. 2026;114(5):857-864. doi:10.4269\/ajtmh.25-0559 Reifler K, Wheelock A, Hall SM, Dauphinais M, Roytburd S, Maiullari M, Salazar A, Maldonado […]<\/p>\n","protected":false},"author":19589,"featured_media":0,"parent":0,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/pages\/325"}],"collection":[{"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/users\/19589"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/comments?post=325"}],"version-history":[{"count":9,"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/pages\/325\/revisions"}],"predecessor-version":[{"id":464,"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/pages\/325\/revisions\/464"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/chagas\/wp-json\/wp\/v2\/media?parent=325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}