{"id":524,"date":"2023-04-06T16:09:34","date_gmt":"2023-04-06T20:09:34","guid":{"rendered":"https:\/\/sites.bu.edu\/bostoncrc\/?page_id=524"},"modified":"2023-04-26T17:50:56","modified_gmt":"2023-04-26T21:50:56","slug":"mageeupitt","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/bostoncrc\/teams\/mageeupitt\/","title":{"rendered":"Magee-Womens Research Institute &#038; Foundation and University of Pittsburgh"},"content":{"rendered":"<p><a href=\"https:\/\/mageewomens.org\/\"><img loading=\"lazy\" src=\"\/bostoncrc\/files\/2023\/04\/Magee-Composite.png\" alt=\"\" class=\"alignnone size-full wp-image-814\" width=\"896\" height=\"611\" srcset=\"https:\/\/sites.bu.edu\/bostoncrc\/files\/2023\/04\/Magee-Composite.png 896w, https:\/\/sites.bu.edu\/bostoncrc\/files\/2023\/04\/Magee-Composite-636x434.png 636w, https:\/\/sites.bu.edu\/bostoncrc\/files\/2023\/04\/Magee-Composite-768x524.png 768w\" sizes=\"(max-width: 896px) 100vw, 896px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<h4 style=\"text-align: justify;\">Team Members:<\/h4>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/mageewomens.org\/investigator\/lisa-cencia-rohan-ph-d\">Lisa Rohan, Ph.D.<\/a> <strong><\/strong>serves as Co-Lead on Project 3 and will optimize fast- and extended-release film formulations for use with HCA. She is a Professor of Pharmaceutical Sciences and Obstetrics and Gynecology at the University of Pittsburgh and an Investigator at Magee-Women\u2019s Research Institute, Pittsburgh PA. She has a long track record on the development of vaginal dosing forms, and was part of the team that introduced the first antiretroviral vaginal films (dapivirine, tenofovir).<\/p>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/www.pharmacy.pitt.edu\/directory\/profile.php?profile=1860&amp;type=Faculty\">Sravan Kumar Patel, Ph.D.<\/a> serves as co-investigator on the project.<\/p>\n<p style=\"text-align: justify;\"><strong><u>Specific Aims for MWRI\/UP role in Project 3:<\/u><\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>1. <\/strong>Develop improved vaginal film formulations for immediate and extended HCA release.<\/p>\n<p style=\"text-align: justify;\"><strong>2. <\/strong>Optimize the immediate-release vaginal film for use in the proposed clinical trials and transfer the technology to <a href=\"https:\/\/benefitcoatings.com\/\">Benefit Coatings<\/a>, the company that will manufacture the GMP HCA film for ZB-06.<\/p>\n<p style=\"text-align: justify;\"><strong>3. <\/strong>Develop an extended duration-of-use vaginal film that can deliver an effective dose of HCA for <u>&gt;<\/u> 3 days.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Team Members: Lisa Rohan, Ph.D. serves as Co-Lead on Project 3 and will optimize fast- and extended-release film formulations for use with HCA. She is a Professor of Pharmaceutical Sciences and Obstetrics and Gynecology at the University of Pittsburgh and an Investigator at Magee-Women\u2019s Research Institute, Pittsburgh PA. She has a long track record [&hellip;]<\/p>\n","protected":false},"author":19861,"featured_media":0,"parent":285,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/524"}],"collection":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/users\/19861"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/comments?post=524"}],"version-history":[{"count":8,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/524\/revisions"}],"predecessor-version":[{"id":528,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/524\/revisions\/528"}],"up":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/285"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/media?parent=524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}