{"id":34,"date":"2021-11-24T14:41:44","date_gmt":"2021-11-24T18:41:44","guid":{"rendered":"https:\/\/sites.bu.edu\/bostoncrc\/?page_id=34"},"modified":"2026-03-24T16:36:45","modified_gmt":"2026-03-24T20:36:45","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/bostoncrc\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<h3 style=\"text-align: justify;\">Below are listed publications resulting from ongoing Center research activities:<\/h3>\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41176392\/\" target=\"_blank\" rel=\"noopener\"><strong>Biomedical innovations in contraception:\u00a0 gaps, obstacles, and solutions for sexual and reproductive health.<\/strong><\/a><\/h4>\n<p>Anderson DJ, Bearak JM, Grimstad FW, Palanee-Phillips T, van der Straten A. [Invited major article for Lancet series on Sexual and Reproductive Health] The <span>Lancet. 2025 Nov 1;406(10515):2119-2132. doi: 10.1016\/S0140-6736(25)01187-0. PMID:\u00a0<span class=\"docsum-pmid\">41176392<\/span><\/span><\/p>\n<h4 class=\"heading-title\"><a href=\"https:\/\/pdf.sciencedirectassets.com\/271326\/1-s2.0-S0015028225X00029\/1-s2.0-S0015028224023203\/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEHwaCXVzLWVhc3QtMSJHMEUCIEeRrLVn2v1cpzTU4jB8BCzeP6YCshh7DMnHeNLjScKjAiEA%2FitZx0fL8IwMzkOocXCdkbWK5%2FyUmGKDnyff9bYDmKIqvAUIxf%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARAFGgwwNTkwMDM1NDY4NjUiDA2W0nO%2F11tAOljMWiqQBd0APXcPb2cGE839GEAHqWrf4nRBlSuWtoZgxqbHjNuokVu3QgxrC1UcL7K3dY1ke2Kc0TBYUZ1ix%2B8BSqCcPlH1HW1qtc%2Fr1uyavC8Iw9WAk5Avhzh8n7XXjwjuMmIL6pDh5kh88TQ%2BjjZvMEiOXiLRZ8VDHht838wUVpsDfvp1XTVuwaX6oh9oYGsTjdOQHRenVgI8U%2Fkk%2BYe8WezxLgjv1ZTJoj4Lo7fKcDKi7MEzMvQ%2FLFZ41mA4YxbI2NM0spmBrko0vmpSdPEHEsAzs5Z6yJzWnGvIVVnK7g3eU6jR2hW4GQy443st%2FkI6d52o5XWQcikPvhooKrf%2BXikxJvzNwCF26oxF7JhIjh5DvcN4D3R1vdZ3jxIoee13MWFA4aKJO6rJRVYvmtDy1AafvUBFhiEmksbIPpJ1exsLey%2FsytDAofs3tHSv%2F77jXyXdWjp6x%2BouhbsCu%2F1YAuTgkQEKz%2BBZ%2FjwuKrkH9kg0Aks65b4lVGcqkVJshBzjbQxjXGmNoYPsspQ%2FaNnG1HuRrVjGIpbboI1z1X8e2xjUjw6c4iLe8Rn1vcgjA%2F3fy%2B%2FTur8on%2FsRZA1P03qphnNAz5K8Cut4R3xj7iU2a8qsK73x9YKN27jyPCAGeA2xHi2kuVakP5bBG4FMVT59zlYgJWkquaASZZCHf0Q%2Fx6wukUv2a4DobZbzlTJLeuOMrp2jc8cabji50SCJFW30c0EoqUHDIe3HKPKOh5zNmXzv6Qmbsfsj%2BgFe5TQihv3njwefWlFZiJinCgqiiUaRJ0zE%2BT8pCgCD18s5CvLBvukZxdjIziP3suDMGB7Hs1RpImR6WzLywps8mk38euW%2BaFDGWccUdD4mhUi%2F7TovcIuEvbr7MOjCx74GOrEBl1pUO4GjRy0b%2FE32v%2FwGLxefDGWsbzpFBYpZ5qqQwRaO2TRFNnAfwNDRwSGCKLFa94tqjKdp0%2BwCgG5Ru9GUEsSZ1yUpkTw7%2FMjSPvhBwMAasiCfieR9WK4WrT2uuB4QeS%2FlfSW3jTUSlh%2FnQehoiZwNAsyuGlBigsuDS%2FgxeJN35fVGjgC5WTMtOfsBIOF%2FwROBC62gDOhjskWVK3tWivrhSkngw%2FqHT3H%2BIvtmKe%2FR&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20250312T210405Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY6SJGAGZV%2F20250312%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=fe5d138ab8492358b484853da4003ce7a676ff90a150c44d6c1e77756d59780c&amp;hash=5f0295c0c619537e28eb5045795ea446c18daebdd5d6d032dd55d9b8bb4aeeab&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0015028224023203&amp;tid=spdf-98df3497-744a-44ac-85b7-b69fa7b8997e&amp;sid=a61d250d67a1c34361289d7675f4268b15f1gxrqa&amp;type=client&amp;tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&amp;rh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&amp;ua=10155d53095754030654&amp;rr=91f63df3cc978f87&amp;cc=us\">Antibody-dependent complement-mediated sperm cytotoxicity in the endocervix is a dominant contraceptive mechanism of ZB-06 vaginal film.<\/a><\/h4>\n<p>Nador E, Mausser E, Marathe JG, Politch JA, Thurman AR, Whaley KJ, Anderson DJ.\u00a0 Fertil Steril 2025, 123(3):534-536. P<span class=\"identifier pubmed\"><span class=\"id-label\">MID:<span>\u00a0<\/span><\/span><strong class=\"current-id\" title=\"PubMed ID\">39447830\u00a0\u00a0 <\/strong><\/span><span class=\"identifier doi\"><span class=\"id-label\">DOI:<span>\u00a0<\/span><\/span><a class=\"id-link\" target=\"_blank\" rel=\"noopener noreferrer\" ref=\"linksrc=article_id_link&amp;article_id=10.1016\/j.fertnstert.2024.10.026&amp;id_type=DOI\" href=\"https:\/\/doi.org\/10.1016\/j.fertnstert.2024.10.026\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1016\/j.fertnstert.2024.10.026<\/a><\/span><\/p>\n<h4 class=\"title hypothesis_container\" itemprop=\"name\"><a href=\"\/bostoncrc\/files\/2024\/03\/Glycan-Profiles-of-an-Antisperm-Antibody.pdf\">Platform-specific Fc<span>\u00a0<\/span><span class=\"html-italic\">N<\/span>-glycan profiles of an antisperm antibody.<\/a><\/h4>\n<p itemprop=\"name\">Nador E, Xia C, Santangelo, PJ, Whaley KJ, Costello CE, Anderson DJ.\u00a0 <em>Antibodies<\/em><span>\u00a0<\/span>2024<span>,\u00a0<\/span><em>13<\/em><span>(1), 17;\u00a0<\/span><a href=\"https:\/\/doi.org\/10.3390\/antib13010017\">https:\/\/doi.org\/10.3390\/antib13010017<\/a><\/p>\n<h4><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/frph.2023.1337479\/full\"><span><strong>Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy.<\/strong><\/span><\/a><\/h4>\n<p><span>Dohadwala S, Geib, MT, Politch JA, Anderson DJ.\u00a0 <em><span style=\"text-decoration: underline;\">Front Reprod Health.<\/span><\/em>\u00a0 <\/span><span class=\"period\"><\/span><span class=\"cit\">2024 Jan 9:5:1337479. <\/span><span><span class=\"citation-doi\">doi: 10.3389\/frph.2023.1337479. <\/span> <span class=\"secondary-date\"> eCollection 2023. <\/span><em><\/em><\/span><\/p>\n<h4 property=\"name\" style=\"text-align: justify;\"><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adf9341?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\">A brief history and future prospects of contraception<\/a><\/h4>\n<p style=\"text-align: justify;\"><span class=\"docsum-authors full-authors\">Anderson DJ, Johnston DS.<\/span> <span class=\"docsum-journal-citation full-journal-citation\"><span style=\"text-decoration: underline;\"><em>Science.<\/em><\/span> 2023 Apr 14;380(6641):154-158. doi: 10.1126\/science.adf9341. Epub 2023 Apr 13.<\/span><\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/www.dovepress.com\/getfile.php?fileID=90388\"><span>A brief history and advancement of contraceptive multipurpose prevention technology (cMPT).\u00a0\u00a0<\/span><\/a><\/h4>\n<p class=\"x_MsoNormal\"><span>Dohadwala S,\u00a0Politch JA, Barmine JH, Anderson DJ. <span style=\"text-decoration: underline;\"><em>Open Access Journal of Contraception<\/em>.<\/span> 2023; 14: 83-94.<\/span><\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1016\/j.ajog.2023.02.024\">ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study<\/a><\/h4>\n<p style=\"text-align: justify;\">Thurman AR, Moench TR, Hoke M, Politch JA, Cabral H, Mausser E, Nador E, Morton J, Hamorsky K, Swope K, Bratcher B, Anderson DJ, Whaley KJ. <span style=\"text-decoration: underline;\"><em>Am J Obstet Gynecol<\/em>.\u00a0 <\/span><span class=\"period\"><\/span><span class=\"cit\">2023 Jun;228(6):716.e1-716.e12. <\/span><span class=\"citation-doi\">doi: 10.1016\/j.ajog.2023.02.024. <\/span> <span class=\"secondary-date\"> Epub 2023 Mar 2. <\/span><\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0282147\">LALAPG variant of the human contraception antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity<\/a><\/h4>\n<p style=\"text-align: justify;\">Mausser E*, Nador E*, Politch JA, Pauly MR, Marathe JG, Moench TR, Zeitlin L, Whaley KJ, Anderson DJ. <span style=\"text-decoration: underline;\"><em>PLOS ONE<\/em>.<\/span> 2023 Mar 30;18(3):e0282147. doi: 10.1371\/journal.pone.0282147<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1080\/21645515.2021.1965423\"><u>Passive immunization of the human vagina<\/u>.<\/a><\/h4>\n<p style=\"text-align: justify;\">Anderson DJ. <span style=\"text-decoration: underline;\"><em>Hum Vaccin Immunother<\/em>.<\/span> 2022 Apr 7; 18(2): e1965423. doi: 10.21645515. PMID: 3447305, PMCID: PMC9103259.<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abd5219\"><u>Engineering ultra-potent sperm binding IgG antibodies for the development of an effective non-hormonal female contraceptive.<\/u><\/a><\/h4>\n<p style=\"text-align: justify;\">Shrestha B, Schafer A, Saada J, Yong Z, Jacobs T, Chavez E, Omsted S, Cruz-Teran C, Baldeon Vaca G, Vincent K, Moench T, Lai S., <span style=\"text-decoration: underline;\"><em>Science Translational Medicine<\/em>.<\/span> 2021 Aug 11; 13(606):eabd5219,\u00a0 doi: 10.1126\/scitranslmed.abd5219.\u00a0 PMID: 34380769, PMCID: PMC8868023<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1016\/j.ebiom.2021.103478\">Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women.<\/a><\/h4>\n<p style=\"text-align: justify;\">Baldeon Vaca G, Marathe JG, Politch JA, Mausser E, Pudney J, Doud J, Nador E, Zeitlin L, Pauly M, Moench TR, Brennan M, Whaley KJ, Anderson DJ.\u00a0 <span style=\"text-decoration: underline;\"><em>EBioMedicine<\/em>.<\/span> 2021 Jul; 69:103478.\u00a0 doi: 10.1016\/j.ebiom.2021.103478.\u00a0 PMID: 34256345, PMCID: PMC8324805.<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1093\/biolre\/ioaa096\">Engineering monoclonal antibody-based contraception and multipurpose prevention technologies.<\/a><\/h4>\n<p style=\"text-align: justify;\">Anderson DJ,\u00a0Politch JA, Cone RA, Zeitlin L, Lai SK, Santangelo PJ, Moench TR, Whaley KJ.\u00a0 <span style=\"text-decoration: underline;\"><em>Biol Reprod<\/em>.<\/span> 2020 Aug 4;103(2):275-285. doi: 10.1093\/biolre\/ioaa096.\u00a0 PMID:\u00a032607584, PMCID:\u00a0 PMC7401387.<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/doi.org\/10.1007\/s10439-019-02402-1\"><u>Biomaterials and contraception<\/u>: <u>Promises and pitfalls<\/u>.\u00a0<\/a><\/h4>\n<p style=\"text-align: justify;\">Claure I, Anderson D, Kapperich C, Kuohung W, Wong J.\u00a0 <span style=\"text-decoration: underline;\"><em>Ann Biomed Eng<\/em>.<\/span> 2020. July; 48(7): 2113-2131. doi:\u00a0 10.1007\/s10439-019-02402-1.\u00a0 PMID: 31701311, PMCID: PMC7202983.<\/p>\n<h4 style=\"text-align: justify;\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMp1906733\">Population and the Environment &#8211; Time for Another Contraception Revolution<\/a><\/h4>\n<p style=\"text-align: justify;\">Anderson DJ. <span style=\"text-decoration: underline;\"><em>N Engl J Med<\/em>.<\/span> 2019 Aug 1;\u00a0<span class=\"cit\">381(5):397-399. <\/span><span class=\"citation-doi\">doi: 10.1056\/NEJMp1906733. PMID: 31365795, DOI: 10.1056\/NEJMp1906733<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Below are listed publications resulting from ongoing Center research activities: Biomedical innovations in contraception:\u00a0 gaps, obstacles, and solutions for sexual and reproductive health. Anderson DJ, Bearak JM, Grimstad FW, Palanee-Phillips T, van der Straten A. [Invited major article for Lancet series on Sexual and Reproductive Health] The Lancet. 2025 Nov 1;406(10515):2119-2132. doi: 10.1016\/S0140-6736(25)01187-0. PMID:\u00a041176392 Antibody-dependent [&hellip;]<\/p>\n","protected":false},"author":19861,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/34"}],"collection":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/users\/19861"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/comments?post=34"}],"version-history":[{"count":49,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/34\/revisions"}],"predecessor-version":[{"id":983,"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/pages\/34\/revisions\/983"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/bostoncrc\/wp-json\/wp\/v2\/media?parent=34"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}